SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wbp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 4wbp CAPRIN-1
(Homo
sapiens) 		5 / 12 ARG A 165
SER A 179
LEU A 233
LEU A 156
ASP A 187
 None
 1.40A 1e7wA-4wbpA:
undetectable		 1e7wA-4wbpA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wbp CAPRIN-1
(Homo
sapiens) 		3 / 3 SER A 179
GLU A 180
GLU A 181
 None
 0.54A 1eqbD-4wbpA:
undetectable		 1eqbD-4wbpA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wbp CAPRIN-1
(Homo
sapiens) 		3 / 3 SER A 179
GLU A 180
GLU A 181
 None
 0.54A 1eqbB-4wbpA:
undetectable		 1eqbB-4wbpA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 4wbp CAPRIN-1
(Homo
sapiens) 		4 / 4 THR A 148
LEU A 152
VAL A 155
LEU A 159
 None
 0.81A 1fbmB-4wbpA:
undetectable		 1fbmB-4wbpA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 4wbp CAPRIN-1
(Homo
sapiens) 		4 / 5 GLU A 180
LEU A 186
LEU A 183
LEU A 185
 None
 1.04A 1np1A-4wbpA:
undetectable		 1np1A-4wbpA:
20.00