SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4whi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 4whi BETA-LACTAMASE
(Mycobacterium
tuberculosis) 		3 / 3 PRO A 444
ASP A 489
ASP A 491
 None
 0.60A 1sqfA-4whiA:
undetectable		 1sqfA-4whiA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 4whi BETA-LACTAMASE
(Mycobacterium
tuberculosis) 		3 / 3 TYR A 451
ASP A 489
ASP A 491
 None
 0.85A 3r24A-4whiA:
undetectable		 3r24A-4whiA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 4whi BETA-LACTAMASE
(Mycobacterium
tuberculosis) 		4 / 6 ARG A 532
ARG A 446
ASP A 491
VAL A 452
 None
 1.27A 4xqeA-4whiA:
undetectable		 4xqeA-4whiA:
16.33