SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wjb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 0.97A 1c8lA-4wjbA:
undetectable		 1c8lA-4wjbA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 12 THR A 399
ALA A 402
ASP A 403
LEU A 406
ILE A 101
 None
 1.14A 1errA-4wjbA:
undetectable		 1errA-4wjbA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 0.99A 1gfzA-4wjbA:
undetectable		 1gfzA-4wjbA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 0.96A 1l5qA-4wjbA:
undetectable		 1l5qA-4wjbA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 1.00A 1l7xA-4wjbA:
undetectable		 1l7xA-4wjbA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 0.99A 1l7xB-4wjbA:
undetectable		 1l7xB-4wjbA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		3 / 3 PHE A 148
VAL A 368
TRP A 130
 None
None
EDO  A 506 (-4.2A)
 0.89A 2ccbA-4wjbA:
2.8		 2ccbA-4wjbA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 12 VAL A  11
THR A 208
ALA A 400
ASP A 403
ARG A  10
 None
 0.95A 2qm9A-4wjbA:
undetectable		 2qm9A-4wjbA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		3 / 3 PHE A 148
VAL A 368
TRP A 130
 None
None
EDO  A 506 (-4.2A)
 0.90A 2vx9A-4wjbA:
2.8		 2vx9A-4wjbA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 113
GLU A 109
ARG A  15
GLY A  13
THR A 399
 None
 1.14A 2xffA-4wjbA:
undetectable		 2xffA-4wjbA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 5 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 0.95A 3bcrA-4wjbA:
undetectable		 3bcrA-4wjbA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 1.01A 3dd1A-4wjbA:
undetectable		 3dd1A-4wjbA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 1.00A 3dd1B-4wjbA:
undetectable		 3dd1B-4wjbA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 1.00A 3ddsA-4wjbA:
undetectable		 3ddsA-4wjbA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 1.00A 3ddwA-4wjbA:
undetectable		 3ddwA-4wjbA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		3 / 3 TYR A 367
TYR A 152
GLU A 133
 None
None
ZN  A 501 ( 4.1A)
 0.96A 3pfgA-4wjbA:
undetectable		 3pfgA-4wjbA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 12 GLU A 203
GLY A 384
ASP A  99
ILE A 196
GLY A 199
 None
None
ZN  A 501 (-1.8A)
None
None
 1.38A 3ps9A-4wjbA:
2.5		 3ps9A-4wjbA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		3 / 3 GLU A 197
PHE A 378
GLN A 198
 None
None
ZN  A 501 (-4.0A)
 1.00A 3r55A-4wjbA:
undetectable		 3r55A-4wjbA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 GLY A 135
PRO A 140
GLY A 157
TYR A 152
 None
 0.75A 4dxuA-4wjbA:
undetectable		 4dxuA-4wjbA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 10 ILE A 101
ALA A  89
GLU A 133
GLY A  67
ASN A  68
 None
None
ZN  A 501 ( 4.1A)
None
None
 1.49A 4e47D-4wjbA:
0.0		 4e47D-4wjbA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 7 HIS A 387
ASP A  99
GLU A 134
GLU A 133
 ZN  A 501 (-2.8A)
ZN  A 501 (-1.8A)
ZN  A 501 (-1.8A)
ZN  A 501 ( 4.1A)
 0.99A 4hvrA-4wjbA:
undetectable		 4hvrA-4wjbA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 11 ILE A 101
ALA A  89
GLU A 133
GLY A  67
ASN A  68
 None
None
ZN  A 501 ( 4.1A)
None
None
 1.49A 4j83A-4wjbA:
undetectable		 4j83A-4wjbA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 11 ILE A 101
ALA A  89
GLU A 133
GLY A  67
ASN A  68
 None
None
ZN  A 501 ( 4.1A)
None
None
 1.42A 4jlgB-4wjbA:
undetectable		 4jlgB-4wjbA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 8 THR A 121
THR A  85
LEU A 114
VAL A 110
 None
 0.96A 4l4aA-4wjbA:
undetectable		 4l4aA-4wjbA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 8 THR A 121
THR A  85
LEU A 114
VAL A 110
 None
 1.00A 4l4eA-4wjbA:
undetectable		 4l4eA-4wjbA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 8 THR A 121
THR A  85
LEU A 114
VAL A 110
 None
 0.99A 4l4fA-4wjbA:
undetectable		 4l4fA-4wjbA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 12 ASP A  64
VAL A 183
GLY A  67
PHE A 138
GLY A 157
 None
 1.35A 4pevB-4wjbA:
undetectable		 4pevB-4wjbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 11 GLY A 103
GLY A 106
VAL A 127
ASP A 364
ILE A 101
 None
 1.13A 4pghA-4wjbA:
undetectable		 4pghA-4wjbA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		6 / 11 HIS A  88
ASP A  99
GLU A 133
GLU A 134
GLY A 360
HIS A 387
 ZN  A 501 (-3.3A)
ZN  A 501 (-1.8A)
ZN  A 501 ( 4.1A)
ZN  A 501 (-1.8A)
None
ZN  A 501 (-2.8A)
 0.59A 4pqaA-4wjbA:
29.3		 4pqaA-4wjbA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		6 / 12 THR A 399
ALA A 402
ASP A 403
LEU A 406
LEU A 105
PRO A   9
 None
 1.42A 4xi3A-4wjbA:
undetectable		 4xi3A-4wjbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		6 / 12 THR A 399
ALA A 402
ASP A 403
LEU A 406
LEU A 105
PRO A   9
 None
 1.46A 4xi3B-4wjbA:
undetectable		 4xi3B-4wjbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 7 ALA A  28
GLU A  21
GLY A  32
GLY A  96
 None
 0.88A 5e26A-4wjbA:
undetectable
5e26B-4wjbA:
undetectable		 5e26A-4wjbA:
21.76
5e26B-4wjbA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 7 GLU A  21
GLY A  32
GLY A  96
ALA A  28
 None
 0.88A 5e26C-4wjbA:
undetectable
5e26D-4wjbA:
undetectable		 5e26C-4wjbA:
21.76
5e26D-4wjbA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 408
VAL A 343
GLY A 401
GLU A 109
ALA A 400
 None
 1.19A 5n5dA-4wjbA:
undetectable		 5n5dA-4wjbA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		5 / 12 ALA A 408
VAL A 343
GLY A 401
TYR A 192
ALA A 400
 None
 1.15A 5n5dA-4wjbA:
undetectable		 5n5dA-4wjbA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 ASP A  99
HIS A 195
HIS A  88
HIS A 387
 ZN  A 501 (-1.8A)
ZN  A 501 (-3.3A)
ZN  A 501 (-3.3A)
ZN  A 501 (-2.8A)
 0.92A 5ncdA-4wjbA:
undetectable
5ncdD-4wjbA:
undetectable		 5ncdA-4wjbA:
21.75
5ncdD-4wjbA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 ASP A  99
HIS A 195
HIS A  88
HIS A 387
 ZN  A 501 (-1.8A)
ZN  A 501 (-3.3A)
ZN  A 501 (-3.3A)
ZN  A 501 (-2.8A)
 0.88A 5ncdB-4wjbA:
undetectable
5ncdC-4wjbA:
undetectable		 5ncdB-4wjbA:
21.75
5ncdC-4wjbA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 8 ASP A  99
HIS A 195
HIS A  88
HIS A 387
 ZN  A 501 (-1.8A)
ZN  A 501 (-3.3A)
ZN  A 501 (-3.3A)
ZN  A 501 (-2.8A)
 0.94A 5nekB-4wjbA:
undetectable		 5nekB-4wjbA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 8 ASP A  99
HIS A 195
HIS A  88
HIS A 387
 ZN  A 501 (-1.8A)
ZN  A 501 (-3.3A)
ZN  A 501 (-3.3A)
ZN  A 501 (-2.8A)
 0.89A 5nekD-4wjbA:
undetectable		 5nekD-4wjbA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 ASP A  99
HIS A 195
HIS A  88
HIS A 387
 ZN  A 501 (-1.8A)
ZN  A 501 (-3.3A)
ZN  A 501 (-3.3A)
ZN  A 501 (-2.8A)
 0.93A 5nelA-4wjbA:
undetectable
5nelD-4wjbA:
undetectable		 5nelA-4wjbA:
21.75
5nelD-4wjbA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 4 THR A  40
ASP A  43
ARG A  36
LEU A  37
 None
 1.25A 5tdmA-4wjbA:
1.8		 5tdmA-4wjbA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		3 / 3 GLU A 155
TYR A 156
ARG A 160
 None
 0.70A 5uunA-4wjbA:
undetectable		 5uunA-4wjbA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		3 / 3 GLU A 155
TYR A 156
ARG A 160
 None
 0.73A 5uunB-4wjbA:
undetectable		 5uunB-4wjbA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		4 / 6 GLU A 197
HIS A 363
ALA A 361
GLN A 216
 None
None
SO4  A 503 ( 4.9A)
None
 1.47A 6f6jC-4wjbA:
undetectable
6f6jD-4wjbA:
undetectable		 6f6jC-4wjbA:
23.57
6f6jD-4wjbA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE
(Burkholderia
cenocepacia) 		3 / 3 ARG A  97
GLY A  32
GLU A 389
 None
 0.62A 6fgdA-4wjbA:
undetectable		 6fgdA-4wjbA:
22.24