SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wpm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4wpm MRNA EXPORT PROTEIN
(Chaetomium
thermophilum) 		5 / 11 LEU A 123
LEU A 136
ILE A 140
PRO A 181
LEU A 171
 None
 1.35A 2ft9A-4wpmA:
undetectable		 2ft9A-4wpmA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 4wpm MRNA EXPORT PROTEIN
(Chaetomium
thermophilum) 		3 / 3 LEU A 161
ARG A 160
ILE A 173
 None
SO4  A 303 ( 3.5A)
None
 0.64A 2xn5B-4wpmA:
undetectable		 2xn5B-4wpmA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 4wpm MRNA EXPORT PROTEIN
(Chaetomium
thermophilum) 		5 / 12 LEU A 136
SER A 121
LEU A 158
GLY A 105
LEU A 171
 None
 0.98A 6b0cD-4wpmA:
undetectable		 6b0cD-4wpmA:
21.55