SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wp8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4wp8 MA1120
(Mycobacterium
avium) 		5 / 10 ILE A 146
ILE A 144
VAL A 142
GLY A 106
VAL A  92
 None
 1.17A 3elzC-4wp8A:
undetectable		 3elzC-4wp8A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 4wp8 MA1120
(Mycobacterium
avium) 		4 / 8 SER A  65
ASP A 105
ASN A  69
SER A 102
 ZDA  A 303 (-3.0A)
MN  A 301 ( 2.7A)
None
None
 1.13A 5l1fA-4wp8A:
undetectable
5l1fB-4wp8A:
undetectable		 5l1fA-4wp8A:
13.40
5l1fB-4wp8A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 4wp8 MA1120
(Mycobacterium
avium) 		5 / 12 ILE A 194
PHE A 196
ALA A 187
ASP A 186
ILE A 146
 None
 1.06A 6dwnD-4wp8A:
undetectable		 6dwnD-4wp8A:
20.36