SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v3i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 4v3i VCA0115
(Vibrio
cholerae) 		4 / 7 THR A  44
LEU A  46
GLY A  48
LEU A 162
 None
 1.00A 1gtiD-4v3iA:
undetectable		 1gtiD-4v3iA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 4v3i VCA0115
(Vibrio
cholerae) 		4 / 7 PHE A 125
ILE A  70
TYR A  66
ARG A  67
 GOL  A1194 (-4.5A)
None
None
None
 1.44A 4o7gA-4v3iA:
undetectable
4o7gB-4v3iA:
undetectable		 4o7gA-4v3iA:
22.02
4o7gB-4v3iA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4v3i VCA0115
(Vibrio
cholerae) 		3 / 3 PRO A  45
LEU A  46
GLN A  68
 None
 0.59A 4pevB-4v3iA:
undetectable		 4pevB-4v3iA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 4v3i VCA0115
(Vibrio
cholerae) 		3 / 3 ASP A  34
ASN A  37
PHE A 155
 None
 0.75A 5dsgB-4v3iA:
undetectable		 5dsgB-4v3iA:
21.82