SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 4 ARG A 380
ALA A 376
ALA A 313
GLU A 314
None
1.13A 1e7bB-4wj3A:
undetectable
1e7bB-4wj3A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 5 HIS A 468
GLU A 219
ALA A 215
HIS A 477
None
1.39A 1errA-4wj3A:
undetectable
1errB-4wj3A:
undetectable
1errA-4wj3A:
19.88
1errB-4wj3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
4 / 8 GLY M 410
LEU M 295
VAL M 326
PHE M 343
None
1.00A 1gsfC-4wj3M:
undetectable
1gsfC-4wj3M:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
4 / 7 LEU M 155
GLY M 159
LEU M 161
TYR M 213
None
1.06A 1gtiD-4wj3M:
undetectable
1gtiD-4wj3M:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 6 ARG A 178
GLY A 174
ASP A 172
TYR A 307
None
1.42A 1kf6M-4wj3A:
undetectable
1kf6N-4wj3A:
1.4
1kf6M-4wj3A:
21.95
1kf6N-4wj3A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 5 ARG A 321
ASP A 235
SER A 197
SER A 206
None
1.38A 1kiaB-4wj3A:
undetectable
1kiaB-4wj3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 6 ARG A 321
ASP A 235
SER A 197
SER A 206
None
1.37A 1kiaC-4wj3A:
undetectable
1kiaC-4wj3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1872_0
(FPRA)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT C

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 5 ASN B  52
ALA B  55
ASP C  65
GLU B  54
None
1.36A 1lqtA-4wj3B:
undetectable
1lqtB-4wj3B:
undetectable
1lqtA-4wj3B:
22.65
1lqtB-4wj3B:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1429_0
(FPRA)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT C

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 5 ASN B  52
ALA B  55
ASP C  65
GLU B  54
None
1.37A 1lquA-4wj3B:
undetectable
1lquB-4wj3B:
undetectable
1lquA-4wj3B:
22.65
1lquB-4wj3B:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 8 ASP A 209
ILE A 310
GLY A 175
ARG A 178
None
0.94A 1meiA-4wj3A:
undetectable
1meiA-4wj3A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 8 TYR A 425
TYR A 265
GLN A 452
SER A 129
None
1.33A 1nx9C-4wj3A:
undetectable
1nx9C-4wj3A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 8 TYR A 425
TYR A 265
GLN A 452
SER A 129
None
1.33A 1nx9D-4wj3A:
undetectable
1nx9D-4wj3A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 10 LEU A 165
GLY A 155
ALA A 158
SER A  41
LEU A  39
None
1.06A 1pxxA-4wj3A:
undetectable
1pxxA-4wj3A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 LEU A 165
GLY A 155
ALA A 158
SER A  41
LEU A  39
None
1.06A 1pxxC-4wj3A:
undetectable
1pxxC-4wj3A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 11 ALA A 168
ILE A 189
PRO A 180
LEU A 109
VAL A 105
None
1.06A 1rv7A-4wj3A:
undetectable
1rv7B-4wj3A:
undetectable
1rv7A-4wj3A:
13.84
1rv7B-4wj3A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 12 LEU B  61
ALA B  65
LEU B 176
LEU B  15
ILE B  99
None
1.15A 1s9pA-4wj3B:
undetectable
1s9pA-4wj3B:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 12 LEU B  61
ALA B  65
LEU B 176
LEU B  15
ILE B  99
None
1.06A 1s9pD-4wj3B:
undetectable
1s9pD-4wj3B:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_1
(DIHYDROFOLATE
REDUCTASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 ILE A 397
GLN A 459
PRO A 191
LEU A 463
TYR A 265
None
1.50A 1u70A-4wj3A:
undetectable
1u70A-4wj3A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 10 SER M 369
LEU M 367
PHE M 397
PHE M 310
LEU M 380
None
1.50A 1y7iB-4wj3M:
undetectable
1y7iB-4wj3M:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 5 GLY A 137
PRO A 149
VAL A 148
ILE A 409
None
0.81A 2aoiA-4wj3A:
undetectable
2aoiA-4wj3A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 9 LEU B 180
LEU B 176
ILE B 173
PHE B  62
LEU B 152
None
1.14A 2f78A-4wj3B:
undetectable
2f78A-4wj3B:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 9 LEU B 180
LEU B 176
ILE B 173
PHE B  62
LEU B 152
None
1.17A 2f78B-4wj3B:
undetectable
2f78B-4wj3B:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 9 LEU B 180
LEU B 176
ILE B 173
PHE B  62
LEU B 152
None
1.26A 2f7aA-4wj3B:
undetectable
2f7aA-4wj3B:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 6 TYR A 308
GLY A 128
TYR A 307
ASP A 123
None
1.16A 2g72A-4wj3A:
undetectable
2g72A-4wj3A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 MET A 228
ALA A  56
ALA A  54
THR A  25
ILE A  74
None
1.29A 2jjpA-4wj3A:
undetectable
2jjpA-4wj3A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 7 GLY A 200
THR B  47
MET A 201
SER A 206
None
1.12A 2o5yH-4wj3A:
undetectable
2o5yL-4wj3A:
undetectable
2o5yH-4wj3A:
18.80
2o5yL-4wj3A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
3 / 3 SER A 152
HIS A  76
ASP A 102
None
0.74A 2oxtA-4wj3A:
undetectable
2oxtA-4wj3A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 11 LEU M 484
PHE M 534
LEU M 539
LEU M 263
VAL M 262
None
1.29A 2po5B-4wj3M:
undetectable
2po5B-4wj3M:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
3 / 3 LEU M 384
ARG M 325
ILE M 383
None
0.68A 2xn5B-4wj3M:
undetectable
2xn5B-4wj3M:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
3 / 3 LEU B 320
TRP B 346
TYR B 329
None
0.91A 3aicA-4wj3B:
undetectable
3aicA-4wj3B:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
3 / 3 LEU B 320
TRP B 346
TYR B 329
None
0.95A 3aicB-4wj3B:
undetectable
3aicB-4wj3B:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
3 / 3 LEU B 320
TRP B 346
TYR B 329
None
0.95A 3aicE-4wj3B:
undetectable
3aicE-4wj3B:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
3 / 3 LEU B 320
TRP B 346
TYR B 329
None
0.96A 3aicF-4wj3B:
undetectable
3aicF-4wj3B:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
3 / 3 LEU B 320
TRP B 346
TYR B 329
None
0.94A 3aicG-4wj3B:
undetectable
3aicG-4wj3B:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
3 / 3 LEU B 320
TRP B 346
TYR B 329
None
0.97A 3aicH-4wj3B:
undetectable
3aicH-4wj3B:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 4 THR A 171
VAL A 105
GLY B  46
THR B  47
None
1.08A 3cflA-4wj3A:
2.0
3cflA-4wj3A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 7 TYR A 307
GLY A 174
TYR A 193
ARG A 380
None
0.92A 3elzA-4wj3A:
0.5
3elzA-4wj3A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT C

(Pseudomonas
aeruginosa)
5 / 11 ARG A 381
GLN C  42
PRO A 305
ILE A 383
ILE A 310
None
1.24A 3ganA-4wj3A:
undetectable
3ganA-4wj3A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
3 / 3 MET B 348
MET B 375
PHE B 330
None
1.39A 3gn8A-4wj3B:
undetectable
3gn8A-4wj3B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
3 / 3 SER A 176
ASP A 423
ASP A 209
None
0.89A 3iv6A-4wj3A:
undetectable
3iv6A-4wj3A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
3 / 3 SER A 176
ASP A 423
ASP A 209
None
0.87A 3iv6C-4wj3A:
undetectable
3iv6C-4wj3A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 GLU A 314
GLY A 194
ARG A 380
GLY A 174
ARG A 178
None
1.39A 3jzjA-4wj3A:
1.7
3jzjA-4wj3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 10 VAL B 333
GLY B 338
VAL B 367
ILE B 379
GLY B 373
None
1.29A 3km6A-4wj3B:
undetectable
3km6A-4wj3B:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
3 / 3 LEU A 447
TRP A 143
GLY A 483
None
0.76A 3l35A-4wj3A:
undetectable
3l35H-4wj3A:
undetectable
3l35A-4wj3A:
7.52
3l35H-4wj3A:
2.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 LEU A 165
GLY A 155
ALA A 158
SER A  41
LEU A  39
None
1.04A 3n8xB-4wj3A:
undetectable
3n8xB-4wj3A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
3 / 3 ASP B 277
GLU B 126
SER A 197
None
0.85A 3p2kA-4wj3B:
undetectable
3p2kA-4wj3B:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT C

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 4 LEU C  87
GLY B 141
LEU B 132
GLU B 134
None
1.08A 3tgvB-4wj3C:
undetectable
3tgvB-4wj3C:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 9 ASN A 131
GLY A 154
GLY A 155
ASN A  40
GLY A 150
None
1.05A 3ztvA-4wj3A:
undetectable
3ztvA-4wj3A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 PHE M 438
PRO M 456
PRO M 452
ILE M 506
ALA M 499
None
1.32A 4a83A-4wj3M:
undetectable
4a83A-4wj3M:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT C

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
5 / 12 PHE A 349
PHE A 125
LEU C  31
ALA A 315
SER A 316
None
1.28A 4a83A-4wj3A:
undetectable
4a83A-4wj3A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
3 / 3 GLU M 244
TYR M 475
SER M 488
None
0.90A 4at0A-4wj3M:
undetectable
4at0A-4wj3M:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
3 / 3 ARG A 380
ARG A 381
ILE A 310
None
0.94A 4b7qA-4wj3A:
undetectable
4b7qA-4wj3A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
3 / 3 ARG A 380
ARG A 381
ILE A 310
None
0.87A 4b7qC-4wj3A:
undetectable
4b7qC-4wj3A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 LEU A 165
GLY A 155
ALA A 158
SER A  41
LEU A  39
None
1.06A 4coxC-4wj3A:
undetectable
4coxC-4wj3A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT C

(Pseudomonas
aeruginosa)
4 / 7 LEU C  17
ARG C  16
GLY A 360
SER A 316
None
0.80A 4cp3A-4wj3C:
undetectable
4cp3B-4wj3C:
undetectable
4cp3A-4wj3C:
22.79
4cp3B-4wj3C:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLU M 306
LEU M 302
ALA M 314
GLU M 304
ASN M 315
None
1.46A 4cpzB-4wj3M:
undetectable
4cpzB-4wj3M:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 12 VAL B 155
PRO B 158
ILE B 223
VAL B 170
ILE B 107
None
1.27A 4eb6B-4wj3B:
undetectable
4eb6C-4wj3B:
undetectable
4eb6B-4wj3B:
19.93
4eb6C-4wj3B:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 11 TYR M 212
LEU M 204
VAL M 163
ALA M 216
PHE M 200
None
1.20A 4evrA-4wj3M:
undetectable
4evrA-4wj3M:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 LEU A 270
TYR A 425
PRO A 405
ALA A 182
GLY A 442
None
1.07A 4j7xB-4wj3A:
undetectable
4j7xB-4wj3A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.01A 4jksA-4wj3M:
undetectable
4jksA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.02A 4jksB-4wj3M:
undetectable
4jksB-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.00A 4jkuA-4wj3M:
undetectable
4jkuA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
4 / 8 ARG M 220
PHE M 232
GLY M 485
ARG M 538
None
1.01A 4k87A-4wj3M:
11.3
4k87A-4wj3M:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.01A 4k8cA-4wj3M:
undetectable
4k8cA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.01A 4k8cB-4wj3M:
undetectable
4k8cB-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.02A 4k8kA-4wj3M:
undetectable
4k8kA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.02A 4k8kB-4wj3M:
undetectable
4k8kB-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.01A 4kahA-4wj3M:
undetectable
4kahA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.01A 4kahB-4wj3M:
undetectable
4kahB-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.02A 4kalA-4wj3M:
undetectable
4kalA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.01A 4kalB-4wj3M:
undetectable
4kalB-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.02A 4kanA-4wj3M:
undetectable
4kanA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.02A 4kanB-4wj3M:
undetectable
4kanB-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.00A 4kbeA-4wj3M:
undetectable
4kbeA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.02A 4kbeB-4wj3M:
undetectable
4kbeB-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 11 SER A 153
GLY A 151
GLY A 175
ILE A 259
LEU A 257
None
0.83A 4kt0A-4wj3A:
undetectable
4kt0J-4wj3A:
undetectable
4kt0A-4wj3A:
22.05
4kt0J-4wj3A:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 12 PHE B  62
ALA B  59
MET B  58
LEU B 176
LEU B 192
None
1.27A 4kykA-4wj3B:
undetectable
4kykB-4wj3B:
undetectable
4kykA-4wj3B:
20.98
4kykB-4wj3B:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.02A 4lbgA-4wj3M:
undetectable
4lbgA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.03A 4lbgB-4wj3M:
undetectable
4lbgB-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.02A 4lcaA-4wj3M:
undetectable
4lcaA-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 487
GLY M 486
ILE M 237
GLU M 483
THR M 251
None
1.00A 4lcaB-4wj3M:
undetectable
4lcaB-4wj3M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 8 SER A 197
ASP A 232
MET B  44
THR B  47
None
1.10A 4lnwA-4wj3A:
undetectable
4lnwA-4wj3A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 8 ASP A 209
ALA A 126
SER A 152
TYR A 204
None
1.04A 4lv9A-4wj3A:
undetectable
4lv9B-4wj3A:
undetectable
4lv9A-4wj3A:
22.53
4lv9B-4wj3A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 7 TYR A 204
ASP A 209
ALA A 126
SER A 152
None
1.01A 4lv9A-4wj3A:
undetectable
4lv9B-4wj3A:
undetectable
4lv9A-4wj3A:
22.53
4lv9B-4wj3A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 4 HIS A   3
GLU A   9
HIS A 477
LEU A 186
None
1.35A 4m2rA-4wj3A:
undetectable
4m2rA-4wj3A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
4 / 7 GLN M  47
VAL M  49
GLU M  94
ARG M  77
U  Q  35 ( 3.4A)
None
G  Q  34 ( 2.7A)
G  Q  34 ( 3.6A)
1.27A 4mv7A-4wj3M:
undetectable
4mv7A-4wj3M:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 5 LEU B  48
ARG B  78
ARG A 321
THR A 104
None
1.33A 4p3qA-4wj3B:
undetectable
4p3qA-4wj3B:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
3 / 3 ILE A 427
ASP A 172
ARG A 380
None
0.52A 4pstA-4wj3A:
undetectable
4pstA-4wj3A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 TYR A 307
ASN A 318
LEU A 208
LEU A 431
ALA A 376
None
1.13A 4rtbA-4wj3A:
undetectable
4rtbA-4wj3A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 LEU A  70
ALA A  11
LEU A   7
MET A 224
ILE A  74
None
1.12A 4x1yB-4wj3A:
undetectable
4x1yB-4wj3A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 LEU A 214
ALA A 168
LEU A 165
LEU A 120
MET A 201
None
0.91A 4xi3C-4wj3A:
undetectable
4xi3C-4wj3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 12 GLY M 531
GLY M 530
THR M 239
ILE M 237
ILE M 248
None
1.18A 4zvmA-4wj3M:
undetectable
4zvmB-4wj3M:
undetectable
4zvmA-4wj3M:
17.29
4zvmB-4wj3M:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 7 ASP A 209
GLY A 170
THR A 173
LYS A  77
None
1.02A 4zxiA-4wj3A:
undetectable
4zxiA-4wj3A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
3 / 3 PRO A 180
LEU A 120
SER A 176
None
0.83A 5fsaB-4wj3A:
1.1
5fsaB-4wj3A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 ALA A 218
PRO A 213
GLY A 436
THR A 426
GLU A 460
None
1.34A 5hfjC-4wj3A:
undetectable
5hfjC-4wj3A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 12 TYR A 101
TYR A 327
LEU A  94
ILE A 202
GLY B  46
None
1.16A 5ifuA-4wj3A:
undetectable
5ifuA-4wj3A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 9 TYR A 101
TYR A 327
LEU A  94
ILE A 202
GLY B  46
None
1.28A 5ifuB-4wj3A:
undetectable
5ifuB-4wj3A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
5 / 12 ASP B 277
SER A 206
ASN A 318
GLU A 314
VAL B  75
None
1.38A 5iqdC-4wj3B:
undetectable
5iqdC-4wj3B:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_A_ASCA502_0
(OS09G0567300 PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
4 / 5 GLU M 107
PRO M 110
PHE M 129
ARG M 133
None
1.16A 5jcnA-4wj3M:
undetectable
5jcnA-4wj3M:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
4 / 6 GLU M 107
PRO M 110
PHE M 129
ARG M 133
None
1.15A 5jcnB-4wj3M:
undetectable
5jcnB-4wj3M:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
3 / 3 VAL B 319
GLU B 325
GLU B 363
None
0.91A 5jsdB-4wj3B:
undetectable
5jsdC-4wj3B:
undetectable
5jsdB-4wj3B:
18.39
5jsdC-4wj3B:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa)
4 / 6 ARG B  78
CYH A  81
THR A  87
PHE A  97
None
1.41A 5mwyA-4wj3B:
undetectable
5mwyA-4wj3B:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
4 / 6 ASP M 537
LEU M 536
GLY M 535
PHE M 534
None
0.90A 5nooC-4wj3M:
undetectable
5nooC-4wj3M:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 10 ILE B  11
ILE B 173
VAL B 177
PHE B  62
ALA B  59
None
1.15A 5nukA-4wj3B:
undetectable
5nukA-4wj3B:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 11 LEU B 124
PRO B 150
GLU B  53
LEU B 152
ALA B  59
None
1.02A 5o96A-4wj3B:
undetectable
5o96B-4wj3B:
undetectable
5o96A-4wj3B:
21.48
5o96B-4wj3B:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 9 LEU M  21
HIS M   5
GLY M   8
VAL M  76
ARG M  79
None
None
None
None
U  Q  36 ( 3.6A)
1.19A 5o96E-4wj3M:
2.1
5o96F-4wj3M:
undetectable
5o96E-4wj3M:
18.94
5o96F-4wj3M:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
5 / 9 LEU A 120
GLY A 170
SER A  41
VAL A 160
LEU A 165
None
1.31A 5o96E-4wj3A:
undetectable
5o96F-4wj3A:
undetectable
5o96E-4wj3A:
18.90
5o96F-4wj3A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 7 ARG A 195
LEU A 109
THR A 171
ARG A 198
None
1.01A 5vc0A-4wj3A:
undetectable
5vc0A-4wj3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 9 GLY M 388
LEU M 302
VAL M 298
PHE M 310
ILE M 371
None
0.95A 5vkqC-4wj3M:
undetectable
5vkqD-4wj3M:
undetectable
5vkqC-4wj3M:
15.27
5vkqD-4wj3M:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
3 / 3 ARG M 320
PHE M 396
LEU M 295
None
0.76A 5x1bC-4wj3M:
undetectable
5x1bC-4wj3M:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
4 / 7 GLU M 513
ARG M 170
THR M 172
PRO M 173
None
1.38A 6a4iB-4wj3M:
undetectable
6a4iB-4wj3M:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
4 / 4 GLY A 433
ARG A 178
ASN A 430
LEU A 434
None
1.11A 6b58A-4wj3A:
undetectable
6b58A-4wj3A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 10 PHE M 232
GLU M 483
GLY M 535
ARG M 538
ILE M 549
None
1.13A 6bniA-4wj3M:
12.5
6bniA-4wj3M:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa)
5 / 10 PHE M 232
GLU M 483
GLY M 535
ARG M 538
ILE M 549
None
1.10A 6bniB-4wj3M:
25.7
6bniB-4wj3M:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Pseudomonas
aeruginosa)
5 / 12 ASP B  67
ALA B  65
LEU B 176
ALA B 172
LEU B 298
None
0.90A 6bq4A-4wj3B:
undetectable
6bq4A-4wj3B:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT C

(Pseudomonas
aeruginosa)
4 / 5 VAL A 239
LEU B 279
VAL B 282
LEU C  62
None
0.85A 6bqgA-4wj3A:
undetectable
6bqgA-4wj3A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa)
3 / 3 ARG A 147
LEU A 447
PHE A 443
None
0.73A 6nknP-4wj3A:
undetectable
6nknP-4wj3A:
19.59