SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 9 LEU A 288
LYS A 287
ILE A 291
VAL A 254
GLN A 262
 None
 1.46A 1gx8A-4v33A:
undetectable		 1gx8A-4v33A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 11 LEU A 245
ALA A 230
VAL A 239
MET A 261
LEU A 288
 None
 1.34A 1kt6A-4v33A:
undetectable		 1kt6A-4v33A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 11 LEU A 245
ALA A 230
VAL A 239
MET A 261
LEU A 288
 None
 1.33A 1kt7A-4v33A:
undetectable		 1kt7A-4v33A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		4 / 7 GLU A 111
GLN A 118
ALA A 121
ILE A  49
 None
 0.84A 2xkwA-4v33A:
undetectable		 2xkwA-4v33A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		4 / 8 ASN A 197
THR A 183
LEU A 185
ARG A 189
 None
EDO  A1365 (-4.5A)
None
None
 1.10A 3kp2A-4v33A:
undetectable
3kp2B-4v33A:
undetectable		 3kp2A-4v33A:
17.36
3kp2B-4v33A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		4 / 8 ASN A 197
THR A 183
LEU A 185
ARG A 189
 None
EDO  A1365 (-4.5A)
None
None
 1.00A 3kp6A-4v33A:
undetectable		 3kp6A-4v33A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		3 / 3 PRO A 104
SER A 102
ASN A  52
 None
 0.86A 3lslG-4v33A:
undetectable		 3lslG-4v33A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		4 / 7 MET A 261
LEU A 288
LEU A 245
PHE A 259
 None
 1.27A 3nk2X-4v33A:
undetectable		 3nk2X-4v33A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 10 PHE A 204
ASN A 213
PHE A 170
ILE A 258
PHE A 259
 None
 1.50A 3t3qA-4v33A:
undetectable		 3t3qA-4v33A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 10 PHE A 204
ASN A 213
PHE A 170
ILE A 258
PHE A 259
 None
 1.43A 3t3qB-4v33A:
undetectable		 3t3qB-4v33A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 10 PHE A 204
ASN A 213
PHE A 170
ILE A 258
PHE A 259
 None
 1.46A 3t3qC-4v33A:
undetectable		 3t3qC-4v33A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 10 PHE A 204
ASN A 213
PHE A 170
ILE A 258
PHE A 259
 None
 1.44A 3t3qD-4v33A:
undetectable		 3t3qD-4v33A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		4 / 6 SER A 263
TYR A 318
THR A 322
THR A 323
 None
 0.84A 3tneA-4v33A:
undetectable		 3tneA-4v33A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		4 / 7 SER A 263
TYR A 318
THR A 322
THR A 323
 None
 0.89A 3tneB-4v33A:
undetectable		 3tneB-4v33A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		4 / 6 MET A 174
LEU A 177
PRO A 145
TYR A 182
 None
None
None
ACT  A1363 ( 4.4A)
 1.25A 3vkxA-4v33A:
undetectable		 3vkxA-4v33A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 12 ASN A 197
THR A 183
LEU A 185
GLN A 118
ARG A 189
 None
EDO  A1365 (-4.5A)
None
None
None
 1.15A 4ejwA-4v33A:
undetectable		 4ejwA-4v33A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 12 ALA A  89
PHE A 105
ILE A  79
GLN A 118
PHE A 110
 None
 1.06A 5hgcA-4v33A:
undetectable		 5hgcA-4v33A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 12 ALA A  89
PHE A 105
LYS A  78
ILE A  79
PHE A 110
 None
 1.09A 5hgcA-4v33A:
undetectable		 5hgcA-4v33A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 6 ASP A 205
ASP A 206
HIS A 264
HIS A 268
HIS A 150
 ACT  A1361 (-3.5A)
ZN  A1362 (-2.7A)
ZN  A1362 ( 3.3A)
ZN  A1362 ( 3.3A)
ACT  A1361 (-4.0A)
 0.41A 5ncdA-4v33A:
10.2
5ncdD-4v33A:
3.8		 5ncdA-4v33A:
22.47
5ncdD-4v33A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 6 ASP A 205
ASP A 206
HIS A 264
HIS A 268
HIS A 150
 ACT  A1361 (-3.5A)
ZN  A1362 (-2.7A)
ZN  A1362 ( 3.3A)
ZN  A1362 ( 3.3A)
ACT  A1361 (-4.0A)
 0.37A 5ncdB-4v33A:
3.9
5ncdC-4v33A:
4.0		 5ncdB-4v33A:
22.47
5ncdC-4v33A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		4 / 4 ASP A 205
HIS A 264
HIS A 268
HIS A 150
 ACT  A1361 (-3.5A)
ZN  A1362 ( 3.3A)
ZN  A1362 ( 3.3A)
ACT  A1361 (-4.0A)
 0.31A 5ncdD-4v33A:
3.8		 5ncdD-4v33A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 8 ASP A 205
ASP A 206
HIS A 264
HIS A 268
HIS A 150
 ACT  A1361 (-3.5A)
ZN  A1362 (-2.7A)
ZN  A1362 ( 3.3A)
ZN  A1362 ( 3.3A)
ACT  A1361 (-4.0A)
 0.46A 5nekB-4v33A:
3.8		 5nekB-4v33A:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 8 ASP A 205
ASP A 206
HIS A 264
HIS A 268
HIS A 150
 ACT  A1361 (-3.5A)
ZN  A1362 (-2.7A)
ZN  A1362 ( 3.3A)
ZN  A1362 ( 3.3A)
ACT  A1361 (-4.0A)
 0.53A 5nekD-4v33A:
10.3		 5nekD-4v33A:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		5 / 6 ASP A 205
ASP A 206
HIS A 264
HIS A 268
HIS A 150
 ACT  A1361 (-3.5A)
ZN  A1362 (-2.7A)
ZN  A1362 ( 3.3A)
ZN  A1362 ( 3.3A)
ACT  A1361 (-4.0A)
 0.45A 5nelA-4v33A:
3.8
5nelD-4v33A:
3.9		 5nelA-4v33A:
22.47
5nelD-4v33A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		4 / 6 ASP A 205
HIS A 264
HIS A 268
HIS A 150
 ACT  A1361 (-3.5A)
ZN  A1362 ( 3.3A)
ZN  A1362 ( 3.3A)
ACT  A1361 (-4.0A)
 0.25A 5nelB-4v33A:
3.9
5nelC-4v33A:
3.8		 5nelB-4v33A:
22.47
5nelC-4v33A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		3 / 3 HIS A 150
ASP A 206
HIS A 264
 ACT  A1361 (-4.0A)
ZN  A1362 (-2.7A)
ZN  A1362 ( 3.3A)
 0.78A 5oexB-4v33A:
undetectable		 5oexB-4v33A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 4v33 POLYSACCHARIDE
DEACETYLASE-LIKE
PROTEIN
(Bacillus
anthracis) 		3 / 3 HIS A 150
ASP A 206
HIS A 264
 ACT  A1361 (-4.0A)
ZN  A1362 (-2.7A)
ZN  A1362 ( 3.3A)
 0.78A 5oexC-4v33A:
undetectable		 5oexC-4v33A:
22.43