SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4w5v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4w5v SUMO-ACTIVATING
ENZYME SUBUNIT 2
(Homo
sapiens) 		4 / 8 GLN B 524
GLN B 465
ASP B 479
SER B 493
 None
 1.18A 2xz5C-4w5vB:
undetectable
2xz5D-4w5vB:
undetectable		 2xz5C-4w5vB:
20.91
2xz5D-4w5vB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4w5v SUMO-ACTIVATING
ENZYME SUBUNIT 2
(Homo
sapiens) 		3 / 3 ARG B 512
ARG B 516
ASP B 484
 None
 1.00A 3wipG-4w5vB:
undetectable
3wipH-4w5vB:
undetectable		 3wipG-4w5vB:
21.40
3wipH-4w5vB:
21.40