SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wg1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1N4F_A_ASRA141_0
(LYSOZYME C)		 4wg1 LYSOZYME C
(Gallus
gallus) 		6 / 6 ASN A  65
ASP A  66
GLY A  67
THR A  69
PRO A  70
SER A  72
 None
 0.42A 1n4fA-4wg1A:
28.4		 1n4fA-4wg1A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 4wg1 LYSOZYME C
(Gallus
gallus) 		4 / 6 LEU A 129
GLY A 126
LEU A  25
SER A  24
 None
 0.89A 3aiaA-4wg1A:
undetectable		 3aiaA-4wg1A:
21.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 4wg1 LYSOZYME C
(Gallus
gallus) 		3 / 3 ASN A  46
ASP A  52
ASN A  59
 None
 0.19A 4agaA-4wg1A:
28.3		 4agaA-4wg1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4II8_A_010A210_0
(LYSOZYME C)		 4wg1 LYSOZYME C
(Gallus
gallus) 		7 / 7 GLU A  35
ASP A  52
GLN A  57
ASN A  59
TRP A  63
ILE A  98
TRP A 108
 None
None
None
None
None
CL  A 201 ( 4.9A)
CL  A 201 ( 4.3A)
 0.25A 4ii8A-4wg1A:
28.5		 4ii8A-4wg1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DL9_A_ACTA214_0
(LYSOZYME C)		 4wg1 LYSOZYME C
(Gallus
gallus) 		5 / 5 GLU A  35
ASP A  52
TRP A 108
VAL A 109
ALA A 110
 None
None
CL  A 201 ( 4.3A)
None
None
 0.62A 5dl9A-4wg1A:
27.9		 5dl9A-4wg1A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 4wg1 LYSOZYME C
(Gallus
gallus) 		5 / 9 ARG A   5
ALA A   9
GLY A  26
LEU A  25
LEU A 129
 None
 0.98A 5dqfA-4wg1A:
undetectable		 5dqfA-4wg1A:
11.98