SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wan'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 4wan BRANCHPOINT-BRIDGING
PROTEIN
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 166
LEU A 168
LEU A 169
ILE A 189
 U  B   6 ( 3.7A)
None
A  B   7 ( 3.8A)
A  B   8 ( 4.2A)
 0.85A 3nbqB-4wanA:
undetectable		 3nbqB-4wanA:
16.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 4wan BRANCHPOINT-BRIDGING
PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 157
ARG A 192
PRO A 214
 SO4  A 301 ( 4.3A)
SO4  A 301 (-3.3A)
SO4  A 301 ( 4.5A)
 0.17A 4wanC-4wanA:
23.0		 4wanC-4wanA:
100.00