SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 4wau CENTROMERE PROTEIN M
(Homo
sapiens) 		3 / 3 LEU A 100
LEU A  28
MET A  35
 None
 0.77A 1ya3B-4wauA:
undetectable		 1ya3B-4wauA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 4wau CENTROMERE PROTEIN M
(Homo
sapiens) 		5 / 11 VAL A  69
GLY A  22
LEU A 133
ARG A 139
SER A  34
 None
 1.19A 2bxgA-4wauA:
undetectable		 2bxgA-4wauA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4wau CENTROMERE PROTEIN M
(Homo
sapiens) 		4 / 8 SER A 126
GLU A  82
GLY A  22
LYS A  50
 None
 0.89A 4fgzA-4wauA:
undetectable
4fgzB-4wauA:
undetectable		 4fgzA-4wauA:
19.63
4fgzB-4wauA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 4wau CENTROMERE PROTEIN M
(Homo
sapiens) 		5 / 12 LEU A 133
ILE A  18
LEU A  48
ALA A 143
LEU A  36
 None
 0.98A 5og9B-4wauA:
undetectable		 5og9B-4wauA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 4wau CENTROMERE PROTEIN M
(Homo
sapiens) 		4 / 4 LYS A  50
LEU A  28
ALA A  49
LEU A  20
 None
 1.48A 6gnrA-4wauA:
undetectable		 6gnrA-4wauA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 4wau CENTROMERE PROTEIN M
(Homo
sapiens) 		4 / 4 LYS A  50
LEU A  28
ALA A  49
LEU A  20
 None
 1.46A 6gnrB-4wauA:
undetectable		 6gnrB-4wauA:
24.86