SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4w87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		5 / 10 TYR A 316
THR A 112
ASN A 108
HIS A 314
HIS A 291
 None
 1.30A 1ivvA-4w87A:
undetectable		 1ivvA-4w87A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_B_DAHB382_1
(AMINE OXIDASE)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		5 / 10 TYR A 316
THR A 112
ASN A 108
HIS A 314
HIS A 291
 None
 1.33A 1ivvB-4w87A:
undetectable		 1ivvB-4w87A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.65A 1jnoA-4w87A:
undetectable		 1jnoA-4w87A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.65A 1jnoB-4w87A:
undetectable		 1jnoB-4w87A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.83A 1jo3A-4w87A:
undetectable		 1jo3A-4w87A:
4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.83A 1jo3B-4w87A:
undetectable		 1jo3B-4w87A:
4.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.81A 1jo4A-4w87A:
undetectable		 1jo4A-4w87A:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.82A 1jo4B-4w87A:
undetectable		 1jo4B-4w87A:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.68A 1magA-4w87A:
undetectable		 1magA-4w87A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.68A 1magB-4w87A:
undetectable		 1magB-4w87A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.67A 1ng8A-4w87A:
undetectable		 1ng8A-4w87A:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.67A 1ng8B-4w87A:
undetectable		 1ng8B-4w87A:
6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.91A 1nrmA-4w87A:
undetectable		 1nrmA-4w87A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.91A 1nrmB-4w87A:
undetectable		 1nrmB-4w87A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.76A 1nruA-4w87A:
undetectable		 1nruA-4w87A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 ALA A 115
VAL A 153
TRP A 171
 None
 0.76A 1nruB-4w87A:
undetectable		 1nruB-4w87A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		5 / 11 VAL A 179
ILE A 151
LEU A 191
LEU A 172
LEU A 222
 None
 1.28A 2a15A-4w87A:
undetectable		 2a15A-4w87A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		4 / 8 TYR A 229
ARG A 174
GLU A 177
VAL A 153
 None
 1.05A 2fl5E-4w87A:
undetectable
2fl5F-4w87A:
undetectable		 2fl5E-4w87A:
18.44
2fl5F-4w87A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		5 / 12 LEU A 301
ASN A 262
LEU A 260
ALA A 263
LEU A 215
 None
 1.42A 2oaxD-4w87A:
undetectable		 2oaxD-4w87A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 GLN A 221
THR A 193
TRP A 200
 None
 1.10A 2rctA-4w87A:
undetectable		 2rctA-4w87A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		6 / 12 ASN A 239
GLU A 240
HIS A 314
TYR A 316
GLU A 362
TRP A 395
 None
BGC  A 502 ( 3.2A)
None
None
None
None
 0.85A 2v3dA-4w87A:
18.1		 2v3dA-4w87A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X08_A_ASCA1253_0
(CYTOCHROME C
PEROXIDASE,
MITOCHONDRIAL)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		5 / 9 ALA A 310
ILE A 286
PRO A 304
ASN A 308
ARG A 273
 None
 1.14A 2x08A-4w87A:
undetectable		 2x08A-4w87A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		4 / 6 THR A 133
ILE A 151
LEU A 113
THR A 112
 None
 0.97A 3deuB-4w87A:
undetectable		 3deuB-4w87A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		5 / 12 GLY A 334
ASN A 333
ASP A 380
GLY A 383
THR A 341
 None
 1.20A 3eeyJ-4w87A:
undetectable		 3eeyJ-4w87A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		5 / 12 LEU A 222
GLY A 237
LEU A 100
VAL A 359
ILE A 103
 None
 1.05A 3frqB-4w87A:
undetectable		 3frqB-4w87A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 GLU A 236
HIS A 291
THR A 361
 None
 0.60A 3hkuA-4w87A:
undetectable		 3hkuA-4w87A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		4 / 6 TRP A 200
LEU A 159
GLU A 214
THR A 193
 None
 1.34A 3ropA-4w87A:
undetectable		 3ropA-4w87A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		5 / 12 GLU A 125
ARG A 174
ILE A 151
ALA A 182
ILE A 149
 None
 1.24A 4uroC-4w87A:
undetectable		 4uroC-4w87A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 THR A 361
GLU A 236
HIS A 194
 None
 0.87A 5xioA-4w87A:
undetectable		 5xioA-4w87A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 GLU A 240
TRP A 250
HIS A 195
 BGC  A 502 ( 3.2A)
BGC  A 502 ( 3.8A)
None
 1.06A 5xipA-4w87A:
undetectable		 5xipA-4w87A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 THR A 361
GLU A 236
HIS A 194
 None
 0.80A 5xiqB-4w87A:
undetectable		 5xiqB-4w87A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 THR A 361
GLU A 236
HIS A 194
 None
 0.82A 5xiqD-4w87A:
undetectable		 5xiqD-4w87A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		3 / 3 MET A 187
ASP A 139
ARG A 174
 None
 1.19A 5z6kA-4w87A:
undetectable		 5z6kA-4w87A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		4 / 6 MET A 243
GLY A 253
ALA A 256
LEU A 260
 None
 1.07A 6fosA-4w87A:
undetectable		 6fosA-4w87A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE
(uncultured
bacterium) 		4 / 7 SER A 101
ARG A  93
ILE A 309
ALA A 310
 None
 0.92A 6ma7A-4w87A:
undetectable		 6ma7A-4w87A:
11.31