SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wgj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 4wgj BEPC PROTEIN
(Bartonella
tribocorum) 		4 / 8 SER A 127
PHE A 131
ALA A 135
LEU A 163
 None
 1.07A 2bxkA-4wgjA:
undetectable		 2bxkA-4wgjA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 4wgj BEPC PROTEIN
(Bartonella
tribocorum) 		4 / 8 HIS A 144
ILE A 102
ARG A  74
PRO A  99
 None
 0.71A 3fxrA-4wgjA:
undetectable		 3fxrA-4wgjA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 4wgj BEPC PROTEIN
(Bartonella
tribocorum) 		4 / 5 PHE A 201
THR A 170
PHE A 131
ILE A 204
 None
None
None
EDO  A 302 (-4.7A)
 0.83A 4jx1E-4wgjA:
undetectable		 4jx1E-4wgjA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4wgj BEPC PROTEIN
(Bartonella
tribocorum) 		6 / 9 LEU A 142
ALA A 141
LEU A 113
LEU A 117
LEU A 163
ALA A 135
 None
 1.23A 4z91F-4wgjA:
undetectable
4z91G-4wgjA:
undetectable
4z91H-4wgjA:
1.7
4z91I-4wgjA:
undetectable
4z91J-4wgjA:
1.6		 4z91F-4wgjA:
18.98
4z91G-4wgjA:
18.98
4z91H-4wgjA:
18.98
4z91I-4wgjA:
18.98
4z91J-4wgjA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EQB_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4wgj BEPC PROTEIN
(Bartonella
tribocorum) 		5 / 12 GLY A 168
GLY A 151
GLY A 153
PHE A  50
THR A 170
 None
ANP  A 301 (-3.1A)
ANP  A 301 (-3.3A)
None
None
 1.07A 5eqbA-4wgjA:
undetectable		 5eqbA-4wgjA:
16.98