SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v36'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 7 TYR A 620
ASP A 581
GLU A 613
PHE A 627
 None
 0.95A 1b2iA-4v36A:
undetectable		 1b2iA-4v36A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 7 THR A 842
LEU A 844
GLY A 846
LEU A 698
 None
None
None
LYN  A1851 ( 4.3A)
 1.04A 1gtiD-4v36A:
undetectable		 1gtiD-4v36A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		5 / 11 LEU A 826
LEU A 793
SER A 833
THR A 837
VAL A 841
 None
 1.26A 1ictA-4v36A:
undetectable
1ictC-4v36A:
undetectable		 1ictA-4v36A:
18.13
1ictC-4v36A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 8 ARG A 732
GLY A 823
GLY A 580
GLN A 611
 None
TRS  A1852 (-4.1A)
None
None
 0.79A 1jr1B-4v36A:
undetectable		 1jr1B-4v36A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 5 ASN A 544
ALA A 545
ASP A 581
GLU A 613
 None
 1.46A 1lqtA-4v36A:
undetectable
1lqtB-4v36A:
undetectable		 1lqtA-4v36A:
21.71
1lqtB-4v36A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 5 ASN A 544
ALA A 545
ASP A 581
GLU A 613
 None
 1.48A 1lquA-4v36A:
undetectable
1lquB-4v36A:
undetectable		 1lquA-4v36A:
21.71
1lquB-4v36A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 8 ARG A 742
GLN A 702
PHE A 701
ASN A 726
 LYN  A1851 (-4.3A)
None
None
None
 1.35A 1p6kA-4v36A:
undetectable		 1p6kA-4v36A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		5 / 10 ILE A 635
ALA A 634
ILE A 738
GLU A 735
ILE A 736
 None
 1.31A 2dm6A-4v36A:
undetectable
2dm6B-4v36A:
undetectable		 2dm6A-4v36A:
24.40
2dm6B-4v36A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 6 GLU A 668
PHE A 672
GLN A 669
PRO A 670
 None
 1.40A 2qqtA-4v36A:
undetectable		 2qqtA-4v36A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		5 / 12 PRO A 729
PHE A 756
ILE A 738
ASP A 739
PHE A 771
 None
None
None
LYN  A1851 (-4.0A)
None
 1.18A 2v95A-4v36A:
undetectable		 2v95A-4v36A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		3 / 3 MET A 617
VAL A 592
GLU A 586
 None
 0.91A 2x9gA-4v36A:
undetectable		 2x9gA-4v36A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		5 / 12 GLU A 668
VAL A 713
LEU A 680
GLN A 707
GLU A 679
 None
 1.06A 2ziaB-4v36A:
undetectable		 2ziaB-4v36A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		5 / 12 TYR A 559
LEU A 534
GLY A 526
VAL A 607
PHE A 609
 None
 1.29A 2zznA-4v36A:
undetectable		 2zznA-4v36A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 7 GLN A 611
LEU A 579
LEU A 549
LEU A 546
 None
 0.81A 3bgdB-4v36A:
1.8		 3bgdB-4v36A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 6 GLU A 668
PHE A 672
GLN A 669
PRO A 670
 None
 1.46A 3gclA-4v36A:
undetectable		 3gclA-4v36A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		5 / 9 LEU A 793
THR A 842
SER A 833
THR A 837
VAL A 841
 None
 1.30A 3ozkA-4v36A:
undetectable		 3ozkA-4v36A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		3 / 3 GLU A 668
PHE A 672
GLN A 669
 None
 0.97A 3r55A-4v36A:
undetectable		 3r55A-4v36A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		3 / 3 GLN A 611
GLU A 613
LYS A 824
 None
 0.96A 3su9A-4v36A:
undetectable		 3su9A-4v36A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 4 LEU A 778
ILE A 797
GLY A 631
PHE A 628
 None
 1.12A 4dc3A-4v36A:
undetectable		 4dc3A-4v36A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 7 ILE A 751
PRO A 748
GLY A 662
ALA A 754
 None
 0.93A 4g0uB-4v36A:
undetectable		 4g0uB-4v36A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 6 TYR A 828
VAL A 796
ILE A 797
LEU A 630
 None
 0.87A 4l1wB-4v36A:
undetectable		 4l1wB-4v36A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		5 / 12 GLN A 568
LEU A 579
ASN A 544
LEU A 552
GLY A 550
 None
 1.22A 4o5fA-4v36A:
undetectable
4o5fB-4v36A:
undetectable		 4o5fA-4v36A:
21.05
4o5fB-4v36A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		5 / 11 ALA A 570
VAL A 577
TYR A 610
GLY A 846
SER A 697
 None
 0.85A 4xnxA-4v36A:
undetectable		 4xnxA-4v36A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		5 / 12 ASN A 544
LEU A 552
GLY A 550
GLN A 568
LEU A 579
 None
 1.22A 5b8hA-4v36A:
undetectable
5b8hB-4v36A:
undetectable		 5b8hA-4v36A:
21.49
5b8hB-4v36A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 4v36 LYSYL-TRNA-DEPENDENT
L-YSYL-PHOSPHATIDYLG
YCEROL SYNTHASE
(Bacillus
licheniformis) 		4 / 4 VAL A 592
LEU A 619
ASN A 564
ASP A 562
 None
 1.28A 5vcyA-4v36A:
undetectable		 5vcyA-4v36A:
22.01