SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v1u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 7 LEU A 305
THR A 179
TRP A 180
ASN A 170
 None
 1.10A 1afsA-4v1uA:
undetectable		 1afsA-4v1uA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 7 LEU A 305
THR A 179
TRP A 180
ASN A 170
 None
 1.10A 1afsB-4v1uA:
undetectable		 1afsB-4v1uA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 VAL A 269
VAL A 105
TRP A  96
 None
 0.87A 1av2C-4v1uA:
undetectable
1av2D-4v1uA:
undetectable		 1av2C-4v1uA:
2.94
1av2D-4v1uA:
2.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 12 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
 None
 1.02A 1fm6A-4v1uA:
undetectable		 1fm6A-4v1uA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		6 / 12 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
LEU A 286
 None
 1.33A 1k74A-4v1uA:
undetectable		 1k74A-4v1uA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 7 LEU A 622
LEU A 597
GLY A 554
MET A 773
 None
 0.89A 1n13G-4v1uA:
0.0
1n13J-4v1uA:
0.5		 1n13G-4v1uA:
5.91
1n13J-4v1uA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 4 ILE A 372
ARG A 384
ASP A 649
ASN A 611
 None
 1.16A 1nbiD-4v1uA:
undetectable		 1nbiD-4v1uA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 ILE A 306
LEU A 305
VAL A 365
HIS A 209
GLN A 433
 None
 0.93A 1tw4A-4v1uA:
undetectable		 1tw4A-4v1uA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 VAL A 269
VAL A 105
TRP A  96
 None
 0.87A 1w5uC-4v1uA:
undetectable
1w5uD-4v1uA:
undetectable		 1w5uC-4v1uA:
2.94
1w5uD-4v1uA:
2.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 12 ILE A 264
GLN A 258
LEU A 134
ALA A 133
VAL A 195
 None
 1.13A 1xdkA-4v1uA:
undetectable		 1xdkA-4v1uA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 4v1u LYND
(Lyngbya
aestuarii) 		6 / 12 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
LEU A 286
 None
 1.24A 1xiuA-4v1uA:
undetectable		 1xiuA-4v1uA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 4v1u LYND
(Lyngbya
aestuarii) 		6 / 12 ILE A 264
ALA A 261
GLN A 258
LEU A 134
ALA A 133
LEU A 286
 None
 1.37A 1xiuA-4v1uA:
undetectable		 1xiuA-4v1uA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		6 / 12 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
LEU A 286
 None
 1.25A 1xlsA-4v1uA:
undetectable		 1xlsA-4v1uA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		6 / 12 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
LEU A 286
 None
 1.25A 1xlsB-4v1uA:
undetectable		 1xlsB-4v1uA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		6 / 12 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
LEU A 286
 None
 1.25A 1xlsC-4v1uA:
undetectable		 1xlsC-4v1uA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		6 / 12 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
LEU A 286
 None
 1.25A 1xlsD-4v1uA:
undetectable		 1xlsD-4v1uA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 6 TRP A 559
HIS A 672
THR A 771
PRO A 770
 None
 1.49A 2ez7A-4v1uA:
undetectable		 2ez7A-4v1uA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 VAL A 105
TRP A  96
VAL A 269
 None
 0.90A 2izqA-4v1uA:
undetectable
2izqB-4v1uA:
undetectable		 2izqA-4v1uA:
2.94
2izqB-4v1uA:
2.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 ASN A 294
LEU A 293
HIS A 295
 None
 0.72A 2q6fB-4v1uA:
undetectable		 2q6fB-4v1uA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 6 LEU A 358
TYR A 355
ILE A 306
ILE A 725
 None
 0.97A 2q8hA-4v1uA:
undetectable		 2q8hA-4v1uA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 4v1u LYND
PATE
(Lyngbya
aestuarii;
uncultured
Prochloron
sp.) 		5 / 12 LEU A  25
PHE A  13
LEU A  43
LEU C  29
VAL A  71
 None
 1.36A 2qd4B-4v1uA:
3.6		 2qd4B-4v1uA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 8 MET A 773
LEU A 622
LEU A 597
GLY A 554
 None
 0.90A 2qqdB-4v1uA:
undetectable
2qqdC-4v1uA:
undetectable		 2qqdB-4v1uA:
9.26
2qqdC-4v1uA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 GLN A 172
THR A 313
TRP A 204
 None
 1.12A 2rctA-4v1uA:
undetectable		 2rctA-4v1uA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 8 ALA A 392
GLY A 213
SER A 220
ALA A 219
 None
 0.76A 2vh3B-4v1uA:
undetectable		 2vh3B-4v1uA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 SER A 309
ARG A 308
GLN A 310
 None
 0.91A 2xnrA-4v1uA:
undetectable		 2xnrA-4v1uA:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 5 TYR A 585
GLU A 647
ASP A 649
ASP A 653
 None
 1.32A 2yqzA-4v1uA:
2.5		 2yqzA-4v1uA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 5 TYR A 585
GLU A 647
ASP A 649
ASP A 653
 None
 1.30A 2yqzB-4v1uA:
undetectable		 2yqzB-4v1uA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 GLN A 643
GLU A 640
THR A 639
ARG A 384
GLY A 420
 None
CA  A1777 (-2.7A)
None
None
None
 1.49A 3abmA-4v1uA:
undetectable
3abmB-4v1uA:
undetectable
3abmT-4v1uA:
undetectable		 3abmA-4v1uA:
22.14
3abmB-4v1uA:
14.64
3abmT-4v1uA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 10 GLN A 643
GLU A 640
THR A 639
ARG A 384
GLY A 420
 None
CA  A1777 (-2.7A)
None
None
None
 1.41A 3ag2A-4v1uA:
0.0
3ag2B-4v1uA:
0.0
3ag2T-4v1uA:
0.0		 3ag2A-4v1uA:
22.14
3ag2B-4v1uA:
14.64
3ag2T-4v1uA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 12 GLN A 643
GLU A 640
THR A 639
ARG A 384
GLY A 420
 None
CA  A1777 (-2.7A)
None
None
None
 1.43A 3ag4A-4v1uA:
undetectable
3ag4B-4v1uA:
undetectable
3ag4T-4v1uA:
undetectable		 3ag4A-4v1uA:
22.14
3ag4B-4v1uA:
14.64
3ag4T-4v1uA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 12 ILE A 264
GLN A 258
LEU A 134
ALA A 133
LEU A 286
 None
 1.00A 3dzyA-4v1uA:
undetectable		 3dzyA-4v1uA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 10 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
 None
 1.06A 3falC-4v1uA:
undetectable		 3falC-4v1uA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 8 SER A 360
LEU A 182
PRO A 194
TRP A 204
 None
 1.18A 3jq7B-4v1uA:
undetectable		 3jq7B-4v1uA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 ASP A 724
ARG A 210
ARG A 323
 None
 0.95A 3k37A-4v1uA:
undetectable		 3k37A-4v1uA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 VAL A 269
VAL A 105
TRP A  96
 None
 0.90A 3l8lC-4v1uA:
undetectable
3l8lD-4v1uA:
undetectable		 3l8lC-4v1uA:
2.94
3l8lD-4v1uA:
2.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 7 ASN A 574
GLU A 575
GLN A 582
TYR A 577
 None
 1.26A 3ugrA-4v1uA:
undetectable		 3ugrA-4v1uA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 LYS A 731
ARG A 743
LEU A 511
 None
 1.24A 3v4tE-4v1uA:
undetectable		 3v4tE-4v1uA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 6 TYR A 161
ASP A 159
GLN A 163
GLU A 124
 None
 1.37A 4azvA-4v1uA:
undetectable		 4azvA-4v1uA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 LYS A 409
THR A 639
ILE A 634
 AMP  A 777 (-2.9A)
None
None
 0.77A 4e0fB-4v1uA:
undetectable		 4e0fB-4v1uA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 ILE A 603
ALA A 626
GLY A 625
GLY A 531
ASN A 530
 None
 1.28A 4e47B-4v1uA:
undetectable		 4e47B-4v1uA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 7 TRP A 559
GLY A 623
GLY A 608
GLU A 640
 None
None
None
CA  A1777 (-2.7A)
 1.06A 4fgkB-4v1uA:
3.4		 4fgkB-4v1uA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 GLN A 336
THR A 346
THR A 347
 None
 0.72A 4fu9A-4v1uA:
undetectable		 4fu9A-4v1uA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 GLN A 336
THR A 346
THR A 347
 None
 0.70A 4fufA-4v1uA:
undetectable		 4fufA-4v1uA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 ILE A 264
GLN A 258
LEU A 134
ALA A 133
LEU A 286
 None
 1.01A 4nqaA-4v1uA:
undetectable		 4nqaA-4v1uA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 ILE A 264
GLN A 258
LEU A 134
ALA A 133
VAL A 195
 None
 1.14A 4nqaA-4v1uA:
undetectable		 4nqaA-4v1uA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 4v1u LYND
PATE
(Lyngbya
aestuarii;
uncultured
Prochloron
sp.) 		5 / 12 HIS A  32
ALA C  33
PHE A  13
GLN A  10
GLY A 100
 None
 1.01A 4uilH-4v1uA:
undetectable
4uilL-4v1uA:
undetectable		 4uilH-4v1uA:
16.53
4uilL-4v1uA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 LEU A  34
GLU A  73
ALA A  76
LEU A  75
TYR A  80
 None
 1.07A 4wg0J-4v1uA:
undetectable
4wg0K-4v1uA:
undetectable
4wg0L-4v1uA:
undetectable		 4wg0J-4v1uA:
1.99
4wg0K-4v1uA:
1.99
4wg0L-4v1uA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4v1u LYND
PATE
(Lyngbya
aestuarii;
uncultured
Prochloron
sp.) 		5 / 10 ALA C  33
GLU C  32
LEU C  34
GLY A  27
HIS A  12
 None
 1.41A 5dxbA-4v1uC:
undetectable		 5dxbA-4v1uC:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 ILE A 264
GLN A 258
LEU A 134
ALA A 133
LEU A 286
 None
 1.04A 5ji0A-4v1uA:
undetectable		 5ji0A-4v1uA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 ILE A 264
GLN A 258
LEU A 134
ALA A 133
VAL A 195
 None
 1.16A 5ji0A-4v1uA:
undetectable		 5ji0A-4v1uA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA613_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 4 ASP A 299
LYS A 301
THR A 292
PRO A 361
 None
 1.16A 5jwaA-4v1uA:
0.0		 5jwaA-4v1uA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4v1u LYND
(Lyngbya
aestuarii) 		3 / 3 GLY A 364
THR A 367
ASN A 214
 None
 0.67A 5odiG-4v1uA:
3.7		 5odiG-4v1uA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 4 VAL A 641
VAL A 638
TYR A 585
GLN A 582
 None
 1.40A 5qggA-4v1uA:
undetectable		 5qggA-4v1uA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 4 VAL A 641
VAL A 638
TYR A 585
GLN A 582
 None
 1.36A 5qgoA-4v1uA:
undetectable		 5qgoA-4v1uA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 4 VAL A 641
VAL A 638
TYR A 585
GLN A 582
 None
 1.39A 5qgpA-4v1uA:
undetectable		 5qgpA-4v1uA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 4 VAL A 641
VAL A 638
TYR A 585
GLN A 582
 None
 1.45A 5qgqA-4v1uA:
undetectable		 5qgqA-4v1uA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4v1u LYND
(Lyngbya
aestuarii) 		4 / 4 VAL A 641
VAL A 638
TYR A 585
GLN A 582
 None
 1.40A 5qhbA-4v1uA:
undetectable		 5qhbA-4v1uA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 12 LEU A 157
LEU A 182
LEU A 181
ILE A 291
LEU A 286
 None
 1.14A 5toaB-4v1uA:
undetectable		 5toaB-4v1uA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		6 / 12 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
LEU A 286
 None
 1.18A 5uanA-4v1uA:
undetectable		 5uanA-4v1uA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 12 ALA A 247
GLY A 187
SER A 188
ASP A 160
TYR A 161
 None
 1.34A 5vlmF-4v1uA:
undetectable		 5vlmF-4v1uA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 ARG A 384
GLY A 420
GLN A 643
GLU A 640
THR A 639
 None
None
None
CA  A1777 (-2.7A)
None
 1.38A 5x1bG-4v1uA:
undetectable
5x1bN-4v1uA:
undetectable
5x1bO-4v1uA:
undetectable		 5x1bG-4v1uA:
7.48
5x1bN-4v1uA:
22.14
5x1bO-4v1uA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 11 ARG A 384
GLY A 420
GLN A 643
GLU A 640
THR A 639
 None
None
None
CA  A1777 (-2.7A)
None
 1.39A 5x1fG-4v1uA:
undetectable
5x1fN-4v1uA:
undetectable
5x1fO-4v1uA:
undetectable		 5x1fG-4v1uA:
7.48
5x1fN-4v1uA:
22.14
5x1fO-4v1uA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4v1u LYND
(Lyngbya
aestuarii) 		6 / 12 ILE A 264
ALA A 261
ALA A 260
LEU A 134
ALA A 133
LEU A 286
 None
 1.26A 5z12B-4v1uA:
undetectable		 5z12B-4v1uA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4v1u LYND
(Lyngbya
aestuarii) 		5 / 12 THR A 126
ILE A 139
VAL A 141
VAL A 114
ILE A 264
 None
 0.99A 6emuB-4v1uA:
undetectable		 6emuB-4v1uA:
12.71