SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wsp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4wsp PROTEIN DL-RV1738
(Mycobacterium
tuberculosis) 		4 / 6 ARG A  65
ALA A  45
ILE A  57
PRO A  49
 CL  A 101 ( 3.5A)
CL  A 101 ( 4.0A)
None
None
 1.06A 1oniB-4wspA:
undetectable
1oniC-4wspA:
undetectable		 1oniB-4wspA:
26.09
1oniC-4wspA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4wsp PROTEIN DL-RV1738
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  57
PRO A  49
ARG A  65
ALA A  45
 None
None
CL  A 101 ( 3.5A)
CL  A 101 ( 4.0A)
 1.12A 1oniD-4wspA:
undetectable
1oniE-4wspA:
undetectable		 1oniD-4wspA:
26.09
1oniE-4wspA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4wsp PROTEIN DL-RV1738
(Mycobacterium
tuberculosis) 		4 / 6 ARG A  65
ALA A  45
ILE A  57
PRO A  49
 CL  A 101 ( 3.5A)
CL  A 101 ( 4.0A)
None
None
 1.05A 1oniH-4wspA:
undetectable
1oniI-4wspA:
undetectable		 1oniH-4wspA:
26.09
1oniI-4wspA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4wsp PROTEIN DL-RV1738
(Mycobacterium
tuberculosis) 		4 / 7 ILE A  57
PRO A  49
ARG A  65
ALA A  45
 None
None
CL  A 101 ( 3.5A)
CL  A 101 ( 4.0A)
 1.03A 1oniG-4wspA:
undetectable
1oniI-4wspA:
undetectable		 1oniG-4wspA:
26.09
1oniI-4wspA:
26.09