SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4w2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 4w2q ANTI-MARBURGVIRUS
NUCLEOPROTEIN SINGLE
DOMAIN ANTIBODY C
NUCLEOPROTEIN
(Lama
glama;
Marburg
marburgvirus) 		4 / 6 ASP B 679
PHE A  29
GLU B 687
GLU A  97
 None
 1.24A 2dttB-4w2qB:
undetectable
2dttC-4w2qB:
undetectable		 2dttB-4w2qB:
16.24
2dttC-4w2qB:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 4w2q ANTI-MARBURGVIRUS
NUCLEOPROTEIN SINGLE
DOMAIN ANTIBODY C
NUCLEOPROTEIN
(Lama
glama;
Marburg
marburgvirus) 		3 / 3 SER B 658
HIS B 690
ASP A  98
 None
 0.80A 2wa2B-4w2qB:
undetectable		 2wa2B-4w2qB:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 4w2q ANTI-MARBURGVIRUS
NUCLEOPROTEIN SINGLE
DOMAIN ANTIBODY C
NUCLEOPROTEIN
(Lama
glama;
Marburg
marburgvirus) 		4 / 7 ASN B 669
LEU B 663
GLY A 101
TYR A 100
 None
 0.97A 4cp3A-4w2qB:
undetectable
4cp3B-4w2qB:
undetectable		 4cp3A-4w2qB:
20.72
4cp3B-4w2qB:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4w2q ANTI-MARBURGVIRUS
NUCLEOPROTEIN SINGLE
DOMAIN ANTIBODY C
(Lama
glama) 		5 / 12 TYR A  59
GLY A  60
LEU A  85
GLY A  10
LEU A  20
 None
 1.26A 4ze1A-4w2qA:
undetectable		 4ze1A-4w2qA:
12.87