SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4w8b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 4 SER A 247
LEU A 308
TYR A 253
GLY A 245
 None
 1.42A 1liiA-4w8bA:
1.5		 1liiA-4w8bA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 7 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.21A 1v55C-4w8bA:
undetectable
1v55N-4w8bA:
undetectable
1v55P-4w8bA:
undetectable		 1v55C-4w8bA:
22.14
1v55N-4w8bA:
19.46
1v55P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 6 ASN A 500
ASN A 447
ILE A 439
GLN A 443
 XYS  A 618 (-3.1A)
XYS  A 618 (-3.4A)
None
XYS  A 618 ( 4.2A)
 1.20A 2hkkA-4w8bA:
undetectable		 2hkkA-4w8bA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		6 / 12 ASN A 292
GLU A 293
HIS A 368
TYR A 370
GLU A 431
TRP A 471
 GLC  A 601 (-3.1A)
GLC  A 601 (-3.0A)
None
GLC  A 601 (-4.5A)
GLC  A 601 (-2.8A)
GLC  A 601 ( 4.0A)
 0.71A 2v3dA-4w8bA:
17.8		 2v3dA-4w8bA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 11 ASN A 292
GLU A 293
TYR A 370
GLU A 431
TRP A 471
 GLC  A 601 (-3.1A)
GLC  A 601 (-3.0A)
GLC  A 601 (-4.5A)
GLC  A 601 (-2.8A)
GLC  A 601 ( 4.0A)
 0.80A 2v3dB-4w8bA:
15.1		 2v3dB-4w8bA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.12A 2y69C-4w8bA:
undetectable
2y69N-4w8bA:
undetectable
2y69P-4w8bA:
undetectable		 2y69C-4w8bA:
22.14
2y69N-4w8bA:
19.46
2y69P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.14A 3ablA-4w8bA:
undetectable
3ablC-4w8bA:
undetectable
3ablP-4w8bA:
undetectable		 3ablA-4w8bA:
19.46
3ablC-4w8bA:
22.14
3ablP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.14A 3ablC-4w8bA:
undetectable
3ablN-4w8bA:
undetectable
3ablP-4w8bA:
undetectable		 3ablC-4w8bA:
22.14
3ablN-4w8bA:
19.46
3ablP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.13A 3abmA-4w8bA:
undetectable
3abmC-4w8bA:
undetectable
3abmP-4w8bA:
undetectable		 3abmA-4w8bA:
19.46
3abmC-4w8bA:
22.14
3abmP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.13A 3asnC-4w8bA:
undetectable
3asnN-4w8bA:
undetectable
3asnP-4w8bA:
undetectable		 3asnC-4w8bA:
22.14
3asnN-4w8bA:
19.46
3asnP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.17A 3asoA-4w8bA:
undetectable
3asoC-4w8bA:
undetectable
3asoP-4w8bA:
undetectable		 3asoA-4w8bA:
19.46
3asoC-4w8bA:
22.14
3asoP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.16A 3asoC-4w8bA:
undetectable
3asoN-4w8bA:
undetectable
3asoP-4w8bA:
undetectable		 3asoC-4w8bA:
22.14
3asoN-4w8bA:
19.46
3asoP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 12 ALA A 381
ALA A 386
GLN A 374
ASN A 400
PHE A 375
 None
 1.08A 3e00A-4w8bA:
undetectable		 3e00A-4w8bA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 7 VAL A 256
ILE A 265
TYR A 315
GLY A 245
 None
 1.03A 3gssA-4w8bA:
undetectable		 3gssA-4w8bA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		3 / 3 TYR A 452
TYR A 460
GLU A 405
 None
 0.83A 3pfgA-4w8bA:
undetectable		 3pfgA-4w8bA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.13A 3wg7A-4w8bA:
undetectable
3wg7C-4w8bA:
undetectable
3wg7P-4w8bA:
undetectable		 3wg7A-4w8bA:
19.46
3wg7C-4w8bA:
22.14
3wg7P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.14A 3wg7C-4w8bA:
undetectable
3wg7N-4w8bA:
undetectable
3wg7P-4w8bA:
undetectable		 3wg7C-4w8bA:
22.14
3wg7N-4w8bA:
19.46
3wg7P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.18A 3x2qC-4w8bA:
undetectable
3x2qN-4w8bA:
undetectable
3x2qP-4w8bA:
undetectable		 3x2qC-4w8bA:
22.14
3x2qN-4w8bA:
19.46
3x2qP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 12 ILE A 208
LEU A 286
VAL A 230
LEU A 232
ILE A 275
 None
 0.97A 4km2B-4w8bA:
undetectable		 4km2B-4w8bA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 12 VAL A 505
VAL A 497
PHE A 189
ALA A 468
VAL A 450
 None
BGC  A 616 (-4.9A)
None
None
None
 1.33A 4nc3A-4w8bA:
undetectable		 4nc3A-4w8bA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 9 VAL A 220
VAL A 216
ILE A 275
PHE A 288
LEU A 286
 None
 1.30A 5e4dA-4w8bA:
undetectable		 5e4dA-4w8bA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 12 GLU A 431
ARG A 193
TRP A 152
THR A 176
LEU A 154
 GLC  A 601 (-2.8A)
None
None
None
None
 1.49A 5fhzD-4w8bA:
undetectable		 5fhzD-4w8bA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		3 / 3 TRP A 171
ILE A 200
SER A 197
 BGC  A 603 ( 4.3A)
None
None
 1.04A 5gqbA-4w8bA:
11.6		 5gqbA-4w8bA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 10 ILE A 428
ILE A 467
VAL A 336
TYR A 229
ILE A 144
 None
 1.31A 5mvnD-4w8bA:
undetectable		 5mvnD-4w8bA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 10 ILE A 428
ILE A 467
VAL A 336
TYR A 229
ILE A 144
 None
 1.35A 5mzrA-4w8bA:
undetectable		 5mzrA-4w8bA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 10 ILE A 428
ILE A 467
VAL A 336
TYR A 229
ILE A 144
 None
 1.34A 5mzrC-4w8bA:
undetectable		 5mzrC-4w8bA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		5 / 9 ILE A 428
ILE A 467
VAL A 336
TYR A 229
ILE A 144
 None
 1.36A 5mzrD-4w8bA:
undetectable		 5mzrD-4w8bA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 7 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.22A 5w97C-4w8bA:
undetectable
5w97a-4w8bA:
undetectable
5w97c-4w8bA:
undetectable		 5w97C-4w8bA:
22.14
5w97a-4w8bA:
19.46
5w97c-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 7 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.16A 5wauC-4w8bA:
undetectable
5waua-4w8bA:
undetectable
5wauc-4w8bA:
undetectable		 5wauC-4w8bA:
22.14
5waua-4w8bA:
19.46
5wauc-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.14A 5x19A-4w8bA:
undetectable
5x19C-4w8bA:
undetectable
5x19P-4w8bA:
undetectable		 5x19A-4w8bA:
19.46
5x19C-4w8bA:
22.14
5x19P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 7 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.15A 5x1fA-4w8bA:
undetectable
5x1fC-4w8bA:
undetectable
5x1fP-4w8bA:
undetectable		 5x1fA-4w8bA:
19.46
5x1fC-4w8bA:
22.14
5x1fP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 7 VAL A 184
VAL A 505
PRO A 150
GLY A 151
 None
 0.99A 5x80C-4w8bA:
undetectable
5x80D-4w8bA:
undetectable		 5x80C-4w8bA:
16.05
5x80D-4w8bA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.15A 5xdqA-4w8bA:
undetectable
5xdqC-4w8bA:
undetectable
5xdqP-4w8bA:
undetectable		 5xdqA-4w8bA:
19.46
5xdqC-4w8bA:
22.14
5xdqP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.16A 5xdqC-4w8bA:
undetectable
5xdqN-4w8bA:
undetectable
5xdqP-4w8bA:
undetectable		 5xdqC-4w8bA:
22.14
5xdqN-4w8bA:
19.46
5xdqP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.20A 5xdxC-4w8bA:
undetectable
5xdxN-4w8bA:
undetectable
5xdxP-4w8bA:
undetectable		 5xdxC-4w8bA:
22.14
5xdxN-4w8bA:
19.46
5xdxP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.14A 5z84A-4w8bA:
undetectable
5z84C-4w8bA:
undetectable
5z84P-4w8bA:
undetectable		 5z84A-4w8bA:
19.46
5z84C-4w8bA:
22.14
5z84P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 7 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.17A 5z84C-4w8bA:
undetectable
5z84N-4w8bA:
undetectable
5z84P-4w8bA:
undetectable		 5z84C-4w8bA:
22.14
5z84N-4w8bA:
19.46
5z84P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.15A 5z85A-4w8bA:
undetectable
5z85C-4w8bA:
undetectable
5z85P-4w8bA:
undetectable		 5z85A-4w8bA:
19.46
5z85C-4w8bA:
22.14
5z85P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 7 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.16A 5z85C-4w8bA:
undetectable
5z85N-4w8bA:
undetectable
5z85P-4w8bA:
undetectable		 5z85C-4w8bA:
22.14
5z85N-4w8bA:
19.46
5z85P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.15A 5z86A-4w8bA:
undetectable
5z86C-4w8bA:
undetectable
5z86P-4w8bA:
undetectable		 5z86A-4w8bA:
19.46
5z86C-4w8bA:
22.14
5z86P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.17A 5z86C-4w8bA:
undetectable
5z86N-4w8bA:
undetectable
5z86P-4w8bA:
undetectable		 5z86C-4w8bA:
22.14
5z86N-4w8bA:
19.46
5z86P-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.14A 5zcoA-4w8bA:
undetectable
5zcoC-4w8bA:
undetectable
5zcoP-4w8bA:
undetectable		 5zcoA-4w8bA:
19.46
5zcoC-4w8bA:
22.14
5zcoP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.14A 5zcoC-4w8bA:
undetectable
5zcoN-4w8bA:
undetectable
5zcoP-4w8bA:
undetectable		 5zcoC-4w8bA:
22.14
5zcoN-4w8bA:
19.46
5zcoP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.14A 5zcpA-4w8bA:
undetectable
5zcpC-4w8bA:
undetectable
5zcpP-4w8bA:
undetectable		 5zcpA-4w8bA:
19.46
5zcpC-4w8bA:
22.14
5zcpP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU A 479
ASP A 475
THR A 473
HIS A 368
 XYS  A 618 ( 4.0A)
XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
 1.14A 5zcpC-4w8bA:
undetectable
5zcpN-4w8bA:
undetectable
5zcpP-4w8bA:
undetectable		 5zcpC-4w8bA:
22.14
5zcpN-4w8bA:
19.46
5zcpP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		4 / 8 ASP A 475
THR A 473
HIS A 368
LEU A 479
 XYS  A 606 ( 4.1A)
BGC  A 602 ( 4.3A)
None
XYS  A 618 ( 4.0A)
 1.14A 5zcqA-4w8bA:
undetectable
5zcqC-4w8bA:
undetectable
5zcqP-4w8bA:
undetectable		 5zcqA-4w8bA:
19.46
5zcqC-4w8bA:
22.14
5zcqP-4w8bA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4w8b EXO-XYLOGLUCANASE
(uncultured
bacterium) 		3 / 3 THR A 174
GLU A 159
ASN A 474
 None
 0.88A 6nj9K-4w8bA:
undetectable		 6nj9K-4w8bA:
21.68