SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wem'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_D_ADND500_2 (ADENOSYLHOMOCYSTEINA SE)	4wem	ANTI-F4+ETEC BACTERIA VHH VARIABLE REGION (Lama glama)	4 / 5	LEU B 820 GLN B 916 THR B 915 LEU B 885	None	1.19A	3ce6D-4wemB: undetectable	3ce6D-4wemB: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V8V_B_SAMB802_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L)	4wem	ANTI-F4+ETEC BACTERIA VHH VARIABLE REGION (Lama glama)	5 / 12	ARG B 819 SER B 821 SER B 825 ASP B 829 ASP B 872	None	1.36A	3v8vB-4wemB: undetectable	3v8vB-4wemB: 10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_A_SAMA602_0 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	4wem	ANTI-F4+ETEC BACTERIA VHH VARIABLE REGION (Lama glama)	5 / 12	GLY B 901 SER B 898 ILE B 851 GLY B 855 ASN B 858	None	1.22A	4obwA-4wemB: undetectable	4obwA-4wemB: 16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_C_SAMC601_0 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	4wem	ANTI-F4+ETEC BACTERIA VHH VARIABLE REGION (Lama glama)	5 / 12	GLY B 901 SER B 898 ILE B 851 GLY B 855 ASN B 858	None	1.24A	4obwC-4wemB: undetectable	4obwC-4wemB: 16.34

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CE6_D_ADND500_2","ADENOSYLHOMOCYSTEINASE","4wem","ANTI-F4+ETEC BACTERIA VHH VARIABLE REGION","Lama glama",4,"LEU B 820;GLN B 916;THR B 915;LEU B 885","None","1.19A","3ce6D-4wemB:undetectable","3ce6D-4wemB:13.33"],["3V8V_B_SAMB802_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE L","4wem","ANTI-F4+ETEC BACTERIA VHH VARIABLE REGION","Lama glama",5,"ARG B 819;SER B 821;SER B 825;ASP B 829;ASP B 872","None","1.36A","3v8vB-4wemB:undetectable","3v8vB-4wemB:10.95"],["4OBW_A_SAMA602_0","2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL","4wem","ANTI-F4+ETEC BACTERIA VHH VARIABLE REGION","Lama glama",5,"GLY B 901;SER B 898;ILE B 851;GLY B 855;ASN B 858","None","1.22A","4obwA-4wemB:undetectable","4obwA-4wemB:16.34"],["4OBW_C_SAMC601_0","2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL","4wem","ANTI-F4+ETEC BACTERIA VHH VARIABLE REGION","Lama glama",5,"GLY B 901;SER B 898;ILE B 851;GLY B 855;ASN B 858","None","1.24A","4obwC-4wemB:undetectable","4obwC-4wemB:16.34"]]