SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4v3l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 4v3l E3 UBIQUITIN-PROTEIN
LIGASE RNF38
(Homo
sapiens) 		4 / 5 CYH C 450
ILE C 452
HIS C 433
LEU C 429
 ZN  C1464 (-2.3A)
ZN  C1464 ( 4.8A)
ZN  C1464 (-3.1A)
None
 1.42A 3qpkA-4v3lC:
undetectable		 3qpkA-4v3lC:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4v3l E3 UBIQUITIN-PROTEIN
LIGASE RNF38
(Homo
sapiens) 		4 / 4 ALA C 437
VAL C 440
ASP C 441
LEU C 429
 None
 1.05A 4e7gA-4v3lC:
undetectable		 4e7gA-4v3lC:
11.41