SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v1y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 HIS A  66
HIS A  68
HIS A 243
GLU A 246
HIS A 276
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
FE  A 481 (-2.8A)
 0.61A 1a4lA-4v1yA:
22.0		 1a4lA-4v1yA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 HIS A  68
LEU A  88
HIS A 243
GLU A 246
HIS A 276
ASP A 327
 FE  A 481 (-3.9A)
None
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
FE  A 481 (-2.8A)
 0.65A 1a4lB-4v1yA:
22.0		 1a4lB-4v1yA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 HIS A  66
HIS A  68
HIS A 243
GLU A 246
HIS A 276
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
FE  A 481 (-2.8A)
 0.61A 1a4lC-4v1yA:
22.0		 1a4lC-4v1yA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  66
HIS A 243
PHE A 157
HIS A  68
GLU A 125
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
None
FE  A 481 (-3.9A)
None
 1.29A 1a4lC-4v1yA:
22.0		 1a4lC-4v1yA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  68
HIS A 243
GLU A 246
HIS A 276
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
FE  A 481 (-2.8A)
 0.57A 1a4lD-4v1yA:
22.0		 1a4lD-4v1yA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 ALA A 115
THR A 326
THR A  67
ILE A 123
 None
 0.79A 1c9sI-4v1yA:
undetectable
1c9sJ-4v1yA:
undetectable		 1c9sI-4v1yA:
10.51
1c9sJ-4v1yA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 ALA A 115
THR A 326
THR A  67
ILE A 123
 None
 0.77A 1c9sU-4v1yA:
undetectable
1c9sV-4v1yA:
undetectable		 1c9sU-4v1yA:
10.51
1c9sV-4v1yA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 4 ARG A 109
ALA A 105
ALA A 141
GLU A 145
 None
 0.97A 1e7bA-4v1yA:
undetectable		 1e7bA-4v1yA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 4 ARG A 109
ALA A 105
ALA A 141
GLU A 145
 None
 0.97A 1e7bB-4v1yA:
undetectable		 1e7bB-4v1yA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 5 ARG A 109
ALA A 105
ALA A 141
GLU A 145
 None
 1.00A 1e7cA-4v1yA:
undetectable		 1e7cA-4v1yA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 VAL A  58
LEU A  11
VAL A  28
ALA A 390
ILE A  33
 None
 0.87A 1epbB-4v1yA:
undetectable		 1epbB-4v1yA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 7 ALA A 115
THR A 326
THR A  67
ILE A 123
 None
 0.71A 1gtnA-4v1yA:
undetectable
1gtnK-4v1yA:
undetectable		 1gtnA-4v1yA:
10.51
1gtnK-4v1yA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 ALA A 115
THR A 326
THR A  67
ILE A 123
 None
 0.74A 1gtnE-4v1yA:
undetectable
1gtnF-4v1yA:
undetectable		 1gtnE-4v1yA:
10.51
1gtnF-4v1yA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 GLY A 382
SER A 383
ILE A  33
ILE A 393
LEU A 392
 None
 1.17A 1kyvA-4v1yA:
undetectable
1kyvE-4v1yA:
undetectable		 1kyvA-4v1yA:
16.17
1kyvE-4v1yA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 393
LEU A 392
GLY A 382
SER A 383
ILE A  33
 None
 1.18A 1kyvB-4v1yA:
undetectable
1kyvC-4v1yA:
undetectable		 1kyvB-4v1yA:
16.17
1kyvC-4v1yA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 TRP A  25
VAL A  43
PRO A  44
 None
 0.70A 1rg1A-4v1yA:
2.2		 1rg1A-4v1yA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 TRP A  25
VAL A  43
PRO A  44
 None
 0.70A 1rh0A-4v1yA:
1.9		 1rh0A-4v1yA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 ALA A 115
THR A 326
THR A  67
ILE A 123
 None
 0.76A 1utdI-4v1yA:
undetectable
1utdJ-4v1yA:
undetectable		 1utdI-4v1yA:
10.51
1utdJ-4v1yA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AXN_A_EDTA737_0
(6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
PHOSPHATASE 3
(6PF-2-K/FRU-
2,6-P2ASE
BRAIN/PLACENTA-TYPE
ISOZYME) (IPFK-2)
[INCLUDES: 6-
PHOSPHOFRUCTO-2-KINA
SE (EC 2.7.1.105)
FRUCTOSE-2,6-BISPHO
SPHATASE (EC
3.1.3.46)])		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 THR A 241
ASN A 126
PHE A  84
ALA A 216
THR A 217
 None
 1.30A 2axnA-4v1yA:
1.8		 2axnA-4v1yA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 7 SER A 301
ASP A 327
SER A 331
GLN A  83
 None
FE  A 481 (-2.8A)
None
None
 1.05A 2cmlA-4v1yA:
undetectable		 2cmlA-4v1yA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 SER A 301
ASP A 327
SER A 331
GLN A  83
 None
FE  A 481 (-2.8A)
None
None
 1.03A 2cmlB-4v1yA:
undetectable		 2cmlB-4v1yA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 10 LEU A 392
GLY A  61
LEU A  59
LEU A  11
ILE A 384
 None
 1.10A 2f8dA-4v1yA:
undetectable		 2f8dA-4v1yA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 10 LEU A 392
GLY A  61
LEU A  59
LEU A  11
ILE A 384
 None
 1.07A 2f8dB-4v1yA:
undetectable		 2f8dB-4v1yA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 6 LEU A 267
MET A 226
LEU A 242
MET A 262
 None
 1.17A 2kuhA-4v1yA:
undetectable		 2kuhA-4v1yA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 HIS A  68
HIS A  66
HIS A 243
 FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
 0.50A 2ozrF-4v1yA:
undetectable		 2ozrF-4v1yA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 HIS A  68
HIS A 243
GLU A 246
HIS A 276
SER A 301
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
None
FE  A 481 (-2.8A)
 0.56A 2pgfA-4v1yA:
21.6		 2pgfA-4v1yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 HIS A  66
HIS A  68
HIS A 243
GLU A 246
HIS A 276
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
FE  A 481 (-2.8A)
 0.52A 2pgrA-4v1yA:
21.8		 2pgrA-4v1yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A 243
HIS A 276
GLY A 325
HIS A  66
HIS A  68
 FE  A 481 (-4.1A)
FE  A 481 (-3.9A)
None
FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
 1.16A 2pgrA-4v1yA:
21.8		 2pgrA-4v1yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 ASP A 327
HIS A 276
SER A 307
LEU A 305
 FE  A 481 (-2.8A)
FE  A 481 (-3.9A)
None
None
 0.96A 2q0iA-4v1yA:
undetectable		 2q0iA-4v1yA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A  51
LEU A 425
VAL A  58
THR A  13
ILE A  33
 None
 1.16A 2vn0A-4v1yA:
undetectable		 2vn0A-4v1yA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 9 ILE A 384
GLY A 382
ILE A  63
VAL A 424
ILE A 393
 None
 1.19A 3ekyB-4v1yA:
undetectable		 3ekyB-4v1yA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 10 ASP A 427
VAL A 431
GLY A 144
ILE A 209
THR A 121
 None
 1.15A 3el5A-4v1yA:
undetectable		 3el5A-4v1yA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 GLN A 298
ASN A  64
VAL A 151
GLN A 273
THR A 241
 None
 1.38A 3em0A-4v1yA:
undetectable		 3em0A-4v1yA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 6 ILE A 384
VAL A  58
LEU A 394
LEU A 425
 None
 0.92A 3kp6A-4v1yA:
0.7
3kp6B-4v1yA:
0.4		 3kp6A-4v1yA:
13.74
3kp6B-4v1yA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 HIS A  68
HIS A  66
HIS A 243
 FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
 0.61A 3qpkA-4v1yA:
undetectable		 3qpkA-4v1yA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 HIS A 243
HIS A  66
HIS A  68
 FE  A 481 (-4.1A)
FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
 0.61A 3qpkA-4v1yA:
undetectable		 3qpkA-4v1yA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 HIS A  68
HIS A  66
HIS A 243
 FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
 0.59A 3qpkB-4v1yA:
undetectable		 3qpkB-4v1yA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 5 ALA A 153
GLU A 125
ALA A 130
MET A 140
 None
 1.21A 3r9tC-4v1yA:
undetectable		 3r9tC-4v1yA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.96A 3uboB-4v1yA:
3.4		 3uboB-4v1yA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 GLN A  71
HIS A 243
GLU A 246
HIS A 276
SER A 301
 None
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
None
 0.91A 4aqlA-4v1yA:
41.0		 4aqlA-4v1yA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 GLU A 246
ALA A 220
HIS A 276
SER A 301
ASP A 327
 FE  A 481 ( 4.3A)
None
FE  A 481 (-3.9A)
None
FE  A 481 (-2.8A)
 1.28A 4aqlA-4v1yA:
41.0		 4aqlA-4v1yA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 LEU A  88
HIS A 243
GLU A 246
HIS A 276
SER A 301
ASP A 327
 None
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
None
FE  A 481 (-2.8A)
 0.69A 4aqlA-4v1yA:
41.0		 4aqlA-4v1yA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 10 HIS A 276
HIS A  66
ASP A 327
HIS A 243
ASN A 126
 FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
FE  A 481 (-2.8A)
FE  A 481 (-4.1A)
None
 1.08A 4c1dB-4v1yA:
undetectable		 4c1dB-4v1yA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 6 TYR A  93
HIS A  68
HIS A 243
TYR A  85
 None
FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
None
 1.30A 4df2A-4v1yA:
7.9		 4df2A-4v1yA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.96A 4e3aA-4v1yA:
3.5		 4e3aA-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 4 HIS A  66
HIS A  68
HIS A 276
HIS A 243
 FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
 1.09A 4ef3A-4v1yA:
undetectable		 4ef3A-4v1yA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 8 ASP A 340
ASN A 332
GLU A 114
ASP A 327
 None
None
None
FE  A 481 (-2.8A)
 1.19A 4gkiC-4v1yA:
undetectable		 4gkiC-4v1yA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.95A 4k8pA-4v1yA:
2.3		 4k8pA-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.96A 4k8pB-4v1yA:
3.3		 4k8pB-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.95A 4k8tA-4v1yA:
2.7		 4k8tA-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.95A 4k8tB-4v1yA:
3.2		 4k8tB-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.95A 4k93A-4v1yA:
2.8		 4k93A-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.94A 4k93B-4v1yA:
2.9		 4k93B-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.97A 4k9cA-4v1yA:
2.3		 4k9cA-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.95A 4k9cB-4v1yA:
3.2		 4k9cB-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.98A 4k9iB-4v1yA:
3.2		 4k9iB-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.97A 4kadB-4v1yA:
2.7		 4kadB-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 GLU A 263
ARG A 290
HIS A 291
 None
 0.75A 4kf9A-4v1yA:
undetectable		 4kf9A-4v1yA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.97A 4lc4A-4v1yA:
3.2		 4lc4A-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A 338
GLY A 339
SER A 118
LEU A 395
THR A 326
 None
 0.97A 4lc4B-4v1yA:
3.0		 4lc4B-4v1yA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A  51
LEU A 364
GLY A  61
ILE A 393
ASN A 429
 None
 1.14A 4o1eA-4v1yA:
5.9		 4o1eA-4v1yA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 ILE A  51
LEU A 364
GLY A  61
ILE A 393
ASN A 429
 None
 1.15A 4o1eB-4v1yA:
5.9		 4o1eB-4v1yA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 5 THR A 219
THR A 217
ASP A 250
TYR A  85
 None
 1.44A 4oltA-4v1yA:
undetectable		 4oltA-4v1yA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 5 THR A 219
THR A 217
ASP A 250
TYR A  85
 None
 1.41A 4oltB-4v1yA:
undetectable		 4oltB-4v1yA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 5 THR A 219
THR A 217
ASP A 250
TYR A  85
 None
 1.43A 4qwpA-4v1yA:
undetectable		 4qwpA-4v1yA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 5 THR A 219
THR A 217
ASP A 250
TYR A  85
 None
 1.44A 4qwpB-4v1yA:
undetectable		 4qwpB-4v1yA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 7 ARG A 149
THR A 121
GLY A  61
THR A 122
 None
 0.98A 4qwpB-4v1yA:
undetectable		 4qwpB-4v1yA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  68
HIS A 243
HIS A 276
LEU A 305
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 (-3.9A)
None
FE  A 481 (-2.8A)
 0.35A 4r88A-4v1yA:
32.0		 4r88A-4v1yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  68
HIS A 243
GLU A 246
LEU A 305
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
None
FE  A 481 (-2.8A)
 0.40A 4r88B-4v1yA:
32.8		 4r88B-4v1yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  68
HIS A 243
GLU A 246
LEU A 305
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
None
FE  A 481 (-2.8A)
 0.40A 4r88C-4v1yA:
32.4		 4r88C-4v1yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  68
HIS A 243
GLU A 246
LEU A 305
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
None
FE  A 481 (-2.8A)
 0.41A 4r88D-4v1yA:
32.4		 4r88D-4v1yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  68
HIS A 243
GLU A 246
LEU A 305
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
None
FE  A 481 (-2.8A)
 0.42A 4r88E-4v1yA:
32.1		 4r88E-4v1yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  68
HIS A 243
GLU A 246
LEU A 305
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
None
FE  A 481 (-2.8A)
 0.46A 4r88F-4v1yA:
32.4		 4r88F-4v1yA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 11 VAL A 424
ILE A 393
ALA A 416
ILE A 412
PHE A  62
 None
 1.17A 5d75A-4v1yA:
undetectable		 5d75A-4v1yA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 9 ILE A 338
GLY A 119
THR A 121
GLN A 415
LEU A  59
 None
 1.45A 5fhzB-4v1yA:
undetectable		 5fhzB-4v1yA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 TYR A 111
THR A 241
ALA A 115
SER A 210
ILE A 209
 None
 1.17A 5iwuA-4v1yA:
undetectable		 5iwuA-4v1yA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		3 / 3 HIS A 243
HIS A  66
HIS A  68
 FE  A 481 (-4.1A)
FE  A 481 (-3.9A)
FE  A 481 (-3.9A)
 0.56A 5migA-4v1yA:
undetectable		 5migA-4v1yA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 6 THR A 219
ARG A 159
ASP A 158
GLY A 225
 None
 1.24A 5mraA-4v1yA:
undetectable
5mraB-4v1yA:
undetectable		 5mraA-4v1yA:
14.97
5mraB-4v1yA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		4 / 5 GLN A 200
ASP A 199
SER A 198
ARG A 236
 None
 1.50A 5w4zA-4v1yA:
4.8		 5w4zA-4v1yA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 LEU A 408
HIS A 405
VAL A 424
ASP A 396
ASP A 422
 None
 1.43A 6bxnA-4v1yA:
undetectable		 6bxnA-4v1yA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		6 / 12 HIS A  68
LEU A  88
HIS A 243
GLU A 246
HIS A 276
ASP A 327
 FE  A 481 (-3.9A)
None
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
FE  A 481 (-2.8A)
 0.81A 6n91A-4v1yA:
22.9		 6n91A-4v1yA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  68
HIS A 243
GLU A 246
HIS A 276
ASP A 327
 FE  A 481 (-3.9A)
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
FE  A 481 (-2.8A)
 0.66A 6n91B-4v1yA:
22.8		 6n91B-4v1yA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 4v1y ATRAZINE
CHLOROHYDROLASE
(Pseudomonas
sp.
ADP) 		5 / 12 HIS A  68
LEU A  88
HIS A 243
GLU A 246
HIS A 276
 FE  A 481 (-3.9A)
None
FE  A 481 (-4.1A)
FE  A 481 ( 4.3A)
FE  A 481 (-3.9A)
 0.81A 6n91B-4v1yA:
22.8		 6n91B-4v1yA:
10.88