SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4w7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 11 LEU A 263
VAL A   5
GLY A 275
TRP A 278
LEU A 308
 None
 1.18A 1lwcA-4w7vA:
undetectable		 1lwcA-4w7vA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w7v CELLULASE
(Xanthomonas
citri) 		4 / 6 LEU A 228
GLN A 229
LEU A 244
PHE A 247
 None
 1.09A 2einP-4w7vA:
undetectable
2einW-4w7vA:
undetectable		 2einP-4w7vA:
20.98
2einW-4w7vA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 4w7v CELLULASE
(Xanthomonas
citri) 		6 / 12 ASN A 133
GLU A 134
HIS A 204
TYR A 206
GLU A 246
TRP A 279
 None
CBI  A 401 (-2.8A)
None
CBI  A 401 (-4.5A)
None
CBI  A 402 (-4.2A)
 0.71A 2v3dA-4w7vA:
9.6		 2v3dA-4w7vA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 11 ASN A 133
GLU A 134
TYR A 206
GLU A 246
TRP A 279
 None
CBI  A 401 (-2.8A)
CBI  A 401 (-4.5A)
None
CBI  A 402 (-4.2A)
 0.78A 2v3dB-4w7vA:
2.7		 2v3dB-4w7vA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 11 GLY A 108
ALA A 107
ILE A 100
PRO A 135
LEU A  89
 None
 1.03A 4dt8A-4w7vA:
undetectable		 4dt8A-4w7vA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 10 GLY A 108
ALA A 107
ILE A 100
PRO A 135
LEU A  89
 None
 1.09A 4dt8B-4w7vA:
undetectable		 4dt8B-4w7vA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 4w7v CELLULASE
(Xanthomonas
citri) 		4 / 6 THR A 232
GLY A 230
TYR A 265
GLY A 224
 None
 0.76A 4fjpA-4w7vA:
undetectable		 4fjpA-4w7vA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4w7v CELLULASE
(Xanthomonas
citri) 		3 / 3 THR A 171
PRO A 135
THR A 168
 None
 0.87A 4hivD-4w7vA:
undetectable		 4hivD-4w7vA:
3.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4w7v CELLULASE
(Xanthomonas
citri) 		4 / 4 LYS A  18
ASN A  91
ASP A  88
ASP A  26
 None
 1.16A 4o1eB-4w7vA:
5.6		 4o1eB-4w7vA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 12 LEU A  85
VAL A   7
GLY A   6
LEU A   9
SER A  74
 None
 1.43A 4ot2A-4w7vA:
undetectable		 4ot2A-4w7vA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 4w7v CELLULASE
(Xanthomonas
citri) 		4 / 7 GLU A 202
THR A 277
GLY A 245
HIS A  90
 None
None
None
CBI  A 402 ( 4.7A)
 1.00A 4qwpB-4w7vA:
undetectable		 4qwpB-4w7vA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 9 ALA A 140
ALA A 144
ALA A 188
GLY A 137
ALA A 169
 None
 1.11A 5l5zK-4w7vA:
undetectable
5l5zL-4w7vA:
undetectable		 5l5zK-4w7vA:
22.85
5l5zL-4w7vA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 9 ALA A 140
ALA A 144
ALA A 188
GLY A 137
ALA A 169
 None
 1.11A 5l5zY-4w7vA:
undetectable
5l5zZ-4w7vA:
undetectable		 5l5zY-4w7vA:
22.85
5l5zZ-4w7vA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 9 ALA A 140
ALA A 169
GLY A 167
GLY A 172
SER A 178
 None
 1.04A 6bklE-4w7vA:
undetectable
6bklF-4w7vA:
undetectable
6bklG-4w7vA:
undetectable
6bklH-4w7vA:
undetectable		 6bklE-4w7vA:
5.42
6bklF-4w7vA:
5.42
6bklG-4w7vA:
5.42
6bklH-4w7vA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 10 LEU A 263
VAL A   5
GLY A 275
TRP A 278
LEU A 308
 None
 1.03A 6bsgA-4w7vA:
undetectable		 6bsgA-4w7vA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4w7v CELLULASE
(Xanthomonas
citri) 		5 / 12 LEU A 244
GLY A 245
HIS A 204
ARG A  47
ILE A  46
 None
 1.32A 6bxnB-4w7vA:
undetectable		 6bxnB-4w7vA:
21.95