SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4whm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		3 / 3 ALA A 133
VAL A 211
TRP A 135
 None
 0.93A 1bdwA-4whmA:
undetectable
1bdwB-4whmA:
undetectable		 1bdwA-4whmA:
10.43
1bdwB-4whmA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 12 SER A 329
LEU A 246
LEU A  26
LEU A  22
PRO A  19
 None
 1.23A 1p33C-4whmA:
7.4		 1p33C-4whmA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		4 / 8 SER A 198
ALA A 206
LEU A 230
ASP A 114
 None
 1.14A 2bxkA-4whmA:
undetectable		 2bxkA-4whmA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 12 SER A 444
ILE A   9
THR A  35
ALA A  32
VAL A 210
 None
 1.47A 2gl0D-4whmA:
undetectable
2gl0E-4whmA:
undetectable		 2gl0D-4whmA:
16.19
2gl0E-4whmA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		4 / 5 PHE A 395
PHE A 390
PHE A 364
VAL A 269
 None
 1.24A 2lh6A-4whmA:
undetectable		 2lh6A-4whmA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 12 LEU A 289
GLY A 320
VAL A 337
ALA A 299
LEU A 300
 None
None
None
UDP  A1001 ( 3.7A)
None
 1.18A 2oz7A-4whmA:
undetectable		 2oz7A-4whmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		3 / 3 ARG A 194
VAL A 202
THR A 118
 None
 0.67A 3ndtA-4whmA:
undetectable		 3ndtA-4whmA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		6 / 9 GLY A 430
ALA A 432
ASP A 435
ILE A 421
LEU A 239
VAL A 237
 None
 1.45A 3u7sB-4whmA:
undetectable		 3u7sB-4whmA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		4 / 7 PRO A 358
GLY A 356
ALA A 415
ASP A 413
 None
 0.83A 3ur0B-4whmA:
undetectable		 3ur0B-4whmA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 12 PRO A  20
VAL A 274
ALA A 346
SER A 348
MET A 350
 None
UDP  A1001 ( 4.3A)
GOL  A1002 ( 3.4A)
UDP  A1001 (-2.5A)
None
 1.45A 4a84A-4whmA:
undetectable		 4a84A-4whmA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		4 / 7 PRO A 179
ASP A 181
PHE A 192
ASP A 367
 GOL  A1003 (-4.8A)
None
None
GOL  A1002 (-4.0A)
 1.33A 4ndnC-4whmA:
undetectable		 4ndnC-4whmA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		4 / 7 THR A 109
PHE A  37
SER A  36
HIS A   6
 None
None
ACT  A1004 (-2.8A)
None
 1.50A 4o4dA-4whmA:
undetectable		 4o4dA-4whmA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		4 / 6 GLY A 369
ASP A 184
ILE A 148
TYR A 145
 GOL  A1003 (-3.7A)
None
None
None
 1.14A 5iwuA-4whmA:
undetectable		 5iwuA-4whmA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 12 VAL A 275
VAL A 274
ILE A 375
ALA A 372
VAL A 349
 None
UDP  A1001 ( 4.3A)
None
None
None
 1.17A 5n0sB-4whmA:
undetectable		 5n0sB-4whmA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		4 / 5 PHE A  50
PHE A  48
LEU A  18
LEU A 246
 None
 1.37A 5veuH-4whmA:
undetectable		 5veuH-4whmA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 12 VAL A   7
THR A 109
LEU A  28
VAL A 440
SER A 446
 None
 1.17A 6a94B-4whmA:
undetectable		 6a94B-4whmA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE
(Clitoria
ternatea) 		5 / 10 LEU A 144
LEU A 183
ASP A 184
ILE A 370
GLY A 369
 None
None
None
None
GOL  A1003 (-3.7A)
 0.90A 6dm0B-4whmA:
5.0
6dm0C-4whmA:
2.9		 6dm0B-4whmA:
11.94
6dm0C-4whmA:
11.94