SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4wmy INTELECTIN-1
(Homo
sapiens) 		3 / 3 TRP A 161
VAL A 308
TRP A 150
 None
 1.12A 1c4dA-4wmyA:
undetectable
1c4dB-4wmyA:
undetectable		 1c4dA-4wmyA:
4.59
1c4dB-4wmyA:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 4wmy INTELECTIN-1
(Homo
sapiens) 		5 / 10 TRP A 117
LEU A 147
LEU A 183
TYR A 187
ALA A 252
 None
 1.40A 1pbcA-4wmyA:
undetectable		 1pbcA-4wmyA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 4wmy INTELECTIN-1
(Homo
sapiens) 		5 / 10 VAL A 236
TRP A 117
LEU A 147
LEU A 183
TYR A 187
 None
 1.25A 1pbcA-4wmyA:
undetectable		 1pbcA-4wmyA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4wmy INTELECTIN-1
(Homo
sapiens) 		5 / 10 ILE A 149
GLY A 148
THR A 171
LEU A 183
PHE A 238
 None
 1.14A 1z11C-4wmyA:
undetectable		 1z11C-4wmyA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4wmy INTELECTIN-1
(Homo
sapiens) 		5 / 10 ILE A 149
GLY A 148
THR A 171
LEU A 183
PHE A 238
 None
 1.07A 1z11D-4wmyA:
undetectable		 1z11D-4wmyA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 4wmy INTELECTIN-1
(Homo
sapiens) 		5 / 10 ILE A 149
ALA A 252
VAL A 209
ILE A 207
VAL A 206
 None
 1.06A 2nnjA-4wmyA:
undetectable		 2nnjA-4wmyA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 4wmy INTELECTIN-1
(Homo
sapiens) 		5 / 10 TYR A 187
PHE A 238
VAL A 206
ILE A 266
ASN A 248
 None
 1.11A 3km6A-4wmyA:
undetectable		 3km6A-4wmyA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 4wmy INTELECTIN-1
(Homo
sapiens) 		4 / 8 GLY A 174
PHE A 175
ILE A 142
PHE A 238
 None
 0.78A 3ko0O-4wmyA:
undetectable
3ko0Q-4wmyA:
undetectable		 3ko0O-4wmyA:
16.22
3ko0Q-4wmyA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4wmy INTELECTIN-1
(Homo
sapiens) 		4 / 8 GLU A  87
HIS A  86
ASN A  88
LYS A 155
 CA  A 402 (-2.9A)
None
None
None
 1.22A 3kp6A-4wmyA:
undetectable
3kp6B-4wmyA:
undetectable		 3kp6A-4wmyA:
19.09
3kp6B-4wmyA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 4wmy INTELECTIN-1
(Homo
sapiens) 		3 / 3 ASP A  71
SER A  74
ARG A 168
 None
 0.92A 3loqA-4wmyA:
undetectable		 3loqA-4wmyA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 4wmy INTELECTIN-1
(Homo
sapiens) 		5 / 11 ILE A 149
GLY A 148
THR A 171
LEU A 183
PHE A 238
 None
 0.94A 3t3rA-4wmyA:
undetectable		 3t3rA-4wmyA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 4wmy INTELECTIN-1
(Homo
sapiens) 		5 / 12 GLN A 278
GLY A 290
ASP A 287
PHE A 286
SER A 299
 None
 1.25A 3t7sD-4wmyA:
undetectable		 3t7sD-4wmyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 4wmy INTELECTIN-1
(Homo
sapiens) 		3 / 3 ARG A 245
PRO A 191
PHE A 241
 None
 1.04A 3thrC-4wmyA:
undetectable		 3thrC-4wmyA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4wmy INTELECTIN-1
(Homo
sapiens) 		3 / 3 HIS A 263
GLU A 230
ASN A 243
 3S6  A 404 (-3.8A)
None
None
 0.99A 4bupB-4wmyA:
undetectable		 4bupB-4wmyA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 4wmy INTELECTIN-1
(Homo
sapiens) 		3 / 3 GLU A  87
ASP A  89
ASP A 132
 CA  A 402 (-2.9A)
None
None
 0.60A 4gc9A-4wmyA:
undetectable		 4gc9A-4wmyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4wmy INTELECTIN-1
(Homo
sapiens) 		3 / 3 ASN A  88
ASP A 133
ASP A 114
 None
CA  A 401 (-2.1A)
None
 0.78A 4obwD-4wmyA:
undetectable		 4obwD-4wmyA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 4wmy INTELECTIN-1
(Homo
sapiens) 		3 / 3 ARG A  99
ASP A 133
TRP A 100
 None
CA  A 401 (-2.1A)
None
 1.11A 4xdqA-4wmyA:
undetectable		 4xdqA-4wmyA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 4wmy INTELECTIN-1
(Homo
sapiens) 		4 / 6 ASN A 116
TRP A 117
ARG A 239
GLY A 269
 None
 1.12A 5o4yA-4wmyA:
undetectable		 5o4yA-4wmyA:
4.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 4wmy INTELECTIN-1
(Homo
sapiens) 		5 / 10 VAL A 256
GLY A 258
GLU A 230
ASN A 242
ASN A 248
 None
 1.05A 5x6yB-4wmyA:
undetectable		 5x6yB-4wmyA:
15.87