SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wjm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AO8_A_MTXA170_1
(DIHYDROFOLATE
REDUCTASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ALA A 298
ASP A 249
THR A  64
SER A  68
ALA A  28
 None
ANP  A 401 ( 4.3A)
None
None
None
 1.10A 1ao8A-4wjmA:
undetectable		 1ao8A-4wjmA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.47A 1bx4A-4wjmA:
29.2		 1bx4A-4wjmA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.94A 1bx4A-4wjmA:
29.2		 1bx4A-4wjmA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 THR A 217
GLY A 219
ALA A 247
GLY A 248
ALA A 289
 ANP  A 401 (-3.5A)
ANP  A 401 (-3.6A)
ANP  A 401 (-3.3A)
ANP  A 401 (-3.4A)
ANP  A 401 (-3.5A)
 0.45A 1bx4A-4wjmA:
29.2		 1bx4A-4wjmA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 8 GLY A  58
ALA A   8
THR A  82
ILE A  52
 None
 0.79A 1c9sI-4wjmA:
undetectable
1c9sJ-4wjmA:
undetectable		 1c9sI-4wjmA:
13.11
1c9sJ-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 1c9sN-4wjmA:
undetectable
1c9sO-4wjmA:
undetectable		 1c9sN-4wjmA:
13.11
1c9sO-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 11 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 1c9sP-4wjmA:
undetectable
1c9sQ-4wjmA:
undetectable		 1c9sP-4wjmA:
13.11
1c9sQ-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 9 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.09A 1gtfO-4wjmA:
undetectable
1gtfP-4wjmA:
undetectable		 1gtfO-4wjmA:
13.11
1gtfP-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.09A 1gtfL-4wjmA:
undetectable
1gtfV-4wjmA:
undetectable		 1gtfL-4wjmA:
13.11
1gtfV-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 7 GLY A  58
ALA A   8
THR A  82
ILE A  52
 None
 0.82A 1gtnA-4wjmA:
undetectable
1gtnK-4wjmA:
undetectable		 1gtnA-4wjmA:
13.11
1gtnK-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 8 GLY A  58
ALA A   8
THR A  82
ILE A  52
 None
 0.79A 1gtnE-4wjmA:
undetectable
1gtnF-4wjmA:
undetectable		 1gtnE-4wjmA:
13.11
1gtnF-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 9 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.09A 1gtnS-4wjmA:
undetectable
1gtnT-4wjmA:
undetectable		 1gtnS-4wjmA:
13.11
1gtnT-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.08A 1gtnU-4wjmA:
undetectable
1gtnV-4wjmA:
undetectable		 1gtnU-4wjmA:
13.11
1gtnV-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.57A 1liiA-4wjmA:
27.3		 1liiA-4wjmA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.89A 1liiA-4wjmA:
27.3		 1liiA-4wjmA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.60A 1likA-4wjmA:
28.7		 1likA-4wjmA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.93A 1likA-4wjmA:
28.7		 1likA-4wjmA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 THR A 217
GLY A 219
HIS A 221
ALA A 247
ALA A 289
 ANP  A 401 (-3.5A)
ANP  A 401 (-3.6A)
None
ANP  A 401 (-3.3A)
ANP  A 401 (-3.5A)
 0.88A 1likA-4wjmA:
28.7		 1likA-4wjmA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 6 LEU A 154
GLY A 126
ILE A 158
HIS A 169
 None
 0.93A 1yajF-4wjmA:
undetectable		 1yajF-4wjmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ALA A  85
 None
 0.64A 2c49A-4wjmA:
29.5		 2c49A-4wjmA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.46A 2c49A-4wjmA:
29.5		 2c49A-4wjmA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 7 ASP A  11
GLY A  29
GLY A  30
ASN A  34
PHE A  98
 None
 0.63A 2c49B-4wjmA:
31.3		 2c49B-4wjmA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 THR A 244
GLY A 248
THR A 250
ALA A 289
VAL A 241
 ANP  A 401 (-4.3A)
ANP  A 401 (-3.4A)
None
ANP  A 401 (-3.5A)
ANP  A 401 (-4.9A)
 1.37A 2coiA-4wjmA:
undetectable
2coiB-4wjmA:
undetectable		 2coiA-4wjmA:
20.20
2coiB-4wjmA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 VAL A 241
THR A 244
GLY A 248
THR A 250
ALA A 289
 ANP  A 401 (-4.9A)
ANP  A 401 (-4.3A)
ANP  A 401 (-3.4A)
None
ANP  A 401 (-3.5A)
 1.36A 2coiA-4wjmA:
undetectable
2coiB-4wjmA:
undetectable		 2coiA-4wjmA:
20.20
2coiB-4wjmA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 11 THR A 244
GLY A 248
THR A 250
ALA A 289
VAL A 241
 ANP  A 401 (-4.3A)
ANP  A 401 (-3.4A)
None
ANP  A 401 (-3.5A)
ANP  A 401 (-4.9A)
 1.38A 2cojA-4wjmA:
undetectable
2cojB-4wjmA:
undetectable		 2cojA-4wjmA:
20.20
2cojB-4wjmA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 9 VAL A 241
THR A 244
GLY A 248
THR A 250
ALA A 289
 ANP  A 401 (-4.9A)
ANP  A 401 (-4.3A)
ANP  A 401 (-3.4A)
None
ANP  A 401 (-3.5A)
 1.35A 2cojA-4wjmA:
undetectable
2cojB-4wjmA:
undetectable		 2cojA-4wjmA:
20.20
2cojB-4wjmA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.62A 2pkkA-4wjmA:
28.0		 2pkkA-4wjmA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.62A 2pkmA-4wjmA:
27.6		 2pkmA-4wjmA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ILE A 255
LEU A  42
VAL A  70
THR A  46
LEU A 124
 None
 1.12A 2qo5A-4wjmA:
undetectable		 2qo5A-4wjmA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 ASP A 249
ILE A  10
PHE A  48
LEU A  39
GLY A   6
 ANP  A 401 ( 4.3A)
None
None
None
None
 1.10A 2v0mA-4wjmA:
undetectable		 2v0mA-4wjmA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		3 / 3 TYR A 139
GLU A   7
THR A  35
 None
 0.93A 2y7hB-4wjmA:
2.7		 2y7hB-4wjmA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A 100
SER A  78
PHE A  57
LEU A  61
TYR A 139
 EDO  A 403 (-3.0A)
None
None
None
None
 1.15A 3cl9A-4wjmA:
undetectable		 3cl9A-4wjmA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 ALA A 289
ILE A 278
THR A 227
THR A 250
ILE A   2
 ANP  A 401 (-3.5A)
None
None
None
None
 1.21A 3prsA-4wjmA:
undetectable		 3prsA-4wjmA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		7 / 12 ASP A  11
GLY A  29
GLY A  30
SER A  31
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.55A 3uboA-4wjmA:
31.1		 3uboA-4wjmA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.26A 3uboB-4wjmA:
31.5		 3uboB-4wjmA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.62A 3uq6A-4wjmA:
30.1		 3uq6A-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.94A 3uq6A-4wjmA:
30.1		 3uq6A-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.58A 3uq6B-4wjmA:
29.6		 3uq6B-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.63A 3vaqA-4wjmA:
29.9		 3vaqA-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.90A 3vaqA-4wjmA:
29.9		 3vaqA-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.55A 3vaqB-4wjmA:
29.2		 3vaqB-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.91A 3vaqB-4wjmA:
29.2		 3vaqB-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.57A 3vasA-4wjmA:
30.0		 3vasA-4wjmA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.89A 3vasA-4wjmA:
30.0		 3vasA-4wjmA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.48A 3vasB-4wjmA:
22.7		 3vasB-4wjmA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.86A 3vasB-4wjmA:
22.7		 3vasB-4wjmA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
ASN A  34
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.54A 4dc3A-4wjmA:
29.1		 4dc3A-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
ASN A  34
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.95A 4dc3A-4wjmA:
29.1		 4dc3A-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.60A 4dc3B-4wjmA:
30.0		 4dc3B-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.92A 4dc3B-4wjmA:
30.0		 4dc3B-4wjmA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.27A 4e3aA-4wjmA:
31.4		 4e3aA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.57A 4e3aB-4wjmA:
31.2		 4e3aB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.27A 4e3aB-4wjmA:
31.2		 4e3aB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.51A 4jksA-4wjmA:
31.5		 4jksA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.50A 4jksB-4wjmA:
31.6		 4jksB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.49A 4jkuA-4wjmA:
30.5		 4jkuA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.25A 4jkuB-4wjmA:
31.6		 4jkuB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.51A 4k8cA-4wjmA:
30.4		 4k8cA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.51A 4k8cB-4wjmA:
31.5		 4k8cB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.52A 4k8kA-4wjmA:
31.4		 4k8kA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.50A 4k8kB-4wjmA:
31.5		 4k8kB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.26A 4k8pA-4wjmA:
31.5		 4k8pA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.27A 4k8pB-4wjmA:
31.5		 4k8pB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.27A 4k8tA-4wjmA:
31.5		 4k8tA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.28A 4k8tB-4wjmA:
31.5		 4k8tB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.27A 4k93A-4wjmA:
31.5		 4k93A-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.27A 4k93B-4wjmA:
31.6		 4k93B-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.26A 4k9cA-4wjmA:
31.5		 4k9cA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.25A 4k9cB-4wjmA:
31.5		 4k9cB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.27A 4k9iA-4wjmA:
31.5		 4k9iA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.27A 4k9iB-4wjmA:
31.5		 4k9iB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.27A 4kadA-4wjmA:
31.5		 4kadA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.26A 4kadB-4wjmA:
30.4		 4kadB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.52A 4kahA-4wjmA:
30.4		 4kahA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.52A 4kahB-4wjmA:
31.6		 4kahB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.52A 4kalA-4wjmA:
31.6		 4kalA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.51A 4kalB-4wjmA:
31.5		 4kalB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.50A 4kanA-4wjmA:
30.3		 4kanA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.51A 4kanB-4wjmA:
31.5		 4kanB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.53A 4kbeA-4wjmA:
30.4		 4kbeA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.53A 4kbeB-4wjmA:
30.4		 4kbeB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.51A 4lbgA-4wjmA:
31.4		 4lbgA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.52A 4lbgB-4wjmA:
31.5		 4lbgB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.28A 4lbxA-4wjmA:
31.4		 4lbxA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.28A 4lbxB-4wjmA:
31.5		 4lbxB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.28A 4lc4A-4wjmA:
31.4		 4lc4A-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
LEU A 162
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.28A 4lc4B-4wjmA:
31.4		 4lc4B-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.52A 4lcaA-4wjmA:
31.5		 4lcaA-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.50A 4lcaB-4wjmA:
31.5		 4lcaB-4wjmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.50A 4n09A-4wjmA:
29.9		 4n09A-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 GLY A  30
ASN A  34
ALA A  85
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.98A 4n09A-4wjmA:
29.9		 4n09A-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A  42
ASN A 157
ALA A  38
GLY A 126
ASP A 155
 None
ANP  A 401 (-3.6A)
None
None
None
 1.11A 4n09A-4wjmA:
29.9		 4n09A-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.53A 4n09B-4wjmA:
30.0		 4n09B-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 CYH A 127
ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.32A 4n09B-4wjmA:
30.0		 4n09B-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 GLY A  30
ASN A  34
ALA A  85
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 1.00A 4n09B-4wjmA:
30.0		 4n09B-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.92A 4n09B-4wjmA:
30.0		 4n09B-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.53A 4n09C-4wjmA:
29.9		 4n09C-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 CYH A 127
ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
None
ANP  A 401 ( 4.3A)
 1.32A 4n09C-4wjmA:
29.9		 4n09C-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.95A 4n09C-4wjmA:
29.9		 4n09C-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		6 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.52A 4n09D-4wjmA:
29.9		 4n09D-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 GLY A  30
ASN A  34
ALA A  85
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.99A 4n09D-4wjmA:
29.9		 4n09D-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.93A 4n09D-4wjmA:
29.9		 4n09D-4wjmA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_B_SAMB603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 9 LEU A 256
ASP A 155
VAL A 251
THR A 217
ILE A 216
 None
None
None
ANP  A 401 (-3.5A)
None
 1.49A 4pcuA-4wjmA:
2.6
4pcuB-4wjmA:
2.4		 4pcuA-4wjmA:
21.48
4pcuB-4wjmA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 7 ALA A  36
THR A  35
ALA A 253
THR A  46
 None
 1.03A 4qw0K-4wjmA:
undetectable		 4qw0K-4wjmA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 7 ALA A  36
THR A  35
ALA A 253
THR A  46
 None
 1.03A 4qw0Y-4wjmA:
undetectable		 4qw0Y-4wjmA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
THR A  35
THR A 250
ALA A 247
ASN A 157
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 (-3.6A)
 1.42A 4u15B-4wjmA:
undetectable		 4u15B-4wjmA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 ASP A  11
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.50A 4ubeA-4wjmA:
27.9		 4ubeA-4wjmA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 9 ALA A 122
GLN A 277
LEU A 273
LEU A 265
LEU A 270
 None
 1.37A 4x30A-4wjmA:
undetectable		 4x30A-4wjmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		3 / 3 ASP A  11
ARG A  67
ARG A  41
 None
 0.95A 4x5iA-4wjmA:
undetectable		 4x5iA-4wjmA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 ARG A 287
ALA A 288
LEU A  42
ALA A 303
ALA A 257
 EDO  A 404 (-3.6A)
None
None
None
None
 1.12A 4zbrA-4wjmA:
undetectable		 4zbrA-4wjmA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5eeuP-4wjmA:
undetectable
5eeuQ-4wjmA:
undetectable		 5eeuP-4wjmA:
13.11
5eeuQ-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5eevP-4wjmA:
undetectable
5eevQ-4wjmA:
undetectable		 5eevP-4wjmA:
13.11
5eevQ-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5eewP-4wjmA:
undetectable
5eewQ-4wjmA:
undetectable		 5eewP-4wjmA:
13.11
5eewQ-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5eexP-4wjmA:
undetectable
5eexQ-4wjmA:
undetectable		 5eexP-4wjmA:
13.11
5eexQ-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5eeyP-4wjmA:
undetectable
5eeyQ-4wjmA:
undetectable		 5eeyP-4wjmA:
13.11
5eeyQ-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5eezP-4wjmA:
undetectable
5eezQ-4wjmA:
undetectable		 5eezP-4wjmA:
13.11
5eezQ-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5ef0P-4wjmA:
undetectable
5ef0Q-4wjmA:
undetectable		 5ef0P-4wjmA:
13.11
5ef0Q-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5ef1P-4wjmA:
undetectable
5ef1Q-4wjmA:
undetectable		 5ef1P-4wjmA:
13.11
5ef1Q-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5ef2P-4wjmA:
undetectable
5ef2Q-4wjmA:
undetectable		 5ef2P-4wjmA:
13.11
5ef2Q-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 GLY A  58
ALA A   8
THR A  83
THR A  82
ILE A  52
 None
None
EDO  A 403 (-4.1A)
None
None
 1.10A 5ef3P-4wjmA:
undetectable
5ef3Q-4wjmA:
undetectable		 5ef3P-4wjmA:
13.11
5ef3Q-4wjmA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 8 LEU A  65
LEU A   3
ALA A  75
SER A  50
 None
 0.79A 5f1aA-4wjmA:
undetectable		 5f1aA-4wjmA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 GLY A  29
GLY A  30
ASN A  34
GLY A 246
ASP A 249
 None
None
None
ANP  A 401 (-3.3A)
ANP  A 401 ( 4.3A)
 0.50A 5kb5A-4wjmA:
29.4		 5kb5A-4wjmA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 LEU A 162
GLY A  29
GLY A  30
ASN A  34
ASP A 249
 None
None
None
None
ANP  A 401 ( 4.3A)
 0.95A 5kb5A-4wjmA:
29.4		 5kb5A-4wjmA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 THR A 217
GLY A 219
ALA A 247
GLY A 248
ALA A 289
 ANP  A 401 (-3.5A)
ANP  A 401 (-3.6A)
ANP  A 401 (-3.3A)
ANP  A 401 (-3.4A)
ANP  A 401 (-3.5A)
 0.28A 5kb6A-4wjmA:
28.8		 5kb6A-4wjmA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 12 THR A 217
GLY A 219
ALA A 247
GLY A 248
ALA A 289
 ANP  A 401 (-3.5A)
ANP  A 401 (-3.6A)
ANP  A 401 (-3.3A)
ANP  A 401 (-3.4A)
ANP  A 401 (-3.5A)
 0.27A 5kb6B-4wjmA:
28.9		 5kb6B-4wjmA:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 6 LEU A  61
GLY A  58
PHE A  57
TYR A  72
 None
 0.88A 5nooC-4wjmA:
undetectable		 5nooC-4wjmA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 9 PRO A 300
GLY A 248
GLY A 246
LEU A  42
ALA A 253
 None
ANP  A 401 (-3.4A)
ANP  A 401 (-3.3A)
None
None
 1.01A 5o96A-4wjmA:
2.7
5o96B-4wjmA:
2.9		 5o96A-4wjmA:
25.49
5o96B-4wjmA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		5 / 10 PRO A 300
GLY A 248
GLY A 246
LEU A  42
ALA A 253
 None
ANP  A 401 (-3.4A)
ANP  A 401 (-3.3A)
None
None
 1.00A 5o96G-4wjmA:
3.2
5o96H-4wjmA:
3.8		 5o96G-4wjmA:
25.49
5o96H-4wjmA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 5 ASN A 157
ASP A 249
ASN A  34
ASP A  11
 ANP  A 401 (-3.6A)
ANP  A 401 ( 4.3A)
None
None
 1.11A 5vooA-4wjmA:
2.3		 5vooA-4wjmA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		4 / 5 ASN A 157
ASP A 249
ASN A  34
ASP A  11
 ANP  A 401 (-3.6A)
ANP  A 401 ( 4.3A)
None
None
 1.12A 5vooC-4wjmA:
2.4		 5vooC-4wjmA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		3 / 3 ILE A 128
ASN A  34
CYH A   4
 None
 0.85A 6bp4A-4wjmA:
undetectable		 6bp4A-4wjmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB
(Brucella
abortus) 		3 / 3 HIS A 229
ASN A 228
LEU A 207
 None
 0.78A 6f7lB-4wjmA:
3.8		 6f7lB-4wjmA:
22.52