SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wia'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4wia PUTATIVE
FLAGELLA-RELATED
PROTEIN H
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE A  32
THR A 186
PHE A 217
ASP A  17
 None
None
None
GOL  A 306 (-3.3A)
 1.33A 4iarA-4wiaA:
undetectable		 4iarA-4wiaA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 4wia PUTATIVE
FLAGELLA-RELATED
PROTEIN H
(Methanocaldococc
us
jannaschii) 		4 / 6 LYS A  18
GLY A  21
TYR A 211
ALA A 207
 GOL  A 306 (-2.5A)
None
None
None
 1.30A 4yshB-4wiaA:
undetectable		 4yshB-4wiaA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 4wia PUTATIVE
FLAGELLA-RELATED
PROTEIN H
(Methanocaldococc
us
jannaschii) 		5 / 12 ARG A  46
PHE A  51
GLY A  21
GLY A  22
MET A 182
 None
 1.12A 6brdB-4wiaA:
undetectable		 6brdB-4wiaA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 4wia PUTATIVE
FLAGELLA-RELATED
PROTEIN H
(Methanocaldococc
us
jannaschii) 		6 / 12 SER A  28
ASN A  54
PHE A  51
GLY A  23
ILE A  30
LEU A  47
 None
 1.42A 6dwnC-4wiaA:
undetectable		 6dwnC-4wiaA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 4wia PUTATIVE
FLAGELLA-RELATED
PROTEIN H
(Methanocaldococc
us
jannaschii) 		6 / 12 SER A  28
ASN A  54
PHE A  51
GLY A  23
ILE A  30
LEU A  47
 None
 1.39A 6dwnD-4wiaA:
undetectable		 6dwnD-4wiaA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4wia PUTATIVE
FLAGELLA-RELATED
PROTEIN H
(Methanocaldococc
us
jannaschii) 		4 / 4 LEU A  16
ASP A  17
ASP A  10
ARG A  46
 None
GOL  A 306 (-3.3A)
GOL  A 306 (-3.9A)
None
 1.31A 6g31E-4wiaA:
undetectable		 6g31E-4wiaA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4wia PUTATIVE
FLAGELLA-RELATED
PROTEIN H
(Methanocaldococc
us
jannaschii) 		4 / 6 LEU A  16
ASP A  17
ASP A  10
ARG A  46
 None
GOL  A 306 (-3.3A)
GOL  A 306 (-3.9A)
None
 1.29A 6g31J-4wiaA:
undetectable		 6g31J-4wiaA:
20.71