SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wkz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 4wkz AUTONOMOUS COHESIN
(Ruminococcus
flavefaciens) 		4 / 7 ALA B  95
GLY B 134
PHE B 168
PHE B 182
 None
 0.97A 2wq5A-4wkzB:
undetectable		 2wq5A-4wkzB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 4wkz AUTONOMOUS COHESIN
(Ruminococcus
flavefaciens) 		5 / 10 GLY B 188
GLY B 159
LEU B 158
LEU B  76
TYR B 156
 None
 1.33A 5hwkA-4wkzB:
undetectable		 5hwkA-4wkzB:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 4wkz AUTONOMOUS COHESIN
(Ruminococcus
flavefaciens) 		5 / 10 GLY B 188
GLY B 159
LEU B 158
LEU B  76
TYR B 156
 None
 1.33A 5hwkB-4wkzB:
undetectable		 5hwkB-4wkzB:
22.31