SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wfw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KT3_A_RTLA184_0 (PLASMA RETINOL-BINDING PROTEIN)	4wfw	GENERAL SECRETION PATHWAY PROTEIN B (Dickeya dadantii)	4 / 7	LEU A 187 LEU A 184 TYR A 129 LEU A 148	None	1.06A	1kt3A-4wfwA: undetectable	1kt3A-4wfwA: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IB0_A_DIFA701_1 (LACTOTRANSFERRIN)	4wfw	GENERAL SECRETION PATHWAY PROTEIN B (Dickeya dadantii)	4 / 4	PRO A 128 TYR A 160 GLY A 118 THR A 117	None	1.50A	3ib0A-4wfwA: undetectable	3ib0A-4wfwA: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y4D_A_CFFA411_1 (ENDOTHIAPEPSIN)	4wfw	GENERAL SECRETION PATHWAY PROTEIN B (Dickeya dadantii)	4 / 6	LEU A 127 PHE A 177 ILE A 183 PHE A 182	None	1.09A	4y4dA-4wfwA: undetectable	4y4dA-4wfwA: 15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_B_Z80B401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4wfw	GENERAL SECRETION PATHWAY PROTEIN B (Dickeya dadantii)	5 / 9	PHE A 182 VAL A 146 ASN A 149 ASP A 189 TRP A 190	None	1.48A	5lg3B-4wfwA: undetectable	5lg3B-4wfwA: 14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_C_Z80C401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4wfw	GENERAL SECRETION PATHWAY PROTEIN B (Dickeya dadantii)	5 / 9	PHE A 182 VAL A 146 ASN A 149 ASP A 189 TRP A 190	None	1.46A	5lg3C-4wfwA: undetectable	5lg3C-4wfwA: 14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_D_Z80D401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4wfw	GENERAL SECRETION PATHWAY PROTEIN B (Dickeya dadantii)	5 / 9	PHE A 182 VAL A 146 ASN A 149 ASP A 189 TRP A 190	None	1.47A	5lg3D-4wfwA: undetectable	5lg3D-4wfwA: 14.01

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1KT3_A_RTLA184_0","PLASMA RETINOL-BINDING PROTEIN","4wfw","GENERAL SECRETION PATHWAY PROTEIN B","Dickeya dadantii",4,"LEU A 187;LEU A 184;TYR A 129;LEU A 148","None","1.06A","1kt3A-4wfwA:undetectable","1kt3A-4wfwA:20.73"],["3IB0_A_DIFA701_1","LACTOTRANSFERRIN","4wfw","GENERAL SECRETION PATHWAY PROTEIN B","Dickeya dadantii",4,"PRO A 128;TYR A 160;GLY A 118;THR A 117","None","1.50A","3ib0A-4wfwA:undetectable","3ib0A-4wfwA:13.33"],["4Y4D_A_CFFA411_1","ENDOTHIAPEPSIN","4wfw","GENERAL SECRETION PATHWAY PROTEIN B","Dickeya dadantii",4,"LEU A 127;PHE A 177;ILE A 183;PHE A 182","None","1.09A","4y4dA-4wfwA:undetectable","4y4dA-4wfwA:15.57"],["5LG3_B_Z80B401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","4wfw","GENERAL SECRETION PATHWAY PROTEIN B","Dickeya dadantii",5,"PHE A 182;VAL A 146;ASN A 149;ASP A 189;TRP A 190","None","1.48A","5lg3B-4wfwA:undetectable","5lg3B-4wfwA:14.01"],["5LG3_C_Z80C401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","4wfw","GENERAL SECRETION PATHWAY PROTEIN B","Dickeya dadantii",5,"PHE A 182;VAL A 146;ASN A 149;ASP A 189;TRP A 190","None","1.46A","5lg3C-4wfwA:undetectable","5lg3C-4wfwA:14.01"],["5LG3_D_Z80D401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","4wfw","GENERAL SECRETION PATHWAY PROTEIN B","Dickeya dadantii",5,"PHE A 182;VAL A 146;ASN A 149;ASP A 189;TRP A 190","None","1.47A","5lg3D-4wfwA:undetectable","5lg3D-4wfwA:14.01"]]