SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wpx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICT_C_T44C128_1 (TRANSTHYRETIN)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	LEU A 43 ALA A 96 LEU A 55 GLU A 30 LEU A 52	None	1.15A	1ictA-4wpxA: undetectable 1ictC-4wpxA: undetectable	1ictA-4wpxA: 18.44 1ictC-4wpxA: 18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LXF_C_BEPC92_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	7 / 12	PHE A 120 ILE A 128 LEU A 133 MET A 152 ILE A 153 VAL A 164 MET A 173	None	0.93A	1lxfC-4wpxA: 7.7	1lxfC-4wpxA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y69_C_CHDC1265_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.01A	2y69C-4wpxA: undetectable 2y69J-4wpxA: undetectable	2y69C-4wpxA: 21.84 2y69J-4wpxA: 17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y69_P_CHDP1265_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.99A	2y69P-4wpxA: undetectable 2y69W-4wpxA: undetectable	2y69P-4wpxA: 21.84 2y69W-4wpxA: 17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.99A	3abkP-4wpxA: undetectable 3abkW-4wpxA: undetectable	3abkP-4wpxA: 21.84 3abkW-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.02A	3ablP-4wpxA: undetectable 3ablW-4wpxA: undetectable	3ablP-4wpxA: 21.84 3ablW-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.97A	3abmC-4wpxA: undetectable 3abmJ-4wpxA: undetectable	3abmC-4wpxA: 21.84 3abmJ-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_P_CHDP1271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.01A	3abmP-4wpxA: undetectable 3abmW-4wpxA: undetectable	3abmP-4wpxA: 21.84 3abmW-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_C_CHDC271_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.04A	3ag2C-4wpxA: undetectable	3ag2C-4wpxA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.00A	3ag3C-4wpxA: undetectable 3ag3J-4wpxA: undetectable	3ag3C-4wpxA: 21.84 3ag3J-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_P_CHDP1271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.01A	3asnP-4wpxA: undetectable 3asnW-4wpxA: undetectable	3asnP-4wpxA: 21.84 3asnW-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_P_CHDP1271_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.02A	3asoP-4wpxA: undetectable 3asoW-4wpxA: undetectable	3asoP-4wpxA: 21.84 3asoW-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB152_0 (ILEAL BILE ACID-BINDING PROTEIN)	4wpx	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	3 / 3	ASN C 66 HIS C 67 VAL C 87	None	0.78A	3elzB-4wpxC: undetectable	3elzB-4wpxC: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	4wpx	PUTATIVE SAC3 FAMILY PROTEIN PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	5 / 12	LEU C 72 VAL B1121 THR B1113 LEU C 138 HIS C 56	None	1.28A	3sp9B-4wpxC: undetectable	3sp9B-4wpxC: 24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_C_CHDC305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.00A	3wg7C-4wpxA: undetectable 3wg7J-4wpxA: undetectable	3wg7C-4wpxA: 21.84 3wg7J-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.00A	3wg7P-4wpxA: undetectable 3wg7W-4wpxA: undetectable	3wg7P-4wpxA: 21.84 3wg7W-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3X2Q_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.97A	3x2qP-4wpxA: undetectable 3x2qW-4wpxA: undetectable	3x2qP-4wpxA: 21.84 3x2qW-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQT_A_30ZA1920_1 (ANDROGEN RECEPTOR)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	GLY A 101 LEU A 20 ASN A 18 GLU A 15	None	1.01A	3zqtA-4wpxA: undetectable	3zqtA-4wpxA: 19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPN_B_ZMRB700_1 (NEURAMINIDASE)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN PUTATIVE SAC3 FAMILY PROTEIN (Chaetomium thermophilum)	5 / 12	GLU A 112 ARG A 107 ARG A 110 ARG B1160 TYR B1157	None	1.50A	4cpnB-4wpxA: undetectable	4cpnB-4wpxA: 15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_B_SAMB301_1 (PUTATIVE METHYLTRANSFERASE BUD23)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	TYR A 17 GLN A 97 SER A 29 ASP A 22	None	0.96A	4qtuB-4wpxA: undetectable	4qtuB-4wpxA: 23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RJD_A_TFPA203_1 (CALMODULIN)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	5 / 8	PHE A 120 ILE A 128 LEU A 133 MET A 152 VAL A 164	None	0.63A	4rjdA-4wpxA: 12.1	4rjdA-4wpxA: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RJD_B_TFPB203_1 (CALMODULIN)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	PHE A 120 LEU A 133 MET A 152 MET A 173	None	0.78A	4rjdB-4wpxA: 12.2	4rjdB-4wpxA: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RYA_A_MTLA501_1 (ABC TRANSPORTER SUBSTRATE BINDING PROTEIN (SORBITOL))	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN PUTATIVE SAC3 FAMILY PROTEIN (Chaetomium thermophilum; Chaetomium thermophilum)	3 / 3	GLU B1129 TYR A 45 GLU A 46	None	0.82A	4ryaA-4wpxB: undetectable	4ryaA-4wpxB: 11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.02A	5b1bC-4wpxA: undetectable 5b1bJ-4wpxA: undetectable	5b1bC-4wpxA: 21.84 5b1bJ-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1B_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 7	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.99A	5b1bP-4wpxA: undetectable 5b1bW-4wpxA: undetectable	5b1bP-4wpxA: 21.84 5b1bW-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF7_K_6V8K305_0 (PROTEASOME SUBUNIT BETA TYPE-1 PROTEASOME SUBUNIT BETA TYPE-5)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	6 / 11	ALA A 96 THR A 95 ALA A 94 VAL A 51 GLY A 101 ALA A 100	None	1.39A	5lf7K-4wpxA: undetectable 5lf7L-4wpxA: undetectable	5lf7K-4wpxA: 19.35 5lf7L-4wpxA: 23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_I_Z80I401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 9	ILE A 128 PHE A 117 VAL A 136 ASP A 123	None	0.97A	5lg3I-4wpxA: undetectable	5lg3I-4wpxA: 20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.03A	5wauC-4wpxA: undetectable 5wauJ-4wpxA: undetectable	5wauC-4wpxA: 21.84 5wauJ-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_C_CHDC308_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.01A	5wauc-4wpxA: undetectable 5wauj-4wpxA: undetectable	5wauc-4wpxA: 21.84 5wauj-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.09A	5x19P-4wpxA: undetectable	5x19P-4wpxA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.07A	5x1bP-4wpxA: undetectable	5x1bP-4wpxA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDQ_C_CHDC308_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.03A	5xdqC-4wpxA: undetectable 5xdqJ-4wpxA: undetectable	5xdqC-4wpxA: 21.84 5xdqJ-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDQ_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.98A	5xdqP-4wpxA: undetectable 5xdqW-4wpxA: undetectable	5xdqP-4wpxA: 21.84 5xdqW-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.99A	5z84P-4wpxA: undetectable 5z84W-4wpxA: undetectable	5z84P-4wpxA: 21.84 5z84W-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z85_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.00A	5z85P-4wpxA: undetectable 5z85W-4wpxA: undetectable	5z85P-4wpxA: 21.84 5z85W-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.00A	5z86C-4wpxA: undetectable 5z86J-4wpxA: undetectable	5z86C-4wpxA: 21.84 5z86J-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.99A	5z86P-4wpxA: undetectable 5z86W-4wpxA: undetectable	5z86P-4wpxA: 21.84 5z86W-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCO_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	1.00A	5zcoP-4wpxA: undetectable 5zcoW-4wpxA: undetectable	5zcoP-4wpxA: 21.84 5zcoW-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_C_CHDC306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.99A	5zcpC-4wpxA: undetectable 5zcpJ-4wpxA: undetectable	5zcpC-4wpxA: 21.84 5zcpJ-4wpxA: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4wpx	CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	ARG A 27 PHE A 50 PHE A 35 LEU A 34	None	0.99A	5zcpP-4wpxA: undetectable 5zcpW-4wpxA: undetectable	5zcpP-4wpxA: 21.84 5zcpW-4wpxA: 14.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICT_C_T44C128_1","TRANSTHYRETIN;TRANSTHYRETIN","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",5,"LEU A  43;ALA A  96;LEU A  55;GLU A  30;LEU A  52","None","1.15A","1ictA-4wpxA:undetectable;1ictC-4wpxA:undetectable","1ictA-4wpxA:18.44;1ictC-4wpxA:18.44"],["1LXF_C_BEPC92_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",7,"PHE A 120;ILE A 128;LEU A 133;MET A 152;ILE A 153;VAL A 164;MET A 173","None","0.93A","1lxfC-4wpxA:7.7","1lxfC-4wpxA:20.77"],["2Y69_C_CHDC1265_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.01A","2y69C-4wpxA:undetectable;2y69J-4wpxA:undetectable","2y69C-4wpxA:21.84;2y69J-4wpxA:17.22"],["2Y69_P_CHDP1265_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.99A","2y69P-4wpxA:undetectable;2y69W-4wpxA:undetectable","2y69P-4wpxA:21.84;2y69W-4wpxA:17.22"],["3ABK_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.99A","3abkP-4wpxA:undetectable;3abkW-4wpxA:undetectable","3abkP-4wpxA:21.84;3abkW-4wpxA:14.12"],["3ABL_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.02A","3ablP-4wpxA:undetectable;3ablW-4wpxA:undetectable","3ablP-4wpxA:21.84;3ablW-4wpxA:14.12"],["3ABM_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.97A","3abmC-4wpxA:undetectable;3abmJ-4wpxA:undetectable","3abmC-4wpxA:21.84;3abmJ-4wpxA:14.12"],["3ABM_P_CHDP1271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.01A","3abmP-4wpxA:undetectable;3abmW-4wpxA:undetectable","3abmP-4wpxA:21.84;3abmW-4wpxA:14.12"],["3AG2_C_CHDC271_0","CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.04A","3ag2C-4wpxA:undetectable","3ag2C-4wpxA:21.84"],["3AG3_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.00A","3ag3C-4wpxA:undetectable;3ag3J-4wpxA:undetectable","3ag3C-4wpxA:21.84;3ag3J-4wpxA:14.12"],["3ASN_P_CHDP1271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.01A","3asnP-4wpxA:undetectable;3asnW-4wpxA:undetectable","3asnP-4wpxA:21.84;3asnW-4wpxA:14.12"],["3ASO_P_CHDP1271_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.02A","3asoP-4wpxA:undetectable;3asoW-4wpxA:undetectable","3asoP-4wpxA:21.84;3asoW-4wpxA:14.12"],["3ELZ_B_CHDB152_0","ILEAL BILE ACID-BINDING PROTEIN","4wpx","PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",3,"ASN C  66;HIS C  67;VAL C  87","None","0.78A","3elzB-4wpxC:undetectable","3elzB-4wpxC:19.68"],["3SP9_B_IL2B901_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA","4wpx","PUTATIVE SAC3 FAMILY PROTEIN;PUTATIVE UNCHARACTERIZED PROTEIN","Chaetomium thermophilum",5,"LEU C  72;VAL B1121;THR B1113;LEU C 138;HIS C  56","None","1.28A","3sp9B-4wpxC:undetectable","3sp9B-4wpxC:24.04"],["3WG7_C_CHDC305_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.00A","3wg7C-4wpxA:undetectable;3wg7J-4wpxA:undetectable","3wg7C-4wpxA:21.84;3wg7J-4wpxA:14.12"],["3WG7_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.00A","3wg7P-4wpxA:undetectable;3wg7W-4wpxA:undetectable","3wg7P-4wpxA:21.84;3wg7W-4wpxA:14.12"],["3X2Q_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.97A","3x2qP-4wpxA:undetectable;3x2qW-4wpxA:undetectable","3x2qP-4wpxA:21.84;3x2qW-4wpxA:14.12"],["3ZQT_A_30ZA1920_1","ANDROGEN RECEPTOR","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"GLY A 101;LEU A  20;ASN A  18;GLU A  15","None","1.01A","3zqtA-4wpxA:undetectable","3zqtA-4wpxA:19.92"],["4CPN_B_ZMRB700_1","NEURAMINIDASE","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN;PUTATIVE SAC3 FAMILY PROTEIN","Chaetomium thermophilum",5,"GLU A 112;ARG A 107;ARG A 110;ARG B1160;TYR B1157","None","1.50A","4cpnB-4wpxA:undetectable","4cpnB-4wpxA:15.99"],["4QTU_B_SAMB301_1","PUTATIVE METHYLTRANSFERASE BUD23","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"TYR A  17;GLN A  97;SER A  29;ASP A  22","None","0.96A","4qtuB-4wpxA:undetectable","4qtuB-4wpxA:23.94"],["4RJD_A_TFPA203_1","CALMODULIN","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",5,"PHE A 120;ILE A 128;LEU A 133;MET A 152;VAL A 164","None","0.63A","4rjdA-4wpxA:12.1","4rjdA-4wpxA:22.14"],["4RJD_B_TFPB203_1","CALMODULIN","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"PHE A 120;LEU A 133;MET A 152;MET A 173","None","0.78A","4rjdB-4wpxA:12.2","4rjdB-4wpxA:22.14"],["4RYA_A_MTLA501_1","ABC TRANSPORTER SUBSTRATE BINDING PROTEIN (SORBITOL)","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN;PUTATIVE SAC3 FAMILY PROTEIN","Chaetomium thermophilum;Chaetomium thermophilum",3,"GLU B1129;TYR A  45;GLU A  46","None","0.82A","4ryaA-4wpxB:undetectable","4ryaA-4wpxB:11.26"],["5B1B_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.02A","5b1bC-4wpxA:undetectable;5b1bJ-4wpxA:undetectable","5b1bC-4wpxA:21.84;5b1bJ-4wpxA:14.12"],["5B1B_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.99A","5b1bP-4wpxA:undetectable;5b1bW-4wpxA:undetectable","5b1bP-4wpxA:21.84;5b1bW-4wpxA:14.12"],["5LF7_K_6V8K305_0","PROTEASOME SUBUNIT BETA TYPE-1;PROTEASOME SUBUNIT BETA TYPE-5","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",6,"ALA A  96;THR A  95;ALA A  94;VAL A  51;GLY A 101;ALA A 100","None","1.39A","5lf7K-4wpxA:undetectable;5lf7L-4wpxA:undetectable","5lf7K-4wpxA:19.35;5lf7L-4wpxA:23.28"],["5LG3_I_Z80I401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ILE A 128;PHE A 117;VAL A 136;ASP A 123","None","0.97A","5lg3I-4wpxA:undetectable","5lg3I-4wpxA:20.54"],["5WAU_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.03A","5wauC-4wpxA:undetectable;5wauJ-4wpxA:undetectable","5wauC-4wpxA:21.84;5wauJ-4wpxA:14.12"],["5WAU_C_CHDC308_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.01A","5wauc-4wpxA:undetectable;5wauj-4wpxA:undetectable","5wauc-4wpxA:21.84;5wauj-4wpxA:14.12"],["5X19_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.09A","5x19P-4wpxA:undetectable","5x19P-4wpxA:21.84"],["5X1B_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.07A","5x1bP-4wpxA:undetectable","5x1bP-4wpxA:21.84"],["5XDQ_C_CHDC308_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.03A","5xdqC-4wpxA:undetectable;5xdqJ-4wpxA:undetectable","5xdqC-4wpxA:21.84;5xdqJ-4wpxA:14.12"],["5XDQ_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.98A","5xdqP-4wpxA:undetectable;5xdqW-4wpxA:undetectable","5xdqP-4wpxA:21.84;5xdqW-4wpxA:14.12"],["5Z84_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.99A","5z84P-4wpxA:undetectable;5z84W-4wpxA:undetectable","5z84P-4wpxA:21.84;5z84W-4wpxA:14.12"],["5Z85_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.00A","5z85P-4wpxA:undetectable;5z85W-4wpxA:undetectable","5z85P-4wpxA:21.84;5z85W-4wpxA:14.12"],["5Z86_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.00A","5z86C-4wpxA:undetectable;5z86J-4wpxA:undetectable","5z86C-4wpxA:21.84;5z86J-4wpxA:14.12"],["5Z86_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.99A","5z86P-4wpxA:undetectable;5z86W-4wpxA:undetectable","5z86P-4wpxA:21.84;5z86W-4wpxA:14.12"],["5ZCO_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","1.00A","5zcoP-4wpxA:undetectable;5zcoW-4wpxA:undetectable","5zcoP-4wpxA:21.84;5zcoW-4wpxA:14.12"],["5ZCP_C_CHDC306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.99A","5zcpC-4wpxA:undetectable;5zcpJ-4wpxA:undetectable","5zcpC-4wpxA:21.84;5zcpJ-4wpxA:14.12"],["5ZCP_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4wpx","CELL DIVISION CONTROL PROTEIN 31-LIKE PROTEIN","Chaetomium thermophilum",4,"ARG A  27;PHE A  50;PHE A  35;LEU A  34","None","0.99A","5zcpP-4wpxA:undetectable;5zcpW-4wpxA:undetectable","5zcpP-4wpxA:21.84;5zcpW-4wpxA:14.12"]]