SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wwu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 4wwu MRNA TRANSPORT
REGULATOR MTR2
(Saccharomyces
cerevisiae) 		5 / 10 LEU C  44
LEU C 149
LEU C  30
ILE C  52
PHE C  45
 None
 1.10A 2w9gA-4wwuC:
undetectable		 2w9gA-4wwuC:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4wwu MRNA TRANSPORT
REGULATOR MTR2
(Saccharomyces
cerevisiae) 		4 / 6 THR C  19
THR C  23
ILE C 153
LEU C 151
 None
 0.78A 3deuB-4wwuC:
undetectable		 3deuB-4wwuC:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wwu MRNA TRANSPORT
REGULATOR MTR2
(Saccharomyces
cerevisiae) 		3 / 3 GLN C  75
THR C  76
LEU C  38
 None
 0.76A 3ondA-4wwuC:
undetectable		 3ondA-4wwuC:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 4wwu MRNA TRANSPORT
REGULATOR MTR2
(Saccharomyces
cerevisiae) 		4 / 8 GLY C 164
ASN C 163
PHE C  22
ILE C 157
 None
 0.90A 4j4vC-4wwuC:
undetectable		 4j4vC-4wwuC:
17.72