SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wct'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 10 THR A 239
PRO A 238
ARG A 410
THR A 347
GLY A 368
 None
 1.32A 1h4oA-4wctA:
undetectable
1h4oB-4wctA:
undetectable		 1h4oA-4wctA:
15.73
1h4oB-4wctA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 9 THR A 239
PRO A 238
ARG A 410
THR A 347
GLY A 368
 None
 1.18A 1h4oC-4wctA:
undetectable
1h4oD-4wctA:
undetectable		 1h4oC-4wctA:
15.73
1h4oD-4wctA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 9 THR A 239
PRO A 238
ARG A 410
THR A 347
GLY A 368
 None
 1.17A 1h4oE-4wctA:
undetectable
1h4oF-4wctA:
undetectable		 1h4oE-4wctA:
15.73
1h4oF-4wctA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 ARG A  31
ILE A 384
ALA A 385
LEU A  28
ALA A  29
 None
 1.44A 1jb0B-4wctA:
undetectable		 1jb0B-4wctA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 ILE A 384
HIS A 357
LEU A 353
TYR A 197
ASP A 201
 None
 1.36A 1mrlA-4wctA:
undetectable
1mrlB-4wctA:
undetectable		 1mrlA-4wctA:
17.07
1mrlB-4wctA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 VAL A 192
VAL A 367
LEU A 229
LEU A 220
LEU A 236
 FAD  A 500 (-3.8A)
None
FAD  A 500 ( 4.9A)
None
None
 1.36A 1mx1E-4wctA:
undetectable		 1mx1E-4wctA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 ILE A 380
GLY A 368
PHE A 383
ASN A 372
ALA A 351
 None
 1.13A 1nv8A-4wctA:
undetectable		 1nv8A-4wctA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 ILE A 380
GLY A 368
PHE A 383
ASN A 372
ALA A 351
 None
 1.15A 1sg9C-4wctA:
2.1		 1sg9C-4wctA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		3 / 3 SER A 370
GLY A 369
ARG A 403
 None
FAD  A 500 (-3.5A)
None
 0.62A 1t9wA-4wctA:
undetectable		 1t9wA-4wctA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 THR A 347
GLY A 368
GLY A 371
VAL A 365
ILE A 384
 None
None
FAD  A 500 (-3.7A)
None
None
 1.07A 2b25B-4wctA:
undetectable		 2b25B-4wctA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 7 TRP A  86
GLY A 382
GLY A 373
PHE A  92
 None
None
FAD  A 500 (-3.1A)
None
 0.88A 2qwxA-4wctA:
undetectable
2qwxB-4wctA:
undetectable		 2qwxA-4wctA:
19.95
2qwxB-4wctA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 10 THR A 239
PRO A 238
ARG A 410
THR A 347
GLY A 368
 None
 1.16A 2vl2A-4wctA:
undetectable
2vl2C-4wctA:
undetectable		 2vl2A-4wctA:
16.67
2vl2C-4wctA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 5 GLN A  93
THR A  88
HIS A  27
LEU A  26
 None
 1.20A 2zj0A-4wctA:
undetectable		 2zj0A-4wctA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		3 / 3 THR A 327
PRO A 329
THR A 145
 None
 0.86A 316dC-4wctA:
undetectable		 316dC-4wctA:
2.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 5 GLN A  93
THR A  88
HIS A  27
LEU A  26
 None
 1.28A 3ce6A-4wctA:
undetectable		 3ce6A-4wctA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 5 GLN A  93
THR A  88
HIS A  27
LEU A  26
 None
 1.24A 3ce6C-4wctA:
undetectable		 3ce6C-4wctA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 5 GLN A  93
THR A  88
HIS A  27
LEU A  26
 None
 1.25A 3ce6D-4wctA:
2.0		 3ce6D-4wctA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 PHE A 419
PRO A 329
GLY A 105
SER A 104
LEU A 110
 None
 1.20A 3e23A-4wctA:
2.5		 3e23A-4wctA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 9 ILE A  12
ILE A 219
ALA A 387
LEU A 388
ALA A 215
 None
 1.01A 3ozvB-4wctA:
undetectable		 3ozvB-4wctA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 ARG A  31
ILE A 384
ALA A 385
LEU A  28
ALA A  29
 None
 1.44A 3pcqB-4wctA:
undetectable		 3pcqB-4wctA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 9 ARG A  31
ILE A 384
ALA A 385
LEU A  28
ALA A  29
 None
 1.49A 4fe1B-4wctA:
undetectable		 4fe1B-4wctA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 VAL A  14
ALA A 222
SER A  23
THR A 185
VAL A  38
 None
FAD  A 500 (-3.7A)
None
None
None
 1.25A 4kyaA-4wctA:
undetectable		 4kyaA-4wctA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 VAL A  14
ALA A 222
SER A  23
THR A 185
VAL A  38
 None
FAD  A 500 (-3.7A)
None
None
None
 1.23A 4kyaE-4wctA:
undetectable		 4kyaE-4wctA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 VAL A  14
ALA A 222
SER A  23
THR A 185
VAL A  38
 None
FAD  A 500 (-3.7A)
None
None
None
 1.23A 4kyaG-4wctA:
undetectable		 4kyaG-4wctA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 10 ARG A  31
ILE A 384
ALA A 385
LEU A  28
ALA A  29
 None
 1.49A 4xk8B-4wctA:
undetectable		 4xk8B-4wctA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 MET A 248
ILE A 246
TYR A 256
VAL A 253
THR A 138
 None
 1.23A 5igiA-4wctA:
undetectable		 5igiA-4wctA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 10 ALA A  82
THR A  79
ALA A 374
GLY A 373
THR A  19
 None
None
FAD  A 500 (-3.5A)
FAD  A 500 (-3.1A)
FAD  A 500 (-3.2A)
 1.14A 5lf3H-4wctA:
undetectable
5lf3I-4wctA:
undetectable		 5lf3H-4wctA:
21.49
5lf3I-4wctA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 10 ALA A  82
THR A  79
ALA A 374
GLY A 373
THR A  19
 None
None
FAD  A 500 (-3.5A)
FAD  A 500 (-3.1A)
FAD  A 500 (-3.2A)
 1.13A 5lf3V-4wctA:
undetectable
5lf3W-4wctA:
undetectable		 5lf3V-4wctA:
21.49
5lf3W-4wctA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 ALA A  82
THR A  79
ALA A 374
GLY A 373
LEU A 392
 None
None
FAD  A 500 (-3.5A)
FAD  A 500 (-3.1A)
None
 0.95A 5lf7H-4wctA:
undetectable
5lf7I-4wctA:
undetectable		 5lf7H-4wctA:
21.49
5lf7I-4wctA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 ALA A  82
THR A  79
ALA A 374
GLY A 373
THR A  19
 None
None
FAD  A 500 (-3.5A)
FAD  A 500 (-3.1A)
FAD  A 500 (-3.2A)
 1.12A 5lf7H-4wctA:
undetectable
5lf7I-4wctA:
undetectable		 5lf7H-4wctA:
21.49
5lf7I-4wctA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 ALA A  82
THR A  79
ALA A 374
GLY A 373
LEU A 392
 None
None
FAD  A 500 (-3.5A)
FAD  A 500 (-3.1A)
None
 0.94A 5lf7V-4wctA:
undetectable
5lf7W-4wctA:
undetectable		 5lf7V-4wctA:
21.49
5lf7W-4wctA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 11 ALA A  82
THR A  79
ALA A 374
GLY A 373
THR A  19
 None
None
FAD  A 500 (-3.5A)
FAD  A 500 (-3.1A)
FAD  A 500 (-3.2A)
 1.10A 5lf7V-4wctA:
undetectable
5lf7W-4wctA:
undetectable		 5lf7V-4wctA:
21.49
5lf7W-4wctA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 9 LEU A 220
ILE A  15
GLY A  16
GLY A  21
LEU A 363
 None
FAD  A 500 (-4.7A)
FAD  A 500 (-3.5A)
None
None
 0.99A 5o96A-4wctA:
undetectable
5o96B-4wctA:
undetectable		 5o96A-4wctA:
19.96
5o96B-4wctA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 220
ILE A  15
GLY A  16
GLY A  21
LEU A 363
 None
FAD  A 500 (-4.7A)
FAD  A 500 (-3.5A)
None
None
 0.95A 5twjA-4wctA:
undetectable		 5twjA-4wctA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 10 LEU A 220
ILE A  15
GLY A  16
GLY A  21
LEU A 363
 None
FAD  A 500 (-4.7A)
FAD  A 500 (-3.5A)
None
None
 1.00A 5twjB-4wctA:
undetectable		 5twjB-4wctA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 7 THR A 239
ILE A 341
THR A 242
PHE A 428
 None
 1.01A 5zsfA-4wctA:
undetectable
5zsfB-4wctA:
undetectable		 5zsfA-4wctA:
9.98
5zsfB-4wctA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_2
(-)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 4 GLN A  93
THR A  88
HIS A  27
LEU A  26
 None
 1.45A 6f3nB-4wctA:
2.4		 6f3nB-4wctA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		3 / 3 THR A 379
ALA A  85
LYS A  87
 None
 0.47A 6fgcA-4wctA:
undetectable		 6fgcA-4wctA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		3 / 3 THR A 379
ALA A  85
LYS A  87
 None
 0.47A 6fgdA-4wctA:
2.1		 6fgdA-4wctA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		4 / 6 MET A 377
GLY A  21
ALA A 176
LEU A  26
 None
 1.02A 6fosA-4wctA:
undetectable		 6fosA-4wctA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE
(Aspergillus
fumigatus) 		5 / 9 ARG A  31
ILE A 384
ALA A 385
LEU A  28
ALA A  29
 None
 1.43A 6hqbB-4wctA:
undetectable		 6hqbB-4wctA:
11.62