SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wwj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4wwj TENA/THI-4 FAMILY
PROTEIN
(Pseudomonas
protegens) 		5 / 10 ILE A 151
ILE A 148
GLY A 214
PHE A   5
TYR A  17
 None
 1.16A 3elzB-4wwjA:
undetectable		 3elzB-4wwjA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4wwj TENA/THI-4 FAMILY
PROTEIN
(Pseudomonas
protegens) 		5 / 10 ILE A 151
ILE A 148
PHE A   5
TYR A  17
PRO A  18
 None
 0.87A 3elzB-4wwjA:
undetectable		 3elzB-4wwjA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 4wwj TENA/THI-4 FAMILY
PROTEIN
(Pseudomonas
protegens) 		5 / 12 GLY A  61
MET A  54
MET A  44
THR A 162
ILE A 158
 GOL  A 304 ( 3.4A)
None
None
GOL  A 304 ( 3.0A)
GOL  A 304 (-4.7A)
 1.15A 4oktA-4wwjA:
2.9		 4oktA-4wwjA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 4wwj TENA/THI-4 FAMILY
PROTEIN
(Pseudomonas
protegens) 		4 / 8 TYR A 233
LYS A  32
THR A 154
ILE A 209
 None
 1.10A 5jhdE-4wwjA:
undetectable
5jhdG-4wwjA:
undetectable		 5jhdE-4wwjA:
22.57
5jhdG-4wwjA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 4wwj TENA/THI-4 FAMILY
PROTEIN
(Pseudomonas
protegens) 		4 / 5 ILE A 208
LEU A 215
GLY A 214
PHE A   5
 None
 0.94A 5kmdC-4wwjA:
undetectable
5kmdD-4wwjA:
undetectable		 5kmdC-4wwjA:
19.01
5kmdD-4wwjA:
19.01