SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4woy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		5 / 12 LEU A 176
LEU A 196
VAL A 303
LEU A 258
ALA A 261
 None
 0.92A 1gseB-4woyA:
undetectable		 1gseB-4woyA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 5 ARG A 195
LEU A 331
ASP A 333
LEU A 334
 None
 1.15A 1n13B-4woyA:
undetectable
1n13C-4woyA:
undetectable		 1n13B-4woyA:
16.46
1n13C-4woyA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		5 / 10 LEU A 197
VAL A 194
TYR A 335
PRO A 321
LEU A 318
 None
 1.48A 1sv5A-4woyA:
undetectable		 1sv5A-4woyA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 5 LEU A 288
ILE A 279
ILE A 156
ALA A 157
 None
 0.67A 2i2zA-4woyA:
2.6		 2i2zA-4woyA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 5 LEU A 288
ALA A 302
TRP A 320
LEU A 304
 None
 1.12A 2oaxA-4woyA:
undetectable		 2oaxA-4woyA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 6 ASP A 437
TYR A 441
PHE A 431
LEU A 373
 None
 0.92A 2w98A-4woyA:
undetectable
2w98B-4woyA:
undetectable		 2w98A-4woyA:
20.47
2w98B-4woyA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		5 / 12 PHE A 173
LEU A 171
GLU A 170
ALA A 261
SER A 265
 None
 1.47A 3apvA-4woyA:
undetectable		 3apvA-4woyA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 8 PHE A 454
GLU A 451
PHE A 401
LEU A 402
 None
 1.01A 3i45A-4woyA:
undetectable		 3i45A-4woyA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 6 LEU A 257
PHE A 173
ALA A 198
LEU A 262
 None
 0.98A 3t3zA-4woyA:
undetectable		 3t3zA-4woyA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 6 LEU A 257
PHE A 173
ALA A 198
LEU A 262
 None
 0.99A 3t3zB-4woyA:
undetectable		 3t3zB-4woyA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 6 LEU A 257
PHE A 173
ALA A 198
LEU A 262
 None
 0.96A 3t3zD-4woyA:
undetectable		 3t3zD-4woyA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 6 LEU A 443
TYR A 441
LEU A 412
GLU A 413
 None
 1.13A 4f3tA-4woyA:
undetectable		 4f3tA-4woyA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 8 ILE A 156
LEU A 152
LEU A 301
ILE A 279
 None
 0.68A 4zvcA-4woyA:
undetectable
4zvcB-4woyA:
undetectable		 4zvcA-4woyA:
15.24
4zvcB-4woyA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 8 ILE A 279
ILE A 156
LEU A 152
LEU A 301
 None
 0.67A 4zvcA-4woyA:
undetectable
4zvcB-4woyA:
undetectable		 4zvcA-4woyA:
15.24
4zvcB-4woyA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 5 SER A 238
ARG A 226
GLY A 247
THR A 215
 None
 1.13A 5btiA-4woyA:
undetectable
5btiB-4woyA:
undetectable		 5btiA-4woyA:
22.53
5btiB-4woyA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 5 SER A 238
ARG A 226
GLY A 247
THR A 215
 None
 1.13A 5btiC-4woyA:
undetectable
5btiD-4woyA:
undetectable		 5btiC-4woyA:
22.53
5btiD-4woyA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		4 / 5 LEU A 443
TYR A 441
LEU A 412
GLU A 413
 None
 1.22A 5weaA-4woyA:
2.1		 5weaA-4woyA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		3 / 3 ARG A 353
ARG A 354
ASP A 346
 None
 0.90A 6d8pA-4woyA:
undetectable		 6d8pA-4woyA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 4woy MITOCHONDRIAL
DYNAMICS PROTEIN
MID49
(Mus
musculus) 		5 / 10 ALA A 261
LEU A 262
VAL A 266
ALA A 157
ALA A 198
 None
 0.85A 6h1lA-4woyA:
undetectable		 6h1lA-4woyA:
22.70