SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4v1l CARBOHYDRATE BINDING
MODULE
(Ruminococcus
flavefaciens) 		5 / 12 ILE A 499
ILE A 570
ILE A 526
ILE A 532
ILE A 593
 None
GOL  A1627 (-4.6A)
None
None
None
 0.93A 1oipA-4v1lA:
undetectable		 1oipA-4v1lA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4v1l CARBOHYDRATE BINDING
MODULE
(Ruminococcus
flavefaciens) 		3 / 3 ARG A 515
VAL A 549
TRP A 607
 GOL  A1626 ( 4.8A)
None
None
 1.05A 1qw6A-4v1lA:
undetectable		 1qw6A-4v1lA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4v1l CARBOHYDRATE BINDING
MODULE
(Ruminococcus
flavefaciens) 		3 / 3 ARG A 515
VAL A 549
TRP A 607
 GOL  A1626 ( 4.8A)
None
None
 1.04A 1qwcA-4v1lA:
undetectable		 1qwcA-4v1lA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4v1l CARBOHYDRATE BINDING
MODULE
(Ruminococcus
flavefaciens) 		3 / 3 ARG A 515
VAL A 549
TRP A 607
 GOL  A1626 ( 4.8A)
None
None
 1.02A 1vagA-4v1lA:
undetectable		 1vagA-4v1lA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4v1l CARBOHYDRATE BINDING
MODULE
(Ruminococcus
flavefaciens) 		3 / 3 ARG A 515
VAL A 549
TRP A 607
 GOL  A1626 ( 4.8A)
None
None
 1.04A 1zviA-4v1lA:
undetectable		 1zviA-4v1lA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4v1l CARBOHYDRATE BINDING
MODULE
(Ruminococcus
flavefaciens) 		3 / 3 ARG A 515
VAL A 549
TRP A 607
 GOL  A1626 ( 4.8A)
None
None
 0.99A 5fvoA-4v1lA:
undetectable		 5fvoA-4v1lA:
16.80