SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wjl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 ILE A 108
HIS A 504
LEU A 490
VAL A  94
 None
 0.82A 1fslB-4wjlA:
undetectable		 1fslB-4wjlA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 5 LEU A 575
TRP A 584
LEU A 565
GLN A 548
 None
 1.48A 1p93D-4wjlA:
undetectable		 1p93D-4wjlA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		3 / 3 VAL A 674
ALA A 675
HIS A 734
 None
 0.74A 1q23G-4wjlA:
undetectable		 1q23G-4wjlA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_1
(HYPOTHETICAL PROTEIN
PH0226)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 4 TYR A 477
ARG A 450
ASP A 600
ASP A 626
 None
 1.49A 1ve3A-4wjlA:
undetectable		 1ve3A-4wjlA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLY A 654
ILE A 566
ILE A 721
SER A 672
PHE A 777
 None
 1.09A 1ve3B-4wjlA:
undetectable		 1ve3B-4wjlA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_1
(HYPOTHETICAL PROTEIN
PH0226)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 4 TYR A 477
ARG A 450
ASP A 600
ASP A 626
 None
 1.48A 1ve3B-4wjlA:
undetectable		 1ve3B-4wjlA:
16.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 233
GLU A 234
TYR A 683
VAL A 730
HIS A 759
 None
 0.75A 1x70A-4wjlA:
41.3		 1x70A-4wjlA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 233
GLU A 234
TYR A 683
VAL A 730
HIS A 759
 None
 0.75A 1x70B-4wjlA:
40.9		 1x70B-4wjlA:
36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 5 PRO A 275
PRO A 267
ILE A 266
GLY A 277
 None
 0.95A 2jkjD-4wjlA:
undetectable		 2jkjD-4wjlA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 5 PRO A 275
PRO A 267
ILE A 266
GLY A 277
 None
 0.95A 2jkjF-4wjlA:
undetectable		 2jkjF-4wjlA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 6 MET A 362
LEU A 368
GLU A 373
MET A 386
 None
 1.11A 2kuhA-4wjlA:
undetectable		 2kuhA-4wjlA:
6.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		6 / 12 GLU A 233
GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.68A 2rguA-4wjlA:
41.2		 2rguA-4wjlA:
36.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 11 GLU A 233
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.63A 2rguB-4wjlA:
41.0		 2rguB-4wjlA:
36.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 11 GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.57A 2rguB-4wjlA:
41.0		 2rguB-4wjlA:
36.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 TYR A 453
ARG A 463
ARG A 450
HIS A 400
 None
 1.40A 2vxaA-4wjlA:
undetectable
2vxaC-4wjlA:
undetectable
2vxaE-4wjlA:
undetectable		 2vxaA-4wjlA:
7.23
2vxaC-4wjlA:
7.23
2vxaE-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 ARG A 450
TYR A 453
ARG A 463
HIS A 400
 None
 1.43A 2vxaA-4wjlA:
undetectable
2vxaB-4wjlA:
undetectable
2vxaK-4wjlA:
undetectable		 2vxaA-4wjlA:
7.23
2vxaB-4wjlA:
7.23
2vxaK-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 ARG A 450
TYR A 453
ARG A 463
HIS A 400
 None
 1.42A 2vxaB-4wjlA:
undetectable
2vxaC-4wjlA:
undetectable
2vxaG-4wjlA:
undetectable		 2vxaB-4wjlA:
7.23
2vxaC-4wjlA:
7.23
2vxaG-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 TYR A 453
ARG A 463
ARG A 450
HIS A 400
 None
 1.41A 2vxaD-4wjlA:
undetectable
2vxaF-4wjlA:
undetectable
2vxaI-4wjlA:
undetectable		 2vxaD-4wjlA:
7.23
2vxaF-4wjlA:
7.23
2vxaI-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 ARG A 450
TYR A 453
ARG A 463
HIS A 400
 None
 1.44A 2vxaD-4wjlA:
undetectable
2vxaE-4wjlA:
undetectable
2vxaL-4wjlA:
undetectable		 2vxaD-4wjlA:
7.23
2vxaE-4wjlA:
7.23
2vxaL-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 HIS A 400
ARG A 450
TYR A 453
ARG A 463
 None
 1.42A 2vxaB-4wjlA:
undetectable
2vxaG-4wjlA:
undetectable
2vxaH-4wjlA:
undetectable		 2vxaB-4wjlA:
7.23
2vxaG-4wjlA:
7.23
2vxaH-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 ARG A 450
TYR A 453
ARG A 463
HIS A 400
 None
 1.44A 2vxaH-4wjlA:
undetectable
2vxaI-4wjlA:
undetectable
2vxaJ-4wjlA:
undetectable		 2vxaH-4wjlA:
7.23
2vxaI-4wjlA:
7.23
2vxaJ-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 HIS A 400
TYR A 453
ARG A 463
ARG A 450
 None
 1.44A 2vxaD-4wjlA:
undetectable
2vxaJ-4wjlA:
undetectable
2vxaL-4wjlA:
undetectable		 2vxaD-4wjlA:
7.23
2vxaJ-4wjlA:
7.23
2vxaL-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 HIS A 400
ARG A 450
TYR A 453
ARG A 463
 None
 1.45A 2vxaH-4wjlA:
undetectable
2vxaJ-4wjlA:
undetectable
2vxaK-4wjlA:
undetectable		 2vxaH-4wjlA:
7.23
2vxaJ-4wjlA:
7.23
2vxaK-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 HIS A 400
ARG A 450
TYR A 453
ARG A 463
 None
 1.44A 2vxaA-4wjlA:
undetectable
2vxaK-4wjlA:
undetectable
2vxaL-4wjlA:
undetectable		 2vxaA-4wjlA:
7.23
2vxaK-4wjlA:
7.23
2vxaL-4wjlA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 7 TYR A 282
ASN A 760
TYR A 683
LYS A 650
 None
 1.42A 2w98A-4wjlA:
undetectable
2w98B-4wjlA:
undetectable		 2w98A-4wjlA:
20.03
2w98B-4wjlA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		3 / 3 LEU A 211
TYR A 202
GLN A 203
 None
 0.73A 2wekA-4wjlA:
2.7		 2wekA-4wjlA:
20.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 233
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.67A 3bjmA-4wjlA:
41.2		 3bjmA-4wjlA:
36.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.53A 3bjmA-4wjlA:
41.2		 3bjmA-4wjlA:
36.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		6 / 12 GLU A 233
GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.68A 3g0bA-4wjlA:
41.2		 3g0bA-4wjlA:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		6 / 12 GLU A 233
GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.71A 3g0bB-4wjlA:
40.9		 3g0bB-4wjlA:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		6 / 12 GLU A 233
GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.69A 3g0bC-4wjlA:
41.0		 3g0bC-4wjlA:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 233
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.65A 3g0bD-4wjlA:
40.9		 3g0bD-4wjlA:
36.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.59A 3g0bD-4wjlA:
40.9		 3g0bD-4wjlA:
36.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G59_A_ACTA306_0
(FMN
ADENYLYLTRANSFERASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 5 SER A 502
MET A 471
PHE A 470
ILE A 514
 None
 1.19A 3g59A-4wjlA:
undetectable		 3g59A-4wjlA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 7 GLY A 393
PHE A 606
PHE A 398
GLY A 421
 None
 0.97A 3ko0M-4wjlA:
undetectable
3ko0P-4wjlA:
undetectable		 3ko0M-4wjlA:
8.90
3ko0P-4wjlA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 GLY A 393
PHE A 606
PHE A 398
GLY A 421
 None
 0.97A 3ko0O-4wjlA:
undetectable
3ko0Q-4wjlA:
undetectable		 3ko0O-4wjlA:
8.90
3ko0Q-4wjlA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 7 PHE A 398
GLY A 421
GLY A 393
PHE A 606
 None
 0.95A 3ko0M-4wjlA:
undetectable
3ko0P-4wjlA:
undetectable		 3ko0M-4wjlA:
8.90
3ko0P-4wjlA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_A_VIBA191_1
(THIT)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 10 GLU A 569
HIS A 759
GLY A 724
TYR A 754
VAL A 761
 None
 1.42A 3rlbA-4wjlA:
0.0		 3rlbA-4wjlA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 569
HIS A 759
GLY A 724
TYR A 754
VAL A 761
 None
 1.43A 3rlbB-4wjlA:
undetectable		 3rlbB-4wjlA:
14.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 233
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.66A 3w2tA-4wjlA:
40.9		 3w2tA-4wjlA:
36.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.50A 3w2tA-4wjlA:
40.9		 3w2tA-4wjlA:
36.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 233
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.66A 3w2tB-4wjlA:
41.1		 3w2tB-4wjlA:
36.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.50A 3w2tB-4wjlA:
41.1		 3w2tB-4wjlA:
36.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 6 GLN A 191
ASP A 247
GLU A 350
LEU A 251
 None
 1.15A 4ax8A-4wjlA:
undetectable		 4ax8A-4wjlA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 TYR A 652
GLY A 654
ALA A 657
SER A 706
GLU A 570
 None
 1.48A 4bupB-4wjlA:
undetectable		 4bupB-4wjlA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 GLN A 341
TRP A 367
ASN A 342
THR A 363
 None
None
NAG  A 807 (-1.8A)
NAG  A 807 ( 4.9A)
 1.09A 4d1yA-4wjlA:
undetectable
4d1yB-4wjlA:
undetectable		 4d1yA-4wjlA:
14.06
4d1yB-4wjlA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 5 SER A 446
GLY A 449
VAL A 576
ASP A 578
 None
 0.94A 4eohA-4wjlA:
undetectable		 4eohA-4wjlA:
18.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 233
GLU A 234
TYR A 683
VAL A 730
HIS A 759
 None
 0.72A 4ffwA-4wjlA:
40.5		 4ffwA-4wjlA:
38.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 233
GLU A 234
TYR A 683
VAL A 730
HIS A 759
 None
 0.63A 4ffwB-4wjlA:
40.3		 4ffwB-4wjlA:
38.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 ALA A 657
PHE A 668
LEU A 645
GLY A 601
LEU A 547
 None
 1.11A 4kykA-4wjlA:
2.9
4kykB-4wjlA:
2.9		 4kykA-4wjlA:
13.80
4kykB-4wjlA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L64_A_C2FA802_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 7 LYS A 529
SER A  70
ARG A  68
VAL A 587
 None
 1.34A 4l64A-4wjlA:
undetectable		 4l64A-4wjlA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 5 TYR A 320
ARG A 339
GLU A 234
VAL A 730
 None
 1.40A 4nkvB-4wjlA:
undetectable		 4nkvB-4wjlA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 11 HIS A 741
LEU A 742
ALA A 745
VAL A 707
LEU A 708
 None
 0.74A 4p65C-4wjlA:
undetectable
4p65D-4wjlA:
undetectable
4p65J-4wjlA:
undetectable
4p65L-4wjlA:
undetectable		 4p65C-4wjlA:
2.79
4p65D-4wjlA:
3.60
4p65J-4wjlA:
3.60
4p65L-4wjlA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 5 GLY A 651
GLU A 233
HIS A 150
ASP A 727
 None
 1.18A 5c0oH-4wjlA:
undetectable		 5c0oH-4wjlA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		3 / 3 TRP A 326
ARG A 250
LEU A 308
 None
 0.94A 5dbyA-4wjlA:
undetectable		 5dbyA-4wjlA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 ILE A 656
GLY A 653
ASP A 664
GLU A 665
PHE A 668
 None
 1.37A 5igwA-4wjlA:
2.9		 5igwA-4wjlA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 7 HIS A 581
LEU A 575
VAL A 596
SER A 550
 None
 0.92A 5m8rA-4wjlA:
undetectable		 5m8rA-4wjlA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 HIS A 581
LEU A 575
VAL A 596
SER A 550
 None
 0.96A 5m8rB-4wjlA:
undetectable		 5m8rB-4wjlA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 HIS A 581
LEU A 575
VAL A 596
SER A 550
 None
 0.93A 5m8rC-4wjlA:
undetectable		 5m8rC-4wjlA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 HIS A 581
LEU A 575
VAL A 596
SER A 550
 None
 0.97A 5m8rD-4wjlA:
undetectable		 5m8rD-4wjlA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		3 / 3 LEU A 563
LEU A 564
TRP A 584
 None
 0.92A 5nwuA-4wjlA:
undetectable		 5nwuA-4wjlA:
5.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 8 GLN A 451
GLY A 449
GLU A 494
ILE A 426
 None
 0.92A 5vlmD-4wjlA:
undetectable		 5vlmD-4wjlA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		3 / 3 TYR A 767
LEU A 774
ASP A 585
 None
 0.82A 5zv2B-4wjlA:
undetectable		 5zv2B-4wjlA:
8.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 233
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.67A 6b1eB-4wjlA:
41.1		 6b1eB-4wjlA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		5 / 12 GLU A 234
TYR A 652
TYR A 683
VAL A 730
HIS A 759
 None
 0.50A 6b1eB-4wjlA:
41.1		 6b1eB-4wjlA:
36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA814_0
(UNCHARACTERIZED
PROTEIN)		 4wjl INACTIVE DIPEPTIDYL
PEPTIDASE 10
(Homo
sapiens) 		4 / 5 GLN A 371
ASN A 372
THR A 322
LEU A 236
 None
 1.42A 6d8pA-4wjlA:
undetectable		 6d8pA-4wjlA:
22.73