SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wny'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4wny UNIVERSAL STRESS
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 ALA A   8
ARG A  85
ALA A 103
ARG A  99
 None
 1.03A 3twpA-4wnyA:
2.5		 3twpA-4wnyA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4wny UNIVERSAL STRESS
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 ALA A   8
ARG A  85
ALA A 103
ARG A  99
 None
 0.97A 3twpB-4wnyA:
2.3		 3twpB-4wnyA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 4wny UNIVERSAL STRESS
PROTEIN
(Burkholderia
pseudomallei) 		3 / 3 ILE A   5
MET A  75
ARG A  74
 None
 0.87A 4lnwA-4wnyA:
undetectable		 4lnwA-4wnyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 4wny UNIVERSAL STRESS
PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 ASP A  20
VAL A   7
ALA A   8
VAL A  67
SER A  16
 None
 1.32A 4mm6A-4wnyA:
undetectable		 4mm6A-4wnyA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4wny UNIVERSAL STRESS
PROTEIN
(Burkholderia
pseudomallei) 		5 / 7 SER A  16
ASP A  69
ARG A  65
GLY A  64
GLU A  62
 None
 1.37A 5btaA-4wnyA:
undetectable
5btaC-4wnyA:
undetectable
5btaD-4wnyA:
2.2		 5btaA-4wnyA:
16.99
5btaC-4wnyA:
16.99
5btaD-4wnyA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4wny UNIVERSAL STRESS
PROTEIN
(Burkholderia
pseudomallei) 		5 / 7 SER A  16
ASP A  69
ARG A  65
GLY A  64
GLU A  62
 None
 1.44A 5btfA-4wnyA:
undetectable
5btfB-4wnyA:
2.6
5btfC-4wnyA:
undetectable		 5btfA-4wnyA:
16.99
5btfB-4wnyA:
20.97
5btfC-4wnyA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4wny UNIVERSAL STRESS
PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 SER A  16
ASP A  69
GLY A  64
GLU A  62
 None
 1.11A 5btfA-4wnyA:
undetectable
5btfC-4wnyA:
undetectable
5btfD-4wnyA:
2.2		 5btfA-4wnyA:
16.99
5btfC-4wnyA:
16.99
5btfD-4wnyA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 4wny UNIVERSAL STRESS
PROTEIN
(Burkholderia
pseudomallei) 		5 / 10 LEU A  68
ALA A  71
LEU A   9
ILE A   5
LEU A  23
 None
 1.36A 6cbzB-4wnyA:
undetectable		 6cbzB-4wnyA:
20.59