SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4w8h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_C_NCAC439_0 (ADP-RIBOSYL CYCLASE)	4w8h	TOLL-RECEPTOR-RELATE D 2 (Hydra vulgaris)	3 / 3	TRP A 201 PHE A 210 TRP A 211	None	1.23A	1r15C-4w8hA: 3.3	1r15C-4w8hA: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_F_NCAF469_0 (ADP-RIBOSYL CYCLASE)	4w8h	TOLL-RECEPTOR-RELATE D 2 (Hydra vulgaris)	3 / 3	TRP A 201 PHE A 210 TRP A 211	None	1.22A	1r15F-4w8hA: 3.5	1r15F-4w8hA: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_G_NCAG479_0 (ADP-RIBOSYL CYCLASE)	4w8h	TOLL-RECEPTOR-RELATE D 2 (Hydra vulgaris)	3 / 3	TRP A 201 PHE A 210 TRP A 211	None	1.23A	1r15G-4w8hA: 3.5	1r15G-4w8hA: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R15_H_NCAH489_0 (ADP-RIBOSYL CYCLASE)	4w8h	TOLL-RECEPTOR-RELATE D 2 (Hydra vulgaris)	3 / 3	TRP A 201 PHE A 210 TRP A 211	None	1.23A	1r15H-4w8hA: 3.4	1r15H-4w8hA: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_F_TFPF211_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	4w8h	TOLL-RECEPTOR-RELATE D 2 (Hydra vulgaris)	4 / 7	LEU A 214 PHE A 210 LEU A 115 SER A 158	None	1.01A	1wrlE-4w8hA: undetectable 1wrlF-4w8hA: undetectable	1wrlE-4w8hA: 21.54 1wrlF-4w8hA: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RLF_D_RIMD499_1 (MATRIX PROTEIN 2)	4w8h	TOLL-RECEPTOR-RELATE D 2 (Hydra vulgaris)	4 / 6	ILE A 154 ARG A 152 LEU A 214 ASP A 217	None	1.01A	2rlfA-4w8hA: undetectable 2rlfD-4w8hA: undetectable	2rlfA-4w8hA: 14.63 2rlfD-4w8hA: 14.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1R15_C_NCAC439_0","ADP-RIBOSYL CYCLASE","4w8h","TOLL-RECEPTOR-RELATED 2","Hydra vulgaris",3,"TRP A 201;PHE A 210;TRP A 211","None","1.23A","1r15C-4w8hA:3.3","1r15C-4w8hA:14.73"],["1R15_F_NCAF469_0","ADP-RIBOSYL CYCLASE","4w8h","TOLL-RECEPTOR-RELATED 2","Hydra vulgaris",3,"TRP A 201;PHE A 210;TRP A 211","None","1.22A","1r15F-4w8hA:3.5","1r15F-4w8hA:14.73"],["1R15_G_NCAG479_0","ADP-RIBOSYL CYCLASE","4w8h","TOLL-RECEPTOR-RELATED 2","Hydra vulgaris",3,"TRP A 201;PHE A 210;TRP A 211","None","1.23A","1r15G-4w8hA:3.5","1r15G-4w8hA:14.73"],["1R15_H_NCAH489_0","ADP-RIBOSYL CYCLASE","4w8h","TOLL-RECEPTOR-RELATED 2","Hydra vulgaris",3,"TRP A 201;PHE A 210;TRP A 211","None","1.23A","1r15H-4w8hA:3.4","1r15H-4w8hA:14.73"],["1WRL_F_TFPF211_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES;TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","4w8h","TOLL-RECEPTOR-RELATED 2","Hydra vulgaris",4,"LEU A 214;PHE A 210;LEU A 115;SER A 158","None","1.01A","1wrlE-4w8hA:undetectable;1wrlF-4w8hA:undetectable","1wrlE-4w8hA:21.54;1wrlF-4w8hA:21.54"],["2RLF_D_RIMD499_1","MATRIX PROTEIN 2;MATRIX PROTEIN 2","4w8h","TOLL-RECEPTOR-RELATED 2","Hydra vulgaris",4,"ILE A 154;ARG A 152;LEU A 214;ASP A 217","None","1.01A","2rlfA-4w8hA:undetectable;2rlfD-4w8hA:undetectable","2rlfA-4w8hA:14.63;2rlfD-4w8hA:14.63"]]