SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wtb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		4 / 7 GLY A  29
HIS A  47
TYR A  51
PRO A  59
 None
ZN  A 201 (-3.1A)
None
None
 0.44A 1th6A-4wtbA:
21.3		 1th6A-4wtbA:
55.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		9 / 12 LEU A   2
GLY A  22
GLY A  29
GLY A  32
ARG A  33
LYS A  48
TYR A  51
PRO A  59
LYS A  61
 None
None
None
None
None
ZN  A 201 ( 4.2A)
None
None
None
 0.83A 1y4lA-4wtbA:
24.0		 1y4lA-4wtbA:
94.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		10 / 11 LEU A   2
LEU A   5
VAL A  30
GLY A  32
ARG A  33
HIS A  47
LYS A  48
TYR A  51
LYS A  60
LYS A  61
 None
None
None
None
None
ZN  A 201 (-3.1A)
ZN  A 201 ( 4.2A)
None
None
None
 0.95A 1y4lB-4wtbA:
24.1		 1y4lB-4wtbA:
94.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_2
(PHOSPHOLIPASE A2
HOMOLOG 2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		7 / 11 LEU A   5
VAL A  30
ARG A  33
HIS A  47
LYS A  48
TYR A  51
LYS A  52
 None
None
None
ZN  A 201 (-3.1A)
ZN  A 201 ( 4.2A)
None
None
 0.82A 1y4lB-4wtbA:
24.1		 1y4lB-4wtbA:
94.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		4 / 7 GLY A  29
HIS A  47
TYR A  51
PRO A  59
 None
ZN  A 201 (-3.1A)
None
None
 0.47A 2armA-4wtbA:
21.3		 2armA-4wtbA:
55.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		6 / 11 LEU A   5
GLY A   6
LYS A  15
PRO A  17
SER A  20
LYS A 105
 None
 0.74A 3bjwB-4wtbA:
21.4		 3bjwB-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		5 / 7 LYS A   7
GLN A  11
GLY A  14
ARG A  97
LEU A 100
 None
 0.65A 3bjwB-4wtbA:
21.4		 3bjwB-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_3
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
None
None
None
SO4  A 203 (-4.4A)
 0.81A 3bjwG-4wtbA:
20.5		 3bjwG-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_B_SVRB512_3
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
TYR A 107
PHE A 114
 None
None
None
SO4  A 203 (-4.4A)
None
 0.97A 3bjwG-4wtbA:
20.5		 3bjwG-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		6 / 11 LEU A   5
GLY A   6
LYS A  15
PRO A  17
SER A  20
LYS A 105
 None
 0.88A 3bjwE-4wtbA:
21.2		 3bjwE-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_1
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
LYS A 105
TYR A 107
 None
None
None
None
SO4  A 203 (-4.4A)
 0.87A 3bjwA-4wtbA:
20.6		 3bjwA-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_1
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
TYR A 107
PHE A 114
 None
None
None
SO4  A 203 (-4.4A)
None
 0.83A 3bjwA-4wtbA:
20.6		 3bjwA-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		5 / 6 LYS A   7
GLN A  11
GLY A  14
ARG A  97
LEU A 100
 None
 0.92A 3bjwE-4wtbA:
21.2		 3bjwE-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		6 / 12 LEU A   5
GLY A   6
LYS A  15
PRO A  17
SER A  20
LYS A 105
 None
 0.76A 3bjwF-4wtbA:
21.5		 3bjwF-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		4 / 8 LYS A  15
TYR A 103
ASN A 104
LYS A 105
 None
 1.02A 3bjwD-4wtbA:
20.5		 3bjwD-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		4 / 8 LYS A  15
TYR A 103
ASN A 104
PHE A 114
 None
 0.98A 3bjwD-4wtbA:
20.5		 3bjwD-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		5 / 7 LYS A   7
GLN A  11
GLY A  14
ARG A  97
LEU A 100
 None
 0.81A 3bjwF-4wtbA:
21.5		 3bjwF-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		4 / 8 GLY A   6
LYS A   7
PRO A  17
ARG A  63
 None
 0.71A 3bjwA-4wtbA:
20.6		 3bjwA-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		5 / 11 LEU A   5
GLY A   6
LYS A  15
PRO A  17
SER A  20
 None
 0.40A 3bjwH-4wtbA:
21.3		 3bjwH-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_1
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		5 / 9 LYS A  15
TYR A 103
ASN A 104
TYR A 107
PHE A 114
 None
None
None
SO4  A 203 (-4.4A)
None
 0.97A 3bjwC-4wtbA:
20.4		 3bjwC-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		4 / 7 GLN A  11
GLY A  14
ARG A  97
LEU A 100
 None
 0.37A 3bjwH-4wtbA:
21.3		 3bjwH-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		4 / 7 LYS A   7
GLY A  14
ARG A  97
LEU A 100
 None
 0.71A 3bjwH-4wtbA:
21.3		 3bjwH-4wtbA:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		4 / 5 HIS A  47
TYR A  51
PRO A  59
LYS A  60
 ZN  A 201 (-3.1A)
None
None
None
 0.53A 3fo7A-4wtbA:
21.4		 3fo7A-4wtbA:
55.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		6 / 6 PHE A   3
LYS A   7
LEU A  10
ASN A  16
PRO A  17
ARG A  63
 None
 0.59A 4yv5B-4wtbA:
23.9		 4yv5B-4wtbA:
94.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		6 / 6 PHE A   3
LYS A   7
LEU A  10
ASN A  16
PRO A  17
ARG A  63
 None
 0.53A 4yv5A-4wtbA:
23.7		 4yv5A-4wtbA:
94.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		8 / 12 LEU A   2
LEU A   5
GLY A  22
GLY A  29
GLY A  32
ARG A  33
LYS A  48
TYR A  51
 None
None
None
None
None
None
ZN  A 201 ( 4.2A)
None
 0.98A 6ce2B-4wtbA:
22.9		 6ce2B-4wtbA:
85.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1
(Bothrops
jararacussu) 		8 / 12 LEU A   5
GLY A  22
GLY A  29
GLY A  32
ARG A  33
LYS A  48
TYR A  51
PRO A  59
 None
None
None
None
None
ZN  A 201 ( 4.2A)
None
None
 0.74A 6ce2B-4wtbA:
22.9		 6ce2B-4wtbA:
85.12