SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wqt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 0.99A 1c8lA-4wqtX:
undetectable		 1c8lA-4wqtX:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 1.02A 1gfzA-4wqtX:
undetectable		 1gfzA-4wqtX:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 1.04A 1l5qA-4wqtX:
undetectable		 1l5qA-4wqtX:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 0.97A 1l5qB-4wqtX:
2.0		 1l5qB-4wqtX:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 1.02A 1l7xA-4wqtX:
undetectable		 1l7xA-4wqtX:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 1.04A 1l7xB-4wqtX:
undetectable		 1l7xB-4wqtX:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 1.01A 3dd1A-4wqtX:
2.2		 3dd1A-4wqtX:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 1.00A 3dd1B-4wqtX:
undetectable		 3dd1B-4wqtX:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 1.00A 3ddsA-4wqtX:
undetectable		 3ddsA-4wqtX:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 0.99A 3ddsB-4wqtX:
undetectable		 3ddsB-4wqtX:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 0.98A 3ddwA-4wqtX:
undetectable		 3ddwA-4wqtX:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)
(Thermus
thermophilus) 		4 / 6 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 0.98A 3ddwB-4wqtX:
undetectable		 3ddwB-4wqtX:
11.10