SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4wwx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 7 HIS B 942
HIS B 937
HIS B 744
THR B 732
 ZN  B1101 (-3.2A)
ZN  B1101 (-3.2A)
None
None
 0.82A 1am6A-4wwxB:
undetectable		 1am6A-4wwxB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 942
HIS B 937
HIS B 744
THR B 732
 ZN  B1101 (-3.2A)
ZN  B1101 (-3.2A)
None
None
 0.81A 1azmA-4wwxB:
undetectable		 1azmA-4wwxB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 942
HIS B 937
HIS B 744
THR B 732
 ZN  B1101 (-3.2A)
ZN  B1101 (-3.2A)
None
None
 0.83A 1bzmA-4wwxB:
undetectable		 1bzmA-4wwxB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU B 672
LEU B 668
VAL B 715
ALA B 554
SER B 598
 None
 1.11A 1dfoA-4wwxB:
undetectable		 1dfoA-4wwxB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU B 672
LEU B 668
VAL B 715
ALA B 554
SER B 598
 None
 1.11A 1dfoB-4wwxB:
undetectable		 1dfoB-4wwxB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU B 672
LEU B 668
VAL B 715
ALA B 554
SER B 598
 None
 1.11A 1dfoC-4wwxB:
undetectable		 1dfoC-4wwxB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU B 672
LEU B 668
VAL B 715
ALA B 554
SER B 598
 None
 1.11A 1dfoD-4wwxB:
undetectable		 1dfoD-4wwxB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU B 672
LEU B 668
VAL B 715
ALA B 554
SER B 598
 None
 1.10A 1eqbA-4wwxB:
undetectable		 1eqbA-4wwxB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU B 672
LEU B 668
VAL B 715
ALA B 554
SER B 598
 None
 1.10A 1eqbB-4wwxB:
undetectable		 1eqbB-4wwxB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU B 672
LEU B 668
VAL B 715
ALA B 554
SER B 598
 None
 1.10A 1eqbC-4wwxB:
undetectable		 1eqbC-4wwxB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU B 672
LEU B 668
VAL B 715
ALA B 554
SER B 598
 None
 1.10A 1eqbD-4wwxB:
undetectable		 1eqbD-4wwxB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 VAL B 987
VAL B 472
MET B1003
ARG B 969
 None
 1.00A 1iepA-4wwxB:
undetectable		 1iepA-4wwxB:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 7 TYR B 928
VAL B 815
GLU B 803
LEU B 882
 None
 1.04A 1j96B-4wwxB:
undetectable		 1j96B-4wwxB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 11 TYR B 928
VAL B 815
GLU B 803
LEU B 882
LEU B 879
 None
 1.21A 1mrqA-4wwxB:
undetectable		 1mrqA-4wwxB:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 795
ASP B 792
SER B 598
THR B 625
 None
 1.22A 1rg9A-4wwxB:
undetectable		 1rg9A-4wwxB:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 795
ASP B 792
SER B 598
THR B 625
 None
 1.21A 1rg9B-4wwxB:
undetectable		 1rg9B-4wwxB:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 942
HIS B 937
HIS B 744
THR B 732
 ZN  B1101 (-3.2A)
ZN  B1101 (-3.2A)
None
None
 0.77A 2gehA-4wwxB:
undetectable		 2gehA-4wwxB:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 942
HIS B 937
HIS B 744
THR B 732
 ZN  B1101 (-3.2A)
ZN  B1101 (-3.2A)
None
None
 0.76A 2it4A-4wwxB:
undetectable		 2it4A-4wwxB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 7 VAL B 987
VAL B 472
MET B1003
ARG B 969
 None
 1.08A 3mssB-4wwxB:
undetectable		 3mssB-4wwxB:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 5 LEU B 538
ALA B 670
MET B 658
THR B 552
 None
 1.31A 3vasB-4wwxB:
undetectable		 3vasB-4wwxB:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 942
HIS B 937
HIS B 744
THR B 732
 ZN  B1101 (-3.2A)
ZN  B1101 (-3.2A)
None
None
 0.83A 3w6hA-4wwxB:
undetectable		 3w6hA-4wwxB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JI8_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		3 / 3 LYS B 653
LYS B 997
TRP B 992
 None
 1.29A 4ji8L-4wwxB:
0.0		 4ji8L-4wwxB:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 9 TYR B 928
VAL B 815
GLU B 803
LEU B 882
LEU B 879
 None
 1.19A 4l1xB-4wwxB:
undetectable		 4l1xB-4wwxB:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 942
HIS B 937
HIS B 744
THR B 732
 ZN  B1101 (-3.2A)
ZN  B1101 (-3.2A)
None
None
 0.77A 4n16A-4wwxB:
undetectable		 4n16A-4wwxB:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 GLU B 786
THR B 787
THR B 669
HIS B 665
 None
 1.37A 4pfjB-4wwxB:
undetectable		 4pfjB-4wwxB:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 6 GLU B 597
TYR B 707
ILE B 785
THR B 787
 None
 1.42A 4qwpA-4wwxB:
2.8		 4qwpA-4wwxB:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB302_1
(CHITOSANASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 5 GLU B 597
TYR B 707
ILE B 785
THR B 787
 None
 1.43A 4qwpB-4wwxB:
2.6		 4qwpB-4wwxB:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 795
ASP B 792
SER B 598
THR B 625
 None
 1.16A 5t8sB-4wwxB:
undetectable		 5t8sB-4wwxB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 942
HIS B 937
HIS B 744
THR B 732
 ZN  B1101 (-3.2A)
ZN  B1101 (-3.2A)
None
None
 0.79A 5tt3F-4wwxB:
undetectable		 5tt3F-4wwxB:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		4 / 8 HIS B 942
HIS B 937
HIS B 744
THR B 732
 ZN  B1101 (-3.2A)
ZN  B1101 (-3.2A)
None
None
 0.94A 5tt3H-4wwxB:
undetectable		 5tt3H-4wwxB:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 10 MET B 578
ILE B 631
ASP B 585
LEU B 575
PHE B 591
 None
 1.50A 6b4yA-4wwxB:
undetectable		 6b4yA-4wwxB:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 10 LEU B 655
ALA B 562
PRO B 674
SER B 539
VAL B 532
 None
 1.42A 6b89B-4wwxB:
2.7		 6b89B-4wwxB:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 PHE B 557
LEU B 672
VAL B 532
ILE B 535
ASP B 536
 None
 1.20A 6bxmA-4wwxB:
undetectable		 6bxmA-4wwxB:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4wwx V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1
(Mus
musculus) 		5 / 12 LEU B 657
SER B 561
VAL B 532
ILE B 535
ASP B 536
 None
 1.32A 6bxnA-4wwxB:
undetectable		 6bxnA-4wwxB:
20.45