SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wid'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4wid RHUL123
(Macacine
betaherpesvirus
3) 		5 / 12 ILE A 119
ALA A 230
GLY A 233
GLY A 235
PHE A 130
 None
None
None
TRS  A 401 ( 4.7A)
None
 0.92A 2okcA-4widA:
undetectable		 2okcA-4widA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4wid RHUL123
(Macacine
betaherpesvirus
3) 		5 / 12 ILE A 119
ALA A 230
GLY A 233
GLY A 235
PHE A 130
 None
None
None
TRS  A 401 ( 4.7A)
None
 0.89A 2okcB-4widA:
undetectable		 2okcB-4widA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4wid RHUL123
(Macacine
betaherpesvirus
3) 		6 / 12 ILE A 119
ALA A 230
GLY A 233
GLY A 235
LEU A 298
PHE A 130
 None
None
None
TRS  A 401 ( 4.7A)
None
None
 1.34A 2y7hB-4widA:
undetectable		 2y7hB-4widA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4wid RHUL123
(Macacine
betaherpesvirus
3) 		6 / 12 ILE A 119
ALA A 230
GLY A 233
GLY A 235
LEU A 298
PHE A 130
 None
None
None
TRS  A 401 ( 4.7A)
None
None
 1.34A 2y7hC-4widA:
2.3		 2y7hC-4widA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 4wid RHUL123
(Macacine
betaherpesvirus
3) 		4 / 5 LEU A  44
GLN A 139
LEU A 137
GLU A 138
 None
 1.10A 3h5gA-4widA:
undetectable
3h5gB-4widA:
undetectable		 3h5gA-4widA:
6.17
3h5gB-4widA:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 4wid RHUL123
(Macacine
betaherpesvirus
3) 		3 / 3 HIS A 245
ASN A 242
LEU A 273
 None
 0.81A 6f7lB-4widA:
undetectable		 6f7lB-4widA:
21.35