SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4wqo VON HIPPEL-LINDAU
DISEASE TUMOR
SUPPRESSOR
(Homo
sapiens) 		6 / 12 PRO A 103
SER A  80
ILE A 151
VAL A  83
LEU A 101
GLY A 106
 None
 1.48A 1uakA-4wqoA:
undetectable		 1uakA-4wqoA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 4wqo CULLIN-2
(Homo
sapiens) 		3 / 3 PRO D   5
GLU D  51
TYR D  49
 None
 0.76A 2zmbA-4wqoD:
undetectable		 2zmbA-4wqoD:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4wqo CULLIN-2
(Homo
sapiens) 		3 / 3 ASN D  67
HIS D  68
VAL D  25
 None
 0.76A 3elzB-4wqoD:
undetectable		 3elzB-4wqoD:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 4wqo VON HIPPEL-LINDAU
DISEASE TUMOR
SUPPRESSOR
(Homo
sapiens) 		4 / 6 ARG A  82
GLN A 164
TYR A 156
LEU A 128
 None
 1.41A 3tgvD-4wqoA:
undetectable		 3tgvD-4wqoA:
17.77