SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v1a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB152_0 (ILEAL BILE ACID-BINDING PROTEIN)	4v1a	MITORIBOSOMAL PROTEIN ML48, MRPL48 (Sus scrofa)	3 / 3	ASN k 92 HIS k 189 VAL k 77	None	0.88A	3elzB-4v1ak: undetectable	3elzB-4v1ak: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S8P_A_SAMA500_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	4v1a	MITORIBOSOMAL PROTEIN ML48, MRPL48 (Sus scrofa)	3 / 3	HIS k 153 SER k 105 GLU k 104	None	0.81A	3s8pA-4v1ak: undetectable	3s8pA-4v1ak: 22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DB5_A_CYSA503_0 (CYSTEINE DESULFURASE)	4v1a	MITORIBOSOMAL PROTEIN ML48, MRPL48 (Sus scrofa)	4 / 8	ALA k 126 ARG k 155 HIS k 153 THR k 129	None	1.27A	5db5A-4v1ak: undetectable 5db5B-4v1ak: undetectable	5db5A-4v1ak: 20.34 5db5B-4v1ak: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JQ7_B_T0RB705_1 (ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1 ENVELOPE GLYCOPROTEIN 2)	4v1a	MITORIBOSOMAL PROTEIN ML48, MRPL48 (Sus scrofa)	4 / 7	VAL k 186 LEU k 184 GLU k 188 LEU k 162	None	0.68A	5jq7A-4v1ak: undetectable	5jq7A-4v1ak: 20.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ELZ_B_CHDB152_0","ILEAL BILE ACID-BINDING PROTEIN","4v1a","MITORIBOSOMAL PROTEIN ML48, MRPL48","Sus scrofa",3,"ASN k  92;HIS k 189;VAL k  77","None","0.88A","3elzB-4v1ak:undetectable","3elzB-4v1ak:22.58"],["3S8P_A_SAMA500_1","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","4v1a","MITORIBOSOMAL PROTEIN ML48, MRPL48","Sus scrofa",3,"HIS k 153;SER k 105;GLU k 104","None","0.81A","3s8pA-4v1ak:undetectable","3s8pA-4v1ak:22.26"],["5DB5_A_CYSA503_0","CYSTEINE DESULFURASE","4v1a","MITORIBOSOMAL PROTEIN ML48, MRPL48","Sus scrofa",4,"ALA k 126;ARG k 155;HIS k 153;THR k 129","None","1.27A","5db5A-4v1ak:undetectable;5db5B-4v1ak:undetectable","5db5A-4v1ak:20.34;5db5B-4v1ak:20.34"],["5JQ7_B_T0RB705_1","ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1,ENVELOPE GLYCOPROTEIN 1;ENVELOPE GLYCOPROTEIN 2","4v1a","MITORIBOSOMAL PROTEIN ML48, MRPL48","Sus scrofa",4,"VAL k 186;LEU k 184;GLU k 188;LEU k 162","None","0.68A","5jq7A-4v1ak:undetectable","5jq7A-4v1ak:20.82"]]