SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 8 SER A 100
HIS A 193
SER A 189
HIS A 190
 NAP  A 301 ( 2.6A)
TYR  A 302 ( 4.9A)
TYR  A 302 ( 3.8A)
None
 1.31A 1eqbC-4wjiA:
undetectable
1eqbD-4wjiA:
undetectable		 1eqbC-4wjiA:
22.77
1eqbD-4wjiA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 6 ASP A  97
VAL A  95
ILE A  94
TRP A 166
 None
 0.97A 1s9qA-4wjiA:
undetectable		 1s9qA-4wjiA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 8 SER A 100
HIS A 193
SER A 189
HIS A 190
 NAP  A 301 ( 2.6A)
TYR  A 302 ( 4.9A)
TYR  A 302 ( 3.8A)
None
 1.31A 2vmyA-4wjiA:
3.6
2vmyB-4wjiA:
4.3		 2vmyA-4wjiA:
23.86
2vmyB-4wjiA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 ASP A  53
ILE A  24
VAL A  70
THR A  37
 None
None
None
NAP  A 301 (-3.1A)
 1.07A 3eigA-4wjiA:
1.4		 3eigA-4wjiA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 PRO A 124
GLY A  12
ALA A 135
GLY A 136
ILE A  13
 NAP  A 301 (-4.6A)
NAP  A 301 (-3.4A)
None
None
None
 0.94A 3ku1A-4wjiA:
2.2		 3ku1A-4wjiA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 PHE A 165
VAL A  70
ILE A   8
SER A  19
 None
 0.89A 3pglA-4wjiA:
2.2		 3pglA-4wjiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 8 ALA A  21
ILE A  33
LEU A  10
ALA A  46
 None
 0.71A 3r9tA-4wjiA:
undetectable		 3r9tA-4wjiA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 ILE A 106
GLY A 103
VAL A 120
THR A 149
GLY A 122
 None
 1.33A 4acaB-4wjiA:
3.8
4acaC-4wjiA:
4.0		 4acaB-4wjiA:
22.09
4acaC-4wjiA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 9 ALA A  66
VAL A  71
ALA A  59
ALA A  62
ILE A  11
 None
 1.07A 4lbgB-4wjiA:
4.2		 4lbgB-4wjiA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 PRO A 151
ASP A 177
HIS A 123
HIS A 181
GLY A 122
 None
None
TYR  A 302 (-3.7A)
None
None
 1.32A 4lxzB-4wjiA:
undetectable		 4lxzB-4wjiA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 7 SER A  18
ALA A  21
GLY A  52
VAL A  35
 None
 0.87A 5fpdA-4wjiA:
undetectable		 5fpdA-4wjiA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A   9
ILE A  20
GLY A  17
THR A  37
LEU A  68
 None
None
None
NAP  A 301 (-3.1A)
None
 1.22A 5nfjB-4wjiA:
undetectable		 5nfjB-4wjiA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 12 ALA A   9
ILE A  20
GLY A  17
THR A  37
LEU A  68
 None
None
None
NAP  A 301 (-3.1A)
None
 1.22A 5nfjC-4wjiA:
undetectable		 5nfjC-4wjiA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		4 / 5 LEU A 162
THR A  96
THR A 149
GLY A 122
 None
 1.12A 6gtqA-4wjiA:
undetectable		 6gtqA-4wjiA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE
(Sinorhizobium
meliloti) 		5 / 11 SER A 189
GLY A 122
GLY A  99
ASP A  97
VAL A 105
 TYR  A 302 ( 3.8A)
None
NAP  A 301 (-3.4A)
None
None
 1.26A 6i5zD-4wjiA:
4.3		 6i5zD-4wjiA:
22.11