SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4w79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 7 ILE A  64
ARG A 128
PHE A 196
PHE A 108
 None
 1.23A 1e71M-4w79A:
undetectable		 1e71M-4w79A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 7 ILE A  64
ARG A 128
PHE A 196
PHE A 108
 None
 1.20A 1e72M-4w79A:
undetectable		 1e72M-4w79A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 8 GLU A  30
SER A 144
LEU A 175
HIS A 148
 None
None
None
EDO  A 301 ( 4.6A)
 1.02A 2q0iA-4w79A:
undetectable		 2q0iA-4w79A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		3 / 3 TYR A  27
GLU A  29
ASN A 176
 None
None
EDO  A 301 (-4.3A)
 1.02A 2y7hC-4w79A:
undetectable		 2y7hC-4w79A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 7 TYR A 163
GLU A  29
TYR A 138
TYR A  80
 EDO  A 303 (-4.9A)
None
None
None
 1.37A 3ku9B-4w79A:
undetectable		 3ku9B-4w79A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 7 ASN A  31
LEU A  98
ASP A  99
SER A  25
 None
 1.02A 3lslA-4w79A:
undetectable
3lslD-4w79A:
undetectable		 3lslA-4w79A:
20.57
3lslD-4w79A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 5 VAL A 190
ILE A 133
MET A 173
ARG A 128
 None
 1.48A 3oezA-4w79A:
undetectable		 3oezA-4w79A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		5 / 11 LEU A 175
TYR A  80
VAL A  82
SER A  56
PHE A 142
 None
 1.40A 4lhmA-4w79A:
undetectable		 4lhmA-4w79A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 6 PHE A  94
SER A  15
PRO A 105
LEU A  84
 None
 1.22A 5dzka-4w79A:
undetectable
5dzko-4w79A:
undetectable		 5dzka-4w79A:
19.91
5dzko-4w79A:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 7 PHE A  94
SER A  15
ALA A  14
PRO A 105
 None
 0.97A 5dzkD-4w79A:
undetectable
5dzkR-4w79A:
undetectable		 5dzkD-4w79A:
19.91
5dzkR-4w79A:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 8 PHE A  94
SER A  15
ALA A  14
LEU A  84
 None
 0.98A 5dzkF-4w79A:
undetectable
5dzkT-4w79A:
undetectable		 5dzkF-4w79A:
19.91
5dzkT-4w79A:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4w79 PROTEIN N-TERMINAL
GLUTAMINE
AMIDOHYDROLASE
(Homo
sapiens) 		4 / 6 PHE A  94
SER A  15
ALA A  14
LEU A  84
 None
 1.05A 5dzkg-4w79A:
undetectable
5dzku-4w79A:
undetectable		 5dzkg-4w79A:
19.91
5dzku-4w79A:
2.35