SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wss'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 ASP A 109
SER A  77
ILE A 301
GLY A 302
 None
 0.72A 1me7A-4wssA:
undetectable		 1me7A-4wssA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 GLU A 492
HIS A 470
GLU A 493
 None
 0.72A 2x45B-4wssA:
undetectable		 2x45B-4wssA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 GLU A 492
HIS A 470
GLU A 493
 None
 0.70A 2x45C-4wssA:
undetectable		 2x45C-4wssA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 GLN A  15
THR A  14
HIS A 439
LEU A 436
 None
 1.22A 2zj0A-4wssA:
undetectable		 2zj0A-4wssA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 TYR A 307
GLU A 425
ASP A  17
 None
 0.80A 3bxoB-4wssA:
undetectable		 3bxoB-4wssA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 GLN A  15
THR A  14
HIS A 439
LEU A 436
 None
 1.12A 3ce6A-4wssA:
undetectable		 3ce6A-4wssA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 GLN A  15
THR A  14
HIS A 439
LEU A 436
 None
 1.14A 3ce6C-4wssA:
undetectable		 3ce6C-4wssA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 GLN A  15
THR A  14
HIS A 439
LEU A 436
 None
 1.11A 3ce6D-4wssA:
undetectable		 3ce6D-4wssA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 THR A  57
GLU A 397
HIS A 396
 None
 0.79A 3g1uB-4wssA:
undetectable		 3g1uB-4wssA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 LYS A 102
LEU A 101
GLU A  58
LEU A  95
 None
 1.15A 4k4yA-4wssA:
undetectable		 4k4yA-4wssA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 LYS A 102
LEU A 101
GLU A  58
LEU A  95
 None
 1.17A 4k4yE-4wssA:
undetectable		 4k4yE-4wssA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 LYS A 102
LEU A 101
GLU A  58
LEU A  95
 None
 1.16A 4k4yI-4wssA:
undetectable		 4k4yI-4wssA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 GLN A  15
THR A  14
HIS A 439
LEU A 436
 None
 1.33A 4lvcA-4wssA:
undetectable		 4lvcA-4wssA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 ILE A  61
GLY A  63
ILE A 249
LEU A 101
 None
 0.78A 4o8fB-4wssA:
undetectable		 4o8fB-4wssA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_2
(-)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 GLN A  15
THR A  14
HIS A 439
LEU A 436
 None
 1.29A 6f3nB-4wssA:
undetectable		 6f3nB-4wssA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 GLN A  15
THR A  14
HIS A 439
LEU A 436
 None
 1.30A 6gbnA-4wssA:
undetectable		 6gbnA-4wssA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 4wss HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 GLN A  15
THR A  14
HIS A 439
LEU A 436
 None
 1.29A 6gbnD-4wssA:
undetectable		 6gbnD-4wssA:
22.71