SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wuu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4wuu IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 PHE E  29
TYR E  27
LEU E   4
VAL E  51
 None
 1.45A 1dz6A-4wuuE:
undetectable		 1dz6A-4wuuE:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4wuu IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 TYR E  95
MET E  93
THR E 115
LEU E 116
 None
 1.43A 2eimJ-4wuuE:
undetectable		 2eimJ-4wuuE:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4wuu IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 TYR E  95
MET E  93
THR E 115
LEU E 116
 None
 1.41A 2eimW-4wuuE:
undetectable		 2eimW-4wuuE:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4wuu IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 TYR E  95
MET E  93
THR E 115
LEU E 116
 None
 1.40A 3ag2J-4wuuE:
undetectable		 3ag2J-4wuuE:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4wuu IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 TYR E  95
MET E  93
THR E 115
LEU E 116
 None
 1.40A 3ag4J-4wuuE:
undetectable		 3ag4J-4wuuE:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4wuu IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 6 LEU E 197
GLY E 198
ALA E 133
PRO E 134
 None
 0.43A 3huoA-4wuuE:
undetectable		 3huoA-4wuuE:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_A_PARA500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4wuu IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		5 / 10 SER E  28
PHE E  32
SER E  77
TYR E  55
GLY E  54
 None
 1.48A 4qb9A-4wuuE:
undetectable		 4qb9A-4wuuE:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4wuu IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 TYR E  95
MET E  93
THR E 115
LEU E 116
 None
 1.41A 5z86J-4wuuE:
undetectable		 5z86J-4wuuE:
14.35