SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wli'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUD_D_SUED1201_1 (NS3 PROTEASE, NS4A PROTEIN)	4wli	YUIC (Bacillus subtilis)	5 / 12	GLY A 115 ALA A 150 ALA A 127 ALA A 128 ASP A 162	None None EDO A 301 (-3.5A) None EDO A 301 (-3.5A)	1.03A	3sudD-4wliA: undetectable	3sudD-4wliA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACB_C_DXCC1477_0 (TRANSLATION ELONGATION FACTOR SELB)	4wli	YUIC (Bacillus subtilis)	4 / 6	THR A 125 GLY A 147 ARG A 160 ILE A 141	None	0.84A	4acbC-4wliA: undetectable	4acbC-4wliA: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_A_SAMA801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	4wli	YUIC (Bacillus subtilis)	5 / 12	ILE A 156 GLY A 153 ALA A 127 TYR A 93 LEU A 161	None EDO A 301 (-3.6A) EDO A 301 (-3.5A) EDO A 301 (-3.6A) None	1.14A	5hw4A-4wliA: undetectable	5hw4A-4wliA: 22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_B_SAMB801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	4wli	YUIC (Bacillus subtilis)	5 / 11	ILE A 156 GLY A 153 ALA A 127 TYR A 93 LEU A 161	None EDO A 301 (-3.6A) EDO A 301 (-3.5A) EDO A 301 (-3.6A) None	1.16A	5hw4B-4wliA: undetectable	5hw4B-4wliA: 22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_C_SAMC801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	4wli	YUIC (Bacillus subtilis)	5 / 12	ILE A 156 GLY A 153 ALA A 127 TYR A 93 LEU A 161	None EDO A 301 (-3.6A) EDO A 301 (-3.5A) EDO A 301 (-3.6A) None	1.13A	5hw4C-4wliA: undetectable	5hw4C-4wliA: 22.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3SUD_D_SUED1201_1","NS3 PROTEASE, NS4A PROTEIN","4wli","YUIC","Bacillus subtilis",5,"GLY A 115;ALA A 150;ALA A 127;ALA A 128;ASP A 162","None;None;EDO A 301 (-3.5A);None;EDO A 301 (-3.5A)","1.03A","3sudD-4wliA:undetectable","3sudD-4wliA:21.13"],["4ACB_C_DXCC1477_0","TRANSLATION ELONGATION FACTOR SELB","4wli","YUIC","Bacillus subtilis",4,"THR A 125;GLY A 147;ARG A 160;ILE A 141","None","0.84A","4acbC-4wliA:undetectable","4acbC-4wliA:17.03"],["5HW4_A_SAMA801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","4wli","YUIC","Bacillus subtilis",5,"ILE A 156;GLY A 153;ALA A 127;TYR A  93;LEU A 161","None;EDO A 301 (-3.6A);EDO A 301 (-3.5A);EDO A 301 (-3.6A);None","1.14A","5hw4A-4wliA:undetectable","5hw4A-4wliA:22.33"],["5HW4_B_SAMB801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","4wli","YUIC","Bacillus subtilis",5,"ILE A 156;GLY A 153;ALA A 127;TYR A  93;LEU A 161","None;EDO A 301 (-3.6A);EDO A 301 (-3.5A);EDO A 301 (-3.6A);None","1.16A","5hw4B-4wliA:undetectable","5hw4B-4wliA:22.33"],["5HW4_C_SAMC801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","4wli","YUIC","Bacillus subtilis",5,"ILE A 156;GLY A 153;ALA A 127;TYR A  93;LEU A 161","None;EDO A 301 (-3.6A);EDO A 301 (-3.5A);EDO A 301 (-3.6A);None","1.13A","5hw4C-4wliA:undetectable","5hw4C-4wliA:22.33"]]