SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wfq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_A_ADNA1501_1
(CLASS B ACID
PHOSPHATASE)		 4wfq SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 10 ASP A 284
PHE A 287
LEU A 308
THR A 280
TYR A 282
 None
 1.23A 1rmtA-4wfqA:
3.3		 1rmtA-4wfqA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 4wfq SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 8 ASP A 284
PHE A 287
LEU A 308
THR A 280
TYR A 282
 None
 1.27A 1rmtD-4wfqA:
2.0		 1rmtD-4wfqA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4wfq SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 300
LEU A 266
SER A 267
LEU A 292
 None
 1.15A 1ya3A-4wfqA:
undetectable		 1ya3A-4wfqA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B8J_B_ADNB331_1
(CLASS B ACID
PHOSPHATASE)		 4wfq SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 10 ASP A 284
PHE A 287
LEU A 308
THR A 280
TYR A 282
 None
 1.24A 2b8jB-4wfqA:
2.5		 2b8jB-4wfqA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4wfq SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 232
PRO A 208
ILE A 272
VAL A 270
CYH A 273
 None
 1.32A 3p6gA-4wfqA:
undetectable		 3p6gA-4wfqA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 4wfq SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 276
LEU A 264
LEU A 297
ALA A 153
PHE A 156
 None
 1.43A 4rtbA-4wfqA:
undetectable		 4rtbA-4wfqA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 4wfq SUPPRESSOR OF
STEM-LOOP PROTEIN 1
(Saccharomyces
cerevisiae) 		4 / 7 THR A 280
LEU A 254
ILE A 247
THR A 250
 None
 0.96A 5zsfA-4wfqA:
undetectable
5zsfB-4wfqA:
undetectable		 5zsfA-4wfqA:
16.32
5zsfB-4wfqA:
16.32